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Posted on 11/23/21 at 4:29 pm to crazy4lsu
quote:
Nearly 2 years into a pandemic and people can't get basic immunology right
First, I don't think it's a realistic expectation for people (broadly) that are products of our public education system to "get basic immunology" ever - but my overriding point is your profession, its practitioners, organizations and gov't overlords, have failed so miserably at managing the pandemic and articulating rational messages/information about Covid that even if there were 330 million scientists in this country, not a whole lot would be different today.
Posted on 11/23/21 at 4:38 pm to David_DJS
I don't disagree with that at all. In terms of messaging, public health officials have done a terrible job.
No one in the literature can define discretely why immunologic memory wanes, at least that I've seen, or what correlate of adaptive immune response defines long-term immunity. Suggesting that natural infection immunity will wane also misunderstands the differences between other coronaviruses and this one, as immune response is generally more measured in the upper respiratory tract, for good reason, while lower respiratory tract infections generally produce more robust immune response. It isn't a like-for-like comparison, and its utility is very limited, in my view.
No one in the literature can define discretely why immunologic memory wanes, at least that I've seen, or what correlate of adaptive immune response defines long-term immunity. Suggesting that natural infection immunity will wane also misunderstands the differences between other coronaviruses and this one, as immune response is generally more measured in the upper respiratory tract, for good reason, while lower respiratory tract infections generally produce more robust immune response. It isn't a like-for-like comparison, and its utility is very limited, in my view.
Posted on 11/23/21 at 4:51 pm to crazy4lsu
quote:
Lol. Nearly 2 years into a pandemic and people can't get basic immunology right, while insisting they learned it in the 5th grade. Very cool.
Hiroshima was 75 years ago and i bet you still can’t put together a basic nuclear bomb.
Posted on 11/23/21 at 4:54 pm to Rick9Plus
Lol.
Posted on 11/23/21 at 5:29 pm to David_DJS
quote:
that even if there were 330 million scientists in this country, not a whole lot would be different today.
We’d have all starved.
Posted on 11/23/21 at 5:31 pm to Landmass
quote:
Antibodies are not the only piece to immunity. There is also T cell immunity. Once you have a virus and antibodies fade due to not being exposed (exposure is good for the recovered) you may or may not get sick. T cells will recognize the virus, tell the body to make antibodies again and the big mean virus is nothing more than a minor cold.
This is science. I learned this in 5th grade.
For the win!
Posted on 11/23/21 at 5:33 pm to Rick9Plus
quote:
Hiroshima was 75 years ago and i bet you still can’t put together a basic nuclear bomb.
I could if I had enough enriched uranium and 4 million dollars.
Posted on 11/23/21 at 5:34 pm to WeeWee
I wanted to get my $0.02 in. WeeWee, you are as dumb as a liberal commie gets. Go take another shot fool. 
Posted on 11/23/21 at 5:38 pm to WeeWee
63 months
Glad I took out that 72 month loan, now
Glad I took out that 72 month loan, now
Posted on 11/23/21 at 5:43 pm to TideCPA
When we talk about "immunity" from COVID, we need to be sure not to conflate immunity to infection with some degree of protection against hospitalization and death. The vaccines clearly help with the latter but are virtually useless for the former. I got the Pfizer vaccine in April and caught COVID in September, 5 months later. That timeline makes it clear that it's impossible to vaccinate our way out of COVID; it's here to stay.
I agree we are stuck with the CCP virus but I have seen no evidence the vaccines make the CCP virus less dangerous or easier to get over. In fact I have yet to see a reason for a vaccine against the CCP virus.
Given that, the only thing that matters is protection against severe, potentially fatal cases. And evidence shows that both natural infection (and recovery) and vaccination both provide long-term protection against severe illness.
Do you have a link to a peer reviewed study? Just because Fauci blows smoke up your dress does not make it so, speaking of the vaccinations.
