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re: Sorrento Therapeutics announces breakthrough in anti-body treatments. AKA...a cure
Posted on 5/15/20 at 10:43 am to Jwho77
Posted on 5/15/20 at 10:43 am to Jwho77
I understand but why would this be significantly more effective the the convalescent plasma? That plasma has the most specific antibodies you can find.
Have they tested this new antibody yet?
Have they tested this new antibody yet?
This post was edited on 5/15/20 at 10:44 am
3
Posted on 5/15/20 at 10:57 am to Fun Bunch
DNC better send in Crowdstike to fix this problem
Posted on 5/15/20 at 10:59 am to WaWaWeeWa
The plasma does not necessarily provide the most effective antibodies in high enough numbers that inhibit the coronavirus. Creating a specific cocktail of antibodies in high enough doses can. If it works, you have injectable immunity.
Posted on 5/15/20 at 11:00 am to WaWaWeeWa
quote:
Have they tested this new antibody yet?
quote:
Then, working with collaboration partners at the University of Texas Medical Branch, which has access to the live virus, they were able to screen the dozen antibodies for the most promising ones.
“We’re actually so impressed with the data,” Ji said. “One of the antibodies is so powerful that at a very low concentration it is able to 100% completely prevent infection or inhibit the infection. In our studies, not even one virus escaped from the antibody.”
That was STI-1499. Currently, Sorrento believes STI-1499 will be the first antibody in the three-antibody cocktail, COVI-SHIELD, which it is developing with Mount Sinai. Additionally, because of its high potency, it plans to develop the antibody as a stand-alone therapy, COVI-GUARD.
LINK
Posted on 5/15/20 at 11:07 am to Jwho77
It's going to take quite a while to get it to market because they have to have safety data as well as efficacy
Posted on 5/15/20 at 11:09 am to Diseasefreeforall
Yes
LINK
quote:
Sorrento’s COVID-SHIELD is meant to address this through a potent mix of different antibodies that provide protection against different strains of the virus, but the company says it will also be pursuing development of the STI-1499 antibody on its own as a dedicated, standalone therapy. The company is already in discussion with regulators about how to expedite development of that potential treatment, and is ramping its production capacity as well with the goal of producing as many as one million doses at the same time it pursues FDA approval for its use.
LINK
Posted on 5/15/20 at 11:16 am to Fun Bunch
jumped on that shite. already up 57+%
Posted on 5/15/20 at 11:18 am to Fun Bunch
quote:
Dr. Henry Ji,
Nope.
Posted on 5/15/20 at 11:29 am to Fun Bunch
quote:
"We want to emphasize there is a cure. There is a solution that works 100 percent,"
100 percent, ay? I'd like to see his evidence, because that is quite the claim.
Posted on 5/15/20 at 11:37 am to Fun Bunch
Just looked them up:
10 to the 16th is a pretty damn big number.
quote:
the G-MAB library contains more than 10 quadrillion (10exp 16) distinct antibody sequences. This makes it one of the largest fully human antibody libraries in the biopharmaceutical industry.
10 to the 16th is a pretty damn big number.
Posted on 5/15/20 at 11:39 am to onmymedicalgrind
quote:
100 percent, ay? I'd like to see his evidence, because that is quite the claim.
We all would.
Unfortunately, I don't think we'll see that in the very near term.
Posted on 5/15/20 at 11:40 am to Fun Bunch
Talked with MD’s yesterday, they have been using antibodies with great results
Posted on 5/15/20 at 11:40 am to Fun Bunch
The virus will have died out by the time.... months it is ready.
Posted on 5/15/20 at 11:47 am to WaWaWeeWa
quote:
Have they tested this new antibody yet?
A key question. Another I have stems from quote below.
quote:
"As soon as it is infused, that patient is now immune to the disease," Dr. Brunswick said to Fox News. "For the length of time, the antibody is in that system. So, if we were approved [by the FDA] today, everyone who gets that antibody can go back to work and have no fear of catching COVID-19."
How long does it stay in body? Is it one stop shot? will it convey immunity for any length of time? I am guessing days to maybe weeks. Here is a reference for any other nerds that may be out there.
Tutorial on mAbs Pharmacokinetics
Posted on 5/15/20 at 11:52 am to westide
This is great news two birds with one stone.
Bird one: cure
Bird two: Redpill some people after they see the dims/DS fight this every step of the way.
Bird one: cure
Bird two: Redpill some people after they see the dims/DS fight this every step of the way.
Posted on 5/15/20 at 11:57 am to Fun Bunch
This thread made me thousands of dollars today
Posted on 5/15/20 at 12:03 pm to IslandBuckeye
Tap the breaks. In-vitro results only. They don't even have an approved IND yet (approval to start testing in people.)
There are other neutralizing MAB that are further along in development.
There are other neutralizing MAB that are further along in development.
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