re: Moderna launches coronavirus vaccine Phase 3 trial - 30,000 US Participants

CNBC said the 45 participants in phase 2, 40 were white and 5 blacks.

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In addition to this, the Oxford/AstraZeneca vaccine signed like $250 million dollars worth of deals with Emergent (Baltimore based) to produce vaccines. US govt already gave Emergent more than half a billion dollars to expand capacity to produce vaccines.

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Well, yeah. How else is this administration going to bribe Big Pharma to "lower" insulin and other hot button Rx prices?

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You would think that they would look for participants with the lowest at-risk potential, LIKE COLLEGE STUDENTS, and purposefully expose them to see if the vaccine works.

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I can’t find the article where I read it awhile back but it’s my understanding when surveying for participants they’re looking for people who will be exposed to higher viral loads to participate. Healthcare workers, those working with the public, etc.

[quote]This is the one that Fauci is affiliated with.

Where’s the MSM when you need them? The fricking story writes itself, there’s laws against this sort of thing for the other 99%. It’s like letting Saban head the playoff search committee for Christ’s sake.

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Not if they select people who are already being readily exposed due to their current job or lifestyle. That’s well within ethics standards for these kind of studies.

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There is a difference between using people who may be naturally exposed and intentionally giving it to them.

You can't intentionally give a prostitute gonorrhea to see how a treatment works, just because her lifestyle already readily exposes her to it.

The Oxford vaccine has elicited side effects in 60%+ of patients, but they're mild (headaches mostly and fever in about 15%) and usually go away pretty quickly, so they're looking into possibly going for the 2 dose method similar to the Moderna vaccine or just supplementing it with Tylenol.


It's fascinating to me how quickly these are getting done. If they're successful, these men and women deserve to eat and drink for free for the rest of their lives. Mind blowing shite.

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Even if the group has less than a .04% chance of getting really sick or exhibiting any symptoms whatsoever, AND, they will be under doctor's care and evaluation the entire time?

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You can ethically have a participant that is already regularly exposed to the virus (like a healthcare worker).

You can’t ethically give someone the vaccine trial and then stick them in a room with COVID-19 positive subjects to force exposure.

Let’s hope for as few SAEs as possible.

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I believe this one is a more traditional vaccine, not the mRNA one like Moderna that is a new style.

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it's not RNA based but it is still experimental

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AZD1222, which was developed by researchers at Oxford’s Jenner Institute, works differently, by using a genetically engineered virus, called adenovirus, which was taken from chimps and modified not to replicate and sicken people. It carries a gene for one of the proteins in SARS-Cov-2 and inserts it into a recipient’s cells. The virus causes the patient’s cells to make that protein, which is then recognized by the immune system as foreign. This results in an immune response.

The platform has not been used in an approved vaccine. But it has been used in experimental vaccines against the viruses that cause other outbreaks, including the Ebola virus and the virus that causes Middle East respiratory syndrome (MERS). That work left the Oxford group ready when SARS-CoV-2, a related virus, became a threat.

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