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Started By
Message
PSA: Fasting is good for health/longevity (IF and Keto Krewe)
Posted on 10/6/16 at 8:22 am
Posted on 10/6/16 at 8:22 am
youtube
podcast
Valter Longo, Ph.D. on Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis
In this conversation, Rhonda and Valter discuss...
• The effects of prolonged fasting, which refers to 2-3 day fasting intervals in mice and 4-5 days in humans.
• Dr. Longo’s work on the fasting-mimicking diet, which is 5 day restricted diet that is meant to simulate some of the biological effects of prolonged fasting while still allowing some food.
• How clinical trials have demonstrated efficacy for this diet for type 2 diabetes, multiple sclerosis, and cancer patients.
• Fasting as an inducer of differential stress resistance, where it can simultaneously make cancer cells more sensitive to death while also making healthy cells more resistant to these same death stimuli (such as chemotherapy) which might otherwise induce cell death amongst healthy cells as collateral damage.
• Fasting as a biological state which humans historically experienced with extreme regularity and we may ultimately need in order to mitigate various disease states.
• The effects of prolonged fasting on the immune system, namely, how it clears away damaged white blood cells via autophagy and how this causes hematopoietic stem cells to self renew and make more stem cells and also produce new blood cells to fully replenish the white blood cell population.
• How prolonged fasting causes a shift in the immune cell population towards one that is more representative of youth by normalizing the ratio of myeloid cells to lymphoid cells.
• The positive effects of prolonged fasting and the fasting-mimicking diet on markers of systemic inflammation, blood glucose levels and other aging biomarkers.
• The conclusions of Dr. Longo & Dr. Marcus Bock’s research comparing 1 week of the fasting-mimicking diet followed by 6 months of mediterranean diet to six months of a ketogenic diet in people with multiple sclerosis.
• The strange, somewhat paradoxical role of autophagy genes in cancer progression and some of the open questions surrounding the exact role that these genes are playing.
• Dr. Longo’s high level thoughts on metformin as an anti-aging drug.
• How the growth hormone/IGF-1 axis is one of the most important genetic pathways in aging from yeast to worms to mice to humans.
Very important implications and the "therapy" is free....
Cannot stay and play....
podcast
Valter Longo, Ph.D. on Fasting-Mimicking Diet & Fasting for Longevity, Cancer & Multiple Sclerosis
In this conversation, Rhonda and Valter discuss...
• The effects of prolonged fasting, which refers to 2-3 day fasting intervals in mice and 4-5 days in humans.
• Dr. Longo’s work on the fasting-mimicking diet, which is 5 day restricted diet that is meant to simulate some of the biological effects of prolonged fasting while still allowing some food.
• How clinical trials have demonstrated efficacy for this diet for type 2 diabetes, multiple sclerosis, and cancer patients.
• Fasting as an inducer of differential stress resistance, where it can simultaneously make cancer cells more sensitive to death while also making healthy cells more resistant to these same death stimuli (such as chemotherapy) which might otherwise induce cell death amongst healthy cells as collateral damage.
• Fasting as a biological state which humans historically experienced with extreme regularity and we may ultimately need in order to mitigate various disease states.
• The effects of prolonged fasting on the immune system, namely, how it clears away damaged white blood cells via autophagy and how this causes hematopoietic stem cells to self renew and make more stem cells and also produce new blood cells to fully replenish the white blood cell population.
• How prolonged fasting causes a shift in the immune cell population towards one that is more representative of youth by normalizing the ratio of myeloid cells to lymphoid cells.
• The positive effects of prolonged fasting and the fasting-mimicking diet on markers of systemic inflammation, blood glucose levels and other aging biomarkers.
• The conclusions of Dr. Longo & Dr. Marcus Bock’s research comparing 1 week of the fasting-mimicking diet followed by 6 months of mediterranean diet to six months of a ketogenic diet in people with multiple sclerosis.
• The strange, somewhat paradoxical role of autophagy genes in cancer progression and some of the open questions surrounding the exact role that these genes are playing.
• Dr. Longo’s high level thoughts on metformin as an anti-aging drug.
• How the growth hormone/IGF-1 axis is one of the most important genetic pathways in aging from yeast to worms to mice to humans.
Very important implications and the "therapy" is free....
Cannot stay and play....
10
Posted on 10/6/16 at 8:35 am to ThinePreparedAni
quote:
Fasting for Longevity, Cancer & Multiple Sclerosis
Why would you want to fast for cancer and MS? I don't want either of those things.
Posted on 10/6/16 at 8:36 am to ThinePreparedAni
Somebody hand me another snickers.
Posted on 10/6/16 at 8:56 am to ThinePreparedAni
So it talks about fasting 4-5 days at a time? How often are they promoting fasting that long of a period?
That's a long fricking time. I expected this to be about IF.
That's a long fricking time. I expected this to be about IF.
Posted on 10/6/16 at 9:01 am to TigerFanatic99
A buddy of mine looked into this and did it.
There are fasting clinics. He did it on his own. Allowing water of course. He made it about 20 days? It cleanses the system and you start over. So say the fasters?
Toward the end he looked miserable. BP lower and HR lower. Of course dying does that too...?
There are fasting clinics. He did it on his own. Allowing water of course. He made it about 20 days? It cleanses the system and you start over. So say the fasters?
Toward the end he looked miserable. BP lower and HR lower. Of course dying does that too...?
Posted on 10/6/16 at 9:02 am to ThinePreparedAni
I'm calling bullshite
Posted on 10/6/16 at 9:09 am to TigerFanatic99
quote:
So it talks about fasting 4-5 days at a time? How often are they promoting fasting that long of a period? That's a long fricking time. I expected this to be about IF.
Bimonthly
And it's not total fasting it said they took in 40-50% of their normal calories for that period.
Posted on 10/6/16 at 9:11 am to TigerFanatic99
quote:
So it talks about fasting 4-5 days at a time? How often are they promoting fasting that long of a period?
I'd like to know too. It did mention the initial fast followed by 6 months of the Mediterranean diet, followed by another 6 months of the keto diet. But I think that was specifically for MS or something.
I haven't read too much about IF, but I did read about this doctor(maybe Phd not MD, I can't remember) who advocated fasting as part of a healthy lifestyle. He is a Christian-Jew and also incorporated some of the old-testament laws on food which are a bit too extreme for me(no pig or shellfish for example), but I was intrigued by the suggestion of a day of fasting once a week. I don't remember reading the science behind how it may affect your metabolism--it may just aid by helping digestion and not taking in those 2,000 or so calorie once a week.
Posted on 10/6/16 at 9:11 am to ThinePreparedAni
There's also studies that suggest no ejaculation