At this point, I've had a COVID vaccine and the disease itself. There's no legitimate reason to "boost" anything, because preventing infection is a fool's errand, as it would necessitate shots every few months.
I agree we are stuck with the CCP virus but I have seen no evidence the vaccines make the CCP virus less dangerous or easier to get over. In fact I have yet to see a reason for a vaccine against the CCP virus.
Given that, the only thing that matters is protection against severe, potentially fatal cases. And evidence shows that both natural infection (and recovery) and vaccination both provide long-term protection against severe illness.
Do you have a link to a peer reviewed study? Just because Fauci blows smoke up your dress does not make it so, speaking of the vaccinations.
At this point, I've had a COVID vaccine and the disease itself. There's no legitimate reason to "boost" anything, because preventing infection is a fool's errand, as it would necessitate shots every few months.
This post was edited on 11/23/21 at 5:44 pm
Posted on 11/23/21 at 5:45 pm to WeeWee
quote:
I'm not shitting on herd immunity because it is real thing and very effective. However it does start to wane.
How do you know this? Because the authors INFERRED it?
Posted on 11/23/21 at 5:55 pm to RaginCajunz
quote:
So we're looking at 16 months median vs 5 months?
No. This is the problem. People who are incapable of understanding this are nonetheless opining.
You are comparing two different things. The 16 months is the median time to reinfection for those with natural immunity. The 5 months is the durability of the vaccine. The median time to reinfection for those with vaccine immunity is obviously more than 5 months, though I have no idea how much.
The bigger point here is that this is not based on first order data. They are inferring all kinds of shite, so it’s a wild arse guess on their part.
Why don’t we just wait until folks with natural immunity start dropping like flies? Then we’ll maybe start vaccinating them. Until then, kiss my arse!
Posted on 11/23/21 at 5:58 pm to WeeWee
quote:
You might be think that you are protected and you are actually not and need a booster :gasp:
Quick question
For patients with natural immunity what is their risk of hospitalization or death if they get reinfected?
If you don’t know this why would you recommend vaccination? What benefit will they see after vaccination?
Posted on 11/23/21 at 6:26 pm to WeeWee
quote:
Natural covid immunity does not last forever.
no shite huh?
neither does immunity from the common cold or the flu.
we got ourselves a frickin genius here fellas.
This post was edited on 11/23/21 at 6:31 pm
Posted on 11/23/21 at 6:33 pm to RightHook
not a reply to previous post
My adult son had covid 9 months ago. Felt pretty bad, down for the count but no major problems and was over it in the usual 10 days .
About a week ago he started feeling congested. Felt like he had just an annoying cold. But after several days of this minor cold, he developed pinkeye. Took a test. Positive for covid again. Definitely not as sick as he was the first time around. Got a prescription for his eye. After nothing but congestion and a little fatigue, he's on the mend again.
My adult son had covid 9 months ago. Felt pretty bad, down for the count but no major problems and was over it in the usual 10 days .
About a week ago he started feeling congested. Felt like he had just an annoying cold. But after several days of this minor cold, he developed pinkeye. Took a test. Positive for covid again. Definitely not as sick as he was the first time around. Got a prescription for his eye. After nothing but congestion and a little fatigue, he's on the mend again.
Posted on 11/23/21 at 6:36 pm to WeeWee
Anyone know what the number (magnitude) and units of antibody test results mean, relative to "immunity?"
e.g. xx U/ml
e.g. xx U/ml
Posted on 11/23/21 at 6:52 pm to WeeWee
And what do you suggest that people with Natural Immunity do…..get a jab?
Posted on 11/23/21 at 9:56 pm to ABearsFanNMS
If you are a halfway healthy young adult under 50 with a previous covid infection there is zero need for this vaccine.
Posted on 11/23/21 at 10:54 pm to WeeWee
Booster shots in perpetuity then? A new booster once a month just to be safe? Of course the government will have to pay for them since these viruses will affect women and minorities the worst. While we're at it, we'll just let the state assume control of ALL health care.
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