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Animal protein and endothelial damage

Posted on 3/18/24 at 2:11 pm
Posted by Earnest_P
Member since Aug 2021
3485 posts
Posted on 3/18/24 at 2:11 pm
A family member of mine recently entirely gave up meat and animal products after getting tested and found to have 50% blockage in artery (IIRC).

When I questioned her about the wisdom of this, she told me it’s not the saturated fat alone she is avoiding, it’s that research has shown that the amino acids in animal proteins damage endothelial cells.

When she told me this I was a bit taken aback because I hadn’t heard that specifically before. Google led me to this A Plant-Based Diet, Atherogenesis, and Coronary Artery Disease Prevention
quote:

A plant-based diet is increasingly becoming recognized as a healthier alternative to a diet laden with meat. Atherosclerosis associated with high dietary intake of meat, fat, and carbohydrates remains the leading cause of mortality in the US. This condition results from progressive damage to the endothelial cells lining the vascular system


What say y’all? I’m skeptical of any anti-meat information but I want to keep an open mind.

Seems odd that we would evolve to need amino acids that are deadly.
This post was edited on 3/18/24 at 2:19 pm
Posted by BilbeauTBaggins
probably stuck in traffic
Member since May 2021
4307 posts
Posted on 3/18/24 at 2:17 pm to
If I could cut red meat out completely I would, but life is too short to taste so boring. It's probably also too short because I eat so much of it.
Posted by Mo Jeaux
Member since Aug 2008
58556 posts
Posted on 3/18/24 at 2:57 pm to
quote:

If I could cut red meat out completely I would


Why?
Posted by lsu777
Lake Charles
Member since Jan 2004
30966 posts
Posted on 3/18/24 at 2:57 pm to
its bullshite

but to each their own but tell her to look into studies on pomegranate juice, 100% not from concentrate and its ability to reverse the plaque build up.
Posted by Mo Jeaux
Member since Aug 2008
58556 posts
Posted on 3/18/24 at 2:57 pm to
quote:

I’m skeptical of any anti-meat information
Posted by Earnest_P
Member since Aug 2021
3485 posts
Posted on 3/18/24 at 3:06 pm to
quote:

but to each their own but tell her to look into studies on pomegranate juice


I did tell her and also suggested Nattokinase. It’s frustrating to see them
abandoning meat while they simultaneously lose muscle mass. They’ll abandon their diet of 70 years for peas and lentils but won’t lift a weight heavier than the remote.

The abstract on that paper has a lot of “may do” this or that. Also, what seems to me to be prevalent in the mainstream narrative on this stuff is a lot of correlation equals causation which is passed off as proof.

quote:

Atherosclerosis associated with high dietary intake of meat, fat, and carbohydrates remains the leading cause of mortality in the US. This condition results from progressive damage to the endothelial cells lining the vascular system, including the heart, leading to endothelial dysfunction. In addition to genetic factors associated with endothelial dysfunction, many dietary and other lifestyle factors, such as tobacco use, high meat and fat intake, and oxidative stress, are implicated in atherogenesis. Polyphenols derived from dietary plant intake have protective effects on vascular endothelial cells, possibly as antioxidants that prevent the oxidation of low-density lipoprotein. Recently, metabolites of L-carnitine, such as trimethylamine-N-oxide, that result from ingestion of red meat have been identified as a potential predictive marker of coronary artery disease (CAD). Metabolism of L-carnitine by the intestinal microbiome is associated with atherosclerosis in omnivores but not in vegetarians, supporting CAD benefits of a plant-based diet. Trimethylamine-N-oxide may cause atherosclerosis via macrophage activation. We suggest that a shift toward a plant-based diet may confer protective effects against atherosclerotic CAD by increasing endothelial protective factors in the circulation while reducing factors that are injurious to endothelial cells.
Posted by OysterPoBoy
City of St. George
Member since Jul 2013
35009 posts
Posted on 3/18/24 at 3:13 pm to
quote:

Atherosclerosis associated with high dietary intake of meat, fat, and carbohydrates remains the leading cause of mortality in the US


What else is there?
Posted by Earnest_P
Member since Aug 2021
3485 posts
Posted on 3/18/24 at 3:14 pm to
quote:

What else is there?


