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Started By
Message
re: New French Study on Hydroxychloroquine/Azithromycin - IT WORKS!!
Posted on 3/28/20 at 9:48 am to Major Dutch Schaefer
Posted on 3/28/20 at 9:48 am to Major Dutch Schaefer
Called my primary care physician last week to see If hydroxychloroquine was available to people who fall into the higher risk demographic, (me) .....was told they weren't prescribing any therapeutic prescriptions because they haven't been advised to do such and was also told much of the supply was being reserved for current COVID19 patients and potentially for healthcare professionals.
My issue with all these pandemic experts claiming the effectiveness of chloroquine is anecdotal is the anecdotal evidence is being presented by other doctors who have been using the drug prior to infections, directly after infections and when patients are deathly ill and it seems to work pretty well. I say to the government get off your asses, make a proclamation through Trump's executive powers to start producing mass doses of the therapeutic protocol of hydroxychloroquine/azithromycin
My issue with all these pandemic experts claiming the effectiveness of chloroquine is anecdotal is the anecdotal evidence is being presented by other doctors who have been using the drug prior to infections, directly after infections and when patients are deathly ill and it seems to work pretty well. I say to the government get off your asses, make a proclamation through Trump's executive powers to start producing mass doses of the therapeutic protocol of hydroxychloroquine/azithromycin
1
Posted on 3/28/20 at 9:48 am to Major Dutch Schaefer
game changer
Posted on 3/28/20 at 9:48 am to MoarKilometers
quote:
Stole this response from the OT...
quote:
Out of the 80 patients, 74 had a low NEWS score, which means they would ordinarily be told not to come to the hospital and instead stay at home and recover. Additionally, only 12 had a fever.
At the end of the study, 1 died, 1 remained in the ICU, and 13 others remain in the hospital. With a 1.5% mortality rate for all positive tests (what we currently see in the US), you would expect an average of 1.2 fatalities for every 80 positive tests.
France has a 6% mortality rate
LINK
Posted on 3/28/20 at 9:48 am to Cosmo
quote:
But once you come in sick as shite with ARDS the damage is already done and you just have to wait it out.
That's where the Remdesivir comes into play is my understanding.
Posted on 3/28/20 at 9:50 am to Major Dutch Schaefer
observational study in pdf(In case folks want to look at it)
https://www.mediterranee-infection.com/wp-content/uploads/2020/03/COVID-IHU-2-1.pdf
https://www.mediterranee-infection.com/wp-content/uploads/2020/03/COVID-IHU-2-1.pdf
Posted on 3/28/20 at 9:51 am to Robin Masters
quote:
France has a 6% mortality rate
What's their mortality rate amongst those who wouldn't have been hospitalized? Kinda why this needs to be a double blind study
Posted on 3/28/20 at 9:51 am to Major Dutch Schaefer
Let's light this candle
Posted on 3/28/20 at 9:52 am to Cosmo
quote:
Anecdotally
Do you even know what that means?
Posted on 3/28/20 at 10:33 am to Robin Masters
quote:
France has a 6% mortality rate
America has a better healthcare system.
Posted on 3/28/20 at 10:52 am to Hopeful Doc
quote:
quote:
France has a 6% mortality rate
America has a better healthcare system.
America is irrelevant in this discussion. The treatment too death rate from ~ 5 down to 1.
I realize it’s a small study but if it can improve outcomes in France, in a lesser healthcare system, then why not here?
This post was edited on 3/28/20 at 10:55 am
Posted on 3/28/20 at 12:30 pm to MoarKilometers
quote:this sounds to me like the right way to start a trial - lowest risk patients first. keep using traditional triage methods on the worst cases until the drug is shown to not have adverse affects on healthy people
Out of the 80 patients, 74 had a low NEWS score, which means they would ordinarily be told not to come to the hospital and instead stay at home and recover. Additionally, only 12 had a fever
Posted on 3/28/20 at 12:32 pm to BobBoucher
quote:under normal conditions. this is a much more urgent situation
The concern was he didn’t do a double-blind study with a placebo. That’s the standard our medical community is used to.
quote:exactly. that's why your previous comment about double blind is off target in this particular situation. in fact, you could even say it's unethical
I’d feel sorry for the chaps that got the placebo.
Posted on 3/28/20 at 12:37 pm to Bass Tiger
quote:but this is just more info and we need all the info we can get as quickly as possible. what people do with the info is where it gets political. dem govs are all of the sudden full of restraint regarding the possibility and reasonable, sensible people are saying it's promising. everyone has to decide for themselves which is a more beneficial response.
pandemic experts claiming the effectiveness of chloroquine is anecdotal is the anecdotal evidence is being presented by other doctors who have been using the drug
i would be willing to bet that even the most hardcore political liberal who tested positive would kick a dem gov to the curb with the quickness if the dr said you need zpack/chloroquine because your chances of death just tripled
Posted on 3/28/20 at 1:27 pm to Major Dutch Schaefer
quote:
Yet, some Governors are banning the use of these drugs.
This is a criminal act. These Gov's should be arrested for endangering the lives of the public at large.
Posted on 3/28/20 at 1:45 pm to Major Dutch Schaefer
We need to all hope and pray that this is confirmed via the trials currently underway in NYC.
There isn't anything else that's going to stop this from getting ugly. That statement is purely based on the math of the growth rate and the number of cases we're currently at.
There isn't anything else that's going to stop this from getting ugly. That statement is purely based on the math of the growth rate and the number of cases we're currently at.
Posted on 3/28/20 at 2:17 pm to bfniii
quote:
The concern was he didn’t do a double-blind study with a placebo. That’s the standard our medical community is used to.
under normal conditions. this is a much more urgent situation
Urgent or not, without a double blind placebo control, or a matched cohort at a non-participating hospital with otherwise similar treatment standards, you just won't know.
Look, there's a reason the FDA requires multiple, large, well-designed, statistically significant positive studies before approving a product for an indication. Because chance is a MFer, especially when everyone is looking for any bit of positive news to grab on to. There's been numerous drugs that show promise in early studies only to fail.
So yes, this deserves more investigation, but no, we shouldn't praise this as a miracle cure just yet.
Posted on 3/28/20 at 2:20 pm to Major Dutch Schaefer
quote:
Yet, some Governors are banning the use of these drugs.
Big Pharma dawg
They want the cure, to stick it up our arse at a hefty price.
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