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re: Antibody study in Netherlands shows that 3% had coronavirus. What it means for us.

Posted on 4/16/20 at 6:08 pm to
Posted by BluegrassBelle
RIP Hefty Lefty - 1981-2019
Member since Nov 2010
109014 posts
Posted on 4/16/20 at 6:08 pm to
quote:

This once again raises the question of what the hell is going on with testing in the US?


Kentucky Governor Beshear announced in his press conference yesterday that they were partnering with the University of Louisville for antibody testing in the region. Specifically among healthcare workers.

quote:

LOUISVILLE, Ky. —
In Gov. Andy Beshear's Wednesday press conference, he announced the first stage of a unique testing regime that is designed to save lives and get people back to work.

The Co-Immunity Project is a collaboration among the State of Kentucky, Louisville Metro Government, the Christina Lee Brown Environmental Institute and several major health care companies.

The project will focus on comprehensive testing, centered on antibodies and developing donor plasma resources.

“It will test for antibodies for those who have been infected in the past and may have developed immunity,” the Beshear said.


quote:

“This is a unique opportunity for us to leverage all of the research capabilities of the University of Louisville,” said University of Louisville President Neeli Bendapudi. “We are very eager to try to work with the entire population, first of all to protect our health care workers and then everyone in the community and hopefully from Louisville we are able to take this and extend it to enhancing the health of the entire commonwealth.”


I have no doubt we're not the only state with a major University doing this.

LINK
Posted by SloaneRanger
Upper Hurstville
Member since Jan 2014
14343 posts
Posted on 4/16/20 at 6:30 pm to
And what does this do exactly? So lets say you can do antibody tests on every single person in the state (highly unlikely). By doing that you discover that 7% of the state's population has the antibodies. Then what? What do you do with that information? Are you going to tell the 93% sorry you can't come back to work?

I am having a hard time understanding the infatuation with testing as a be all end all solution. Maybe someone can explain it to me.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 4/16/20 at 6:31 pm to
quote:

And for this we took the best economy we’ve ever had and destroyed it to the point we’re reaching depression levels.


You need to calm down. You are just as bad as all the doomsayers you despise, you are just spewing doom about a different topic.

You act like you know for sure the economy would have been just fine if we would have just “continued like nothing was happening”... an idea that is literally impossible and you know it.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 4/16/20 at 6:34 pm to
quote:

I am having a hard time understanding the infatuation with testing as a be all end all solution.


It’s not a solution. It just allows us to more accurately predict the future. All of our policy is being made based on models. Models which haven’t proven to be very accurate yet. More data means more accurate models which in turn means better policy.

Everything that we did was based on presumed percentage of critical patients and deaths.
Posted by fightin tigers
Downtown Prairieville
Member since Mar 2008
79881 posts
Posted on 4/16/20 at 6:51 pm to
A lot of NOLA showed symptoms and didn't get tested
Posted by GOP_Tiger
Baton Rouge
Member since Jan 2005
21187 posts
Posted on 4/16/20 at 7:09 pm to
If 10% of the population has been infected, it's still significant in our efforts to control the virus.

People talk about herd immunity, and of course we aren't going to get there anytime soon (something like 50-70% of the population) -- but we don't need true herd immunity to lower the R value of the virus to the point that we can control it with very minor measures.

If 10% of the population truly has antibodies to COVID-19, it will mean that we can likely open up things faster. Eventually, it would start to make things like fans at sporting events seem like a little less of an insane idea.
Posted by DrewSimp82
Shreveport
Member since Apr 2007
1675 posts
Posted on 4/16/20 at 7:14 pm to
It’s not apples to apples my friend. You’re comparing the death rate of probably some of the healthiest people on the planet to probably the most obese, hypertension and diabetes ridden region of the world.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 4/16/20 at 7:49 pm to
quote:

If 10% of the population truly has antibodies to COVID-19, it will mean that we can likely open up things faster. Eventually, it would start to make things like fans at sporting events seem like a little less of an insane idea.


Exactly. I thought this would be obvious from the OP. I was trying to keep it brief, but your analysis is exactly the point I was hoping to convey.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 4/16/20 at 7:50 pm to
quote:

It’s not apples to apples my friend. You’re comparing the death rate of probably some of the healthiest people on the planet to probably the most obese, hypertension and diabetes ridden region of the world.


You are making a lot of assumptions as well.

Healthcare
Genetics
Smoking
Age (average age in Netherlands if 42 vs 32 in New Orleans)

We don’t know for sure. It’s just a rough estimate.
Posted by fightin tigers
Downtown Prairieville
Member since Mar 2008
79881 posts
Posted on 4/16/20 at 8:06 pm to
Netherlands hypertension rates are almost the exact same as Louisiana.


If we want to look at hypertension....the leading comorbidity.
Posted by HeadSlash
TEAM LIVE BADASS - St. GEORGE
Member since Aug 2006
56639 posts
Posted on 4/16/20 at 8:17 pm to
quote:


Or people in NOLA are waaaaayyy more unhealthy than in Netherlands


THIS
Posted by baldona
Florida
Member since Feb 2016
24485 posts
Posted on 4/16/20 at 8:18 pm to
quote:

The only FDA approved test with a legitimate lab test study that I’ve seen showed a 98.4% specificity for the lgg antibody but with low sensitivity with a 96% agreement for negative results with the lgm antibody and 93% agreement for positive results.

So even using that 98.4%, that would mean a 1% infection rate would result in 1.58% of the sample testing falsely positive.


Can you explain this like I’m 5?
Posted by fightin tigers
Downtown Prairieville
Member since Mar 2008
79881 posts
Posted on 4/16/20 at 8:20 pm to
Italy is way healthier than NOLA as well.

We see how that worked out for them.
Posted by NorCali
Member since Feb 2015
1822 posts
Posted on 4/16/20 at 9:16 pm to
This is not a hopeful sign. Need 50% either by exposure or vaccination for herd immunity. Would like to see closer to 25% so that you are over half way there. Means they will need to stay shut down to international travel until vaccination, which is tough since they are the new London for a few things like EMA post Brexit.
Posted by RandySavage
9 Time Natty Winner
Member since May 2012
35824 posts
Posted on 4/16/20 at 9:25 pm to
If the tandem float don't get ya than the Rona will.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 4/16/20 at 9:57 pm to
quote:

This is not a hopeful sign.


Why? An infection fatality rate of 0.6% doesn’t seem better to you? It not only cuts the number of deaths by a lot it also cuts the projected resources needed by a lot.

Let’s say remdesivir and other therapies can cut that mortality rate in half. Then we are only looking at 0.3% mortality rate.
Posted by MoarKilometers
Member since Apr 2015
21434 posts
Posted on 4/16/20 at 10:00 pm to
Seems like really bad math to extrapolate death data from a country whose 2nd and 3rd highest death totals were today and yesterday. Not that all Corona math hasn't been woefully turrible.
Posted by fightin tigers
Downtown Prairieville
Member since Mar 2008
79881 posts
Posted on 4/16/20 at 10:00 pm to
quote:

remdesivir


Has been a ton of hype on this the last 48 hours or so
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 4/16/20 at 10:01 pm to
I’m open to you providing a more accurate infection fatality rate
Posted by MoarKilometers
Member since Apr 2015
21434 posts
Posted on 4/16/20 at 10:07 pm to
quote:

I’m open to you providing a more accurate infection fatality rate

I'm open to them listing how many people were in this pool of tested folks and disclosing how they were selected for testing. Garbage in, garbage out prevents anyone from legitimately throwing out an accurate number from this.
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