Maybe the goal is to have a patient who dies of starvation with perfectly clear arteries.
Posted by Shepherd88
Member since Dec 2013
4579 posts
Posted on 3/18/24 at 3:31 pm to
That article is nearly 10 years old. There’s been more research to come out since then to disprove the red meat propaganda.
Posted by Earnest_P
Member since Aug 2021
3485 posts
Posted on 3/18/24 at 3:36 pm to
quote:

That article is nearly 10 years old. There’s been more research to come out since then to disprove the red meat propaganda.


I think it’s what her doctor or whoever advising her is basing the recommendation on. I was looking for research that directly debunked it, and couldn’t find that. The point of the thread is to find it.
This post was edited on 3/18/24 at 3:37 pm
Posted by Shepherd88
Member since Dec 2013
4579 posts
Posted on 3/18/24 at 4:21 pm to
Check out this source.

Health effects associated with consumption of unprocessed red meat: a Burden of Proof study

Summarized article.
Study slams lazy research
This post was edited on 3/18/24 at 4:23 pm
Posted by Earnest_P
Member since Aug 2021
3485 posts
Posted on 3/18/24 at 4:31 pm to
Thanks!
Posted by lsu777
Lake Charles
Member since Jan 2004
30966 posts
Posted on 3/18/24 at 5:33 pm to
Yep natt is another good one. As is citrus bergmont to help with hdl too
Posted by scottydoesntknow
Member since Nov 2023
1976 posts
Posted on 3/18/24 at 8:21 pm to
sounds like gobbledygook to me.
Posted by Big Scrub TX
Member since Dec 2013
33377 posts
Posted on 3/18/24 at 10:21 pm to
quote:

Animal protein and endothelial damage
A family member of mine recently entirely gave up meat and animal products after getting tested and found to have 50% blockage in artery (IIRC).

When I questioned her about the wisdom of this, she told me it’s not the saturated fat alone she is avoiding, it’s that research has shown that the amino acids in animal proteins damage endothelial cells.

When she told me this I was a bit taken aback because I hadn’t heard that specifically before. Google led me to this A Plant-Based Diet, Atherogenesis, and Coronary Artery Disease Prevention
It's just absurd on its face that animal protein would JUST NOW start being bad for people.
Posted by TheFitfulFire
Houma
Member since Jan 2017
145 posts
Posted on 3/20/24 at 10:46 am to
It makes you wonder how much of the "issues"associated with eating meat have to do with meat by itself or rather what yhe animals are eating. I don't know that reasearch has been done into the health factor of say, grass fed and finished beef vs grainfed, or pastured pork and chicken vs grainfed.

I truly believe that factory/industrial farming has done the most harm to our dietary practice.
Posted by Shepherd88
Member since Dec 2013
4579 posts
Posted on 3/20/24 at 12:24 pm to
Grass fed beef is nutrionally better but since cattle have 2 stomachs and can ferment grains it doesn’t make the difference as large as it would in poultry.

The biggest aspect of these older studies casting blame on red meat is they’re sampling individuals who are eating processed red meat (fast food) and basing their assumption simply bc they eat red meat and not where it’s sourced. Also they’re also not considering the other shite that comes with fast food (soda, fries cooked in vegetable oils).
Posted by Ace Midnight
Between sanity and madness
Member since Dec 2006
89486 posts
Posted on 3/20/24 at 1:04 pm to
quote:

but to each their own but tell her to look into studies on pomegranate juice, 100% not from concentrate and its ability to reverse the plaque build up.




777 - 2 questions:

1. What amount of consumption is right?

2. What is the most cost effective source?
Posted by NewOrleansBlend
Member since Mar 2008
1004 posts
Posted on 3/20/24 at 1:20 pm to
There is no good evidence that pomegranate juice reduces atherosclerosis in humans. There is poor quality evidence from one scientist (usually a bad sign, increases the risk of bias, both intentional and unintentional) in Israel, a small study that showed a benefit in humans and some studies showing benefit in mutated rats, however the best study on the subject, a much larger randomized multicenter study performed in 2009, showed no benefit. And the same Israeli guy was the senior author on that paper.

I don’t know why Lsu777 continues to act like this is proven when the best evidence says it doesn’t work.

Study link
This post was edited on 3/20/24 at 1:35 pm
Posted by TheFitfulFire
Houma
Member since Jan 2017
145 posts
Posted on 3/20/24 at 6:40 pm to
Many of those studies were also funded by the sugar industry. Sugar and beef have been biting at each other for years when really, excess is the largest problem. That and non-holistic farming practices.
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