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Message
Coming Soon - Male birth control shot
Posted on 5/8/26 at 8:28 am
Posted on 5/8/26 at 8:28 am
quote:
They should make birth control for men...
Because it makes more sense to fire blanks than shoot at a bulletproof vest.
https://scitechdaily.com/male-birth-control-breakthrough-scientists-find-way-to-turn-sperm-production-off-and-back-on/
quote:
Cornell University scientists have made significant progress toward what many consider the holy grail of male birth control: a safe, long-acting, fully effective, and nonhormonal contraceptive that can be reversed.
quote:
Today, men have limited contraceptive choices, mainly condoms and vasectomies. While vasectomies offer a long-term solution, many men are hesitant to undergo the procedure, even though it can sometimes be reversed with additional surgery. At the same time, efforts to develop hormonal male contraceptives have faced concerns, partly because similar treatments have shown risks in women.
Cohen and her colleagues focused specifically on meiosis instead of other stages of sperm development to ensure that sperm production could be fully stopped while remaining reversible and without affecting overall reproductive function.
quote:
If this approach is successfully developed for humans, it could lead to a new form of male birth control delivered as an injection every three months or possibly as a patch to maintain effectiveness, Cohen said.
14
Posted on 5/8/26 at 8:29 am to Shexter
This post was edited on 5/8/26 at 8:31 am
Posted on 5/8/26 at 8:30 am to Shexter
quote:
They should make birth control for men... Because it makes more sense to fire blanks than shoot at a bulletproof vest.
I like this tagline!
Posted on 5/8/26 at 8:30 am to Shexter
quote:
Because it makes more sense to fire blanks than shoot at a bulletproof vest.
So you would rather take shots over a period of time vs a 20 minute snip snip?
Posted on 5/8/26 at 8:30 am to Shexter
Not needed baw
Around here we get ourselves a vasectomy and then wonder why we gotta get on trt a couple months later
Around here we get ourselves a vasectomy and then wonder why we gotta get on trt a couple months later
Posted on 5/8/26 at 8:31 am to Duckman13
quote:
So you would rather take shots over a period of time vs a 20 minute snip snip?
“Just cut your balls off bro”
Posted on 5/8/26 at 8:31 am to Shexter
But that would eliminate the need to pull out and go on her face.
Posted on 5/8/26 at 8:33 am to Duckman13
quote:
So you would rather take shots over a period of time vs a 20 minute snip snip?
Do you seriously not realize the temporary and long term difference of the two?
Posted on 5/8/26 at 8:33 am to Duckman13
quote:
So you would rather take shots over a period of time vs a 20 minute snip snip?
The reversible part is the selling point.
How many women would rather be on birth control vs getting a partial hysterectomy?
Posted on 5/8/26 at 8:39 am to Shexter
quote:
The reversible part is the selling point.
Vasectomies are pretty easily reversible, also apparently there are other fairly easy and relatively cheap ways to have a kid without having it reversed regardless. My wife is trying to talk me into one of those
Posted on 5/8/26 at 8:41 am to Shexter
Lupron is already a birth control method even though it’s indicated for prostate cancer
Posted on 5/8/26 at 8:43 am to Shexter
quote:Scruffy will believe this when pigs fly.
production could be fully stopped while remaining reversible and without affecting overall reproductive function.
No go for Scruffy.
Posted on 5/8/26 at 8:44 am to Shexter
Vasectomy is pretty awesome. Wife isn't on any birth control and I haven't pulled out in 6 years.
Posted on 5/8/26 at 8:44 am to Shexter
Will be interesting to see where this goes come time for human trials. Since it's non-hormonal it has to be an RARa blocker that blocks vitamin A receptors to trigger meiosis. Three things to watch will be how many participants have a 'rebound' where the blocker become ineffective over time. What is the timeline for meiosis to restart after the blocker is stopped. How many participants see blocking beyond the targeted receptors. Concern with the latter is if additional receptors other than those targeted block vitamin A there will be vision loss (hopefully reversible once the RARa blocker is stopped). For the masses #2 will be the only factor, just to see if it's a 1 month or 6 month timeline between starting and stopping. Other two are going to be the outliers (hopefully).
Posted on 5/8/26 at 8:46 am to Shexter
quote:
production could be fully stopped while remaining reversible and without affecting overall reproductive function.
Totally believable. What about hormonal balance in males including testosterone production?
Posted on 5/8/26 at 8:48 am to Shexter
It's not nice to fool with mother nature.
Posted on 5/8/26 at 8:50 am to Shexter
Dudes about to be busting
Posted on 5/8/26 at 8:52 am to Shexter
I trust that it will lower men's testosterone levels until they are all Beta she-males.
Posted on 5/8/26 at 9:03 am to theCrusher
quote:That is why the target is RAR-alpha receptors. Beta and Gamma receptors are the ones that would effect testosterone production and subsequently prostate and libido health. The compound they are using based on the current studies is highly selective and as of now shows very little to no crossover, but most of the found crossover is to other alpha receptors like in the pupil which on healthy individuals is more than compensated for by the beta receptors that deal with eye health.
What about hormonal balance in males including testosterone production?
Posted on 5/8/26 at 9:04 am to AwesomeSauce
quote:
To achieve this, the team used JQ1, a small molecule inhibitor originally developed as a research tool for studying cancer and inflammatory diseases. Although JQ1 is not suitable as a treatment due to neurological side effects, it is known to interfere with a specific stage of meiosis called prophase 1. This allowed the researchers to demonstrate for the first time that sperm production can be safely and reversibly stopped by targeting meiosis and sperm production at this stage.
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