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re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***

Posted on 3/18/20 at 4:06 pm to
Posted by gumpinmizzou
Member since May 2017
3454 posts
Posted on 3/18/20 at 4:06 pm to
I continually hear more positive things about Chloroquine as a treatment.

Seems like reason for optimism, but I am no expert. For the medical folks on here, what do y'all think?
Posted by Fun Bunch
New Orleans
Member since May 2008
131434 posts
Posted on 3/18/20 at 4:08 pm to
Chloroquine and Remdisivir or Avagan need to start being used everywhere. Immediately.
Posted by tiger91
In my own little world
Member since Nov 2005
40251 posts
Posted on 3/18/20 at 4:10 pm to
I'd like to ask who the lover of the downvote button is???
Posted by Volvagia
Fort Worth
Member since Mar 2006
53552 posts
Posted on 3/18/20 at 4:11 pm to
quote:

Isn't this fairly comparable to Influenza numbers?


The overall hospitalization rate for flu this year is at .06%


So no. Not even slightly comparable.

I mean seriously? You think 1 out of 5 people who get the flu between ages 20 and 45 need hospitalization?


Are your blinders on that firmly?
This post was edited on 3/18/20 at 4:20 pm
Posted by gumpinmizzou
Member since May 2017
3454 posts
Posted on 3/18/20 at 4:11 pm to
quote:

Fun Bunch


I tend to agree, but unsure if that's realistic, don't really know about supplies and things like that.

Are you in the medical field?
Posted by VABuckeye
NOVA
Member since Dec 2007
38283 posts
Posted on 3/18/20 at 4:13 pm to
I hear you. It’s just the 100% are cured and he Facebook link in he initial post.
Posted by Volvagia
Fort Worth
Member since Mar 2006
53552 posts
Posted on 3/18/20 at 4:14 pm to
quote:



People are also in a panic right now so how many of those are a result of that panic that otherwise might stay home and self medicate?


Unless my terminology is off, hospitalization refers to being admitted.

Not being pandered to in the ER for a few hours before getting booted.
Posted by Fun Bunch
New Orleans
Member since May 2008
131434 posts
Posted on 3/18/20 at 4:16 pm to
I am not.

My understanding is that chloroquine is one of the most available, cheap, easily produced drug their is.
Posted by Unknown_Poster
Member since Jun 2013
5758 posts
Posted on 3/18/20 at 4:18 pm to
PUMP IT INTO THE WATER!!! ZOMG!
Posted by Paige
Vice President of the OT
Member since Oct 2010
85640 posts
Posted on 3/18/20 at 4:20 pm to
Scruffy hates it
Posted by Scruffy
Kansas City
Member since Jul 2011
77878 posts
Posted on 3/18/20 at 4:21 pm to
quote:

Scruffy hates it
Posted by SlowFlowPro
With populists, expect populism
Member since Jan 2004
481186 posts
Posted on 3/18/20 at 4:22 pm to
people slanging forsythia up in hur
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 3/18/20 at 4:23 pm to
quote:

I posted it for reference. There's a now published paper on Chloroquine from Stanford. Check the links.


Just looked over the paper

Couple of criticisms:
- 6 people out of the treatment group dropped out (3 went to ICU and 1 died). None dropped out of control group.
- the end point of the study was negative nasal swabs. This doesn’t tell us anything about reducing the risk of intubation or death.

Positives:
- The results show it was very effective at reducing the viral load in the nasal swabs.
- Hydroxychloroquine + Azithromycin was even more effective.
- the treatment group was older by an average of 15 years. Meaning if the ages were matched in the groups the effect may be even more dramatic.

Overall:
Positive news. We now need to look at end points of progression to ICU, need for intubation, and death.
If I was diagnosed and developed shortness of breath I would want hydroxychloroquine and azithromycin. Two safe, well studied medications.
Posted by gumpinmizzou
Member since May 2017
3454 posts
Posted on 3/18/20 at 4:29 pm to
Thanks for your thoughts

And thanks to all who post useful info and studies. Much appreciated
Posted by tigercraig
Baton Rouge
Member since Sep 2003
3834 posts
Posted on 3/18/20 at 4:31 pm to
Can you get hydroxychloroquine OTC?
Posted by Volvagia
Fort Worth
Member since Mar 2006
53552 posts
Posted on 3/18/20 at 4:33 pm to
Oh god.

It’s safeish but there would be soooo many morons ODing on it if you could.
Posted by Centinel
Idaho
Member since Sep 2016
46636 posts
Posted on 3/18/20 at 4:34 pm to
quote:

Oh god.

It’s safeish but there would be soooo many morons ODing on it if you could.


Let's cut to the chase here. Can you snort it or do you need to mainline it?

Posted by CivilTiger83
Member since Dec 2017
2525 posts
Posted on 3/18/20 at 4:35 pm to
quote:

Professor Crisanti warned that that for every patient that shows symptoms for COVID-19 there were about 10 who don't.


Great info, but I have another takeaway... This is one more data point that says that COVID-19 is much more pervasive than we think it is.

If the number of cases of COVID-19 is actually 10 times what we think it is in the US, are we going to do more harm than good if this is basically on par with H1N1 for 80-90% of the population?
Posted by Tiguar
Montana
Member since Mar 2012
33131 posts
Posted on 3/18/20 at 4:36 pm to
chloroquine is not available in the United States, or very limited availability, at this time. We all have to use Hydroxychloroquine for the time being
This post was edited on 3/18/20 at 4:37 pm
Posted by Scruffy
Kansas City
Member since Jul 2011
77878 posts
Posted on 3/18/20 at 4:36 pm to
quote:

If the number of cases of COVID-19 is actually 10 times what we think it is in the US, are we going to do more harm than good if this is basically on par with H1N1 for 80-90% of the population?
Absolutely.
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