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re: Video: Fouci on Fox and friends gets really triggered about hydroxychloroquine

Posted on 4/4/20 at 12:23 am to
Posted by bfniii
Member since Nov 2005
17840 posts
Posted on 4/4/20 at 12:23 am to
quote:

Most critical care anecdotes I've heard (and these are guys I personally know, for the most part) aren't impressed with their results. Most of the NOLA guys I'm still in touch with don't see a big difference earlier on in the ones who got it vs different from what they've told me so far
this is the exact opposite of what i've been hearing
Posted by bfniii
Member since Nov 2005
17840 posts
Posted on 4/4/20 at 12:24 am to
quote:

Really, remove the guy that has been director of the National Institute of Allergy and Infectious Diseases since 1984, in the middle of a world wide pandemic?
first, people change. second, this is precisely the time when you see people's agendas surface. dem gov's are a perfect example. money grab.
Posted by BeepNode
Lafayette
Member since Feb 2014
10005 posts
Posted on 4/4/20 at 12:44 am to
I have been all aboard the "Let's roll out HQ to everyone and see what happens" train but I gotta say I'm a bit disappointed with some of the results. Spain is giving it to most patients and they're still dropping like flies.

Hopefully those were the people that didn't get it or were too far gone already, but I'm starting to lose hope that this thing is going to just go away.
Posted by Evolved Simian
Bushwood Country Club
Member since Sep 2010
20774 posts
Posted on 4/4/20 at 12:50 am to
quote:

Look at what companies he is a board member of.



Well, which ones?
Posted by RD Dawg
Atlanta
Member since Sep 2012
27323 posts
Posted on 4/4/20 at 12:58 am to
quote:

Really, remove the guy that has been director of the National Institute of Allergy and Infectious Diseases since 1984,


We spend BILLIONS each year on the NIH to specifically gather the intelligence, science,data and predictive models for situations exactly like the one we're in now and they've failed miserably.

And the fact that he's been there for 35 years makes him look even worse
This post was edited on 4/4/20 at 1:00 am
Posted by NC_Tigah
Carolinas
Member since Sep 2003
124706 posts
Posted on 4/4/20 at 5:18 am to
quote:

He's super intentional with his words
He normally has been.
But either he's tired, overexposed, or age is starting to creep in.

Fauci issued oddly unclear opinions in the press recently. He understands the TDS MSM modus operandi. His messaging should be geared to counter that. In the past, it has been. Currently it isn't.

As you say, when parsed, material he's putting out is largely correct.
But it is laid out in a manner open to misinterpretation by a MSM bent on misinterpreting.

Hence the Press represents Fauci saying:
(1) Hydroxychloroquine is ineffective.
(2) Masks will protect the wearer from contracting Covid-19
(3) Covid-19 definitively arose from Wuhan wet markets (rather than lab contamination).

As to 1 & 2, that is not what he has said, but it is what he is allowing as misinterpretation.
e.g., Does Hydroxychloroquine work? Answer: We don't know.
But . . .
when media is breathlessly angling for a "Trump is wrong." "Hydroxychloroquine is voodoo." message, Fauci tacitly gives it to them by saying "we don't know if it works." His answer SHOULD be "We don't know that it doesn't work."

Same with masks. Their primary purpose is not to protect you, but rather to protect others from you.

But the real odd-ball is Fauci's matter-of-fact assertion of Covid-19's wet market origin. Fauci has far more information indicating hydroxychloroquine may work than he does for CV19's wet market origin. His wet market assertions are based on no facts at all. I find that very odd.

======

BTW, my suspicion has always been that if Hydroxychloroquine works, its effect is mitigation rather than cure.
Symptoms reduced rather than eliminated.

We are hearing about HC successes in France and Spain.
Folks like Laura Ingraham tout those claims.
Yet the death rate in France and Spain is nearly 10%.
So something is amiss.

But for now, Trump wants to give folks hope.
There is some justification for what he is saying.
Fauci has made clear the science is not in.
Now he should make clear the POTUS was not wrong to give hope.
Posted by FLTech
the A
Member since Sep 2017
13393 posts
Posted on 4/4/20 at 5:26 am to
This MF is a Clinton plant
Posted by IslandBuckeye
Boca Chica, Panama
Member since Apr 2018
10067 posts
Posted on 4/4/20 at 5:45 am to
quote:

Actual decent controlled studies are underway. That is what Fauci is waiting on.



Understand and agree. I just argue for compassionate use in a rational manner at the level of patient care. We just got our first patient in ICU and we are using it. I think we could have started when we had 10 positive patients on island.

quote:

That is what Fauci is waiting on.



We quit nebulizations based on an unproven theory. This was based on risk. What are the risks of HCQ when prescribed based on H&P and positive results?

Posted by NC_Tigah
Carolinas
Member since Sep 2003
124706 posts
Posted on 4/4/20 at 7:58 am to
quote:

What are the risks of HCQ when prescribed based on H&P and positive results?
Minimal. The caveat of course, is there are risks with nearly anything we do in medicine. Changes in cardiac conduction are rare but significant if they occur. HC can cause drops in blood sugar, etc.

More than anything else, theoretical concerns are impacting. Concerns that high demand will shut out supply for other known beneficial uses. Concerns that unfounded belief in benefit will somehow drive complacency for seeking better therapeutic options.

In my mind if there is a chance HC helps at all, and the actual risks are minimal, you use the stuff until it is either proven worthless, or something better comes along.
Posted by KiwiHead
Auckland, NZ
Member since Jul 2014
28084 posts
Posted on 4/4/20 at 8:01 am to
Anecdotal evidence is not illegitimate evidence. Fauci wants an ideal study.....he is not gonnas get one.
Posted by Boatshoes
Member since Dec 2017
6775 posts
Posted on 4/4/20 at 8:02 am to
quote:

What the frick is up with this dude? There are very promising studies and survivor accounts that attribute the drug to saving their life.


Academic physicians are all about double blind RCTs. They are basically public health officials that think in terms of populations. Many of them think that medicine doesn’t exist outside of RCTs.

Front line clinical physicians are much more likely to assess the risks and benefits of something and give it a try based on case reports and their knowledge of human physiology. They think in terms of what can I do to help the patient I am taking care of today.

Not that double blind RCTs don’t have their place, but if we waited for them to verify everything nothing would get done.
This post was edited on 4/4/20 at 8:04 am
Posted by CleverUserName
Member since Oct 2016
12928 posts
Posted on 4/4/20 at 8:15 am to
quote:

It just has not been proven as such. That is what Fauci is grousing about. Actual decent controlled studies are underway. That is what Fauci is waiting on.


And that’s a problem with the medical community in a crisis. Yea... if this was about the common cold we need to wait for a study.

But I bet you walk into a patient’s room who is about to go on a vent and ask if they want to try it, but but it’s not been studied, then they would say “IDGAF about a study, let’s get started”
Posted by NC_Tigah
Carolinas
Member since Sep 2003
124706 posts
Posted on 4/4/20 at 8:17 am to
quote:

.....he is not gonnas get one.
Yes he will. But until we do, we should use what we have. What we have insinuates therapeutic value at a time when there is no alternative.
Posted by Powerman
Member since Jan 2004
162295 posts
Posted on 4/4/20 at 8:20 am to
quote:

Yes he will. But until we do, we should use what we have. What we have insinuates therapeutic value at a time when there is no alternative.



You're a doctor

And as I can tell a reasonable person

You have to assess risk. From what I understand hydroxychloroquine has shown positive results with critical patients. Which is obviously good.

But given the side effects would it not be irresponsible to prescribe to lower risk patients?
Posted by cwill
Member since Jan 2005
54754 posts
Posted on 4/4/20 at 8:21 am to
quote:

80% of patients in India are being prescribed the drug. Can all of these docs be wrong?




They could, but that doesn’t mean you don’t try it...don’t give effusive false hope, though.
Posted by SlackMaster
Baton Rouge
Member since Jan 2009
2663 posts
Posted on 4/4/20 at 8:25 am to
quote:

hydroxychloroquine has shown positive results with critical patients


I've read the opposite. It must be given early enough to prevent ARDS and there head off the patient becoming critical. Once critical and on a vent, the hydroxychloroquine doesn't help much because the lung damage is mostly done.
Posted by kcon70
Houston, TX
Member since Sep 2016
2695 posts
Posted on 4/4/20 at 8:47 am to
Fauci’s kickbacks from pharmaceutical companies probably equal 10 years of most salaries here.
Posted by Jake88
Member since Apr 2005
68752 posts
Posted on 4/4/20 at 8:57 am to
I understand what Fauci is saying regarding Plaquenil, the problem is he's discussing it as if these are normal times. There aren't solid studies demonstrating its efficacy, yet. But, these aren't normal times and it's time for him to switch to "front lines mode." Hence your statement...
quote:

His answer SHOULD be "We don't know that it doesn't work."
is spot on exactly what should be said.
Posted by Hopeful Doc
Member since Sep 2010
15057 posts
Posted on 4/4/20 at 8:59 am to
quote:

I just argue for compassionate use in a rational manner at the level of patient care.



This still confuses me. Outside of the 2d period where the Michigan governor put an EO banning the use of the drug off-label (side note- I would like to see how that stands up in court), there's never really been a restriction on this. The only thing really affected by the physician who practices based on political endorsement and the news rather than societal recommendation. I just don't know who these people are. I'm sure some exist. I don't think it's a ton of them.

quote:

We quit nebulizations based on an unproven theory.


There is a generally safer direct alternative that has been, in many cases, proven superior with some data starting at 2m of age. The point I'm trying to make isn't, "they should use inhalers all the time anyway" but rather, "nebulizers aren't as vastly superior to inhalers as most (of my patients) seem to think"

quote:

What are the risks of HCQ when prescribed based on H&P and positive results?


The biggest risk is dysrhythmia. It's not a common thing, but it's a real risk. The drug does have a fair number of side effects for chronic use. But short term, not much. Especially in a patient that's being monitored.

The problem is that, as someone who does this day to day and read most of the primary source data out there as of this last weekend, I don't find those results overly impressive. Most of the guys I practice with who broke down the study and read all the data, exclusions, etc aren't either. The anecdotes from the folks I've spoken to aren't the phenomenal "brink of death to better" stories that I see online.

I hope that us cynical bastards are wrong.
Posted by Jake88
Member since Apr 2005
68752 posts
Posted on 4/4/20 at 9:04 am to
quote:

The problem is that, as someone who does this day to day and read most of the primary source data out there as of this last weekend, I don't find those results overly impressive.
Is there anyone looking into the appropriate timing for use of HCQ? Does it prevent significant decline if it's given when O2 sats are above 94%?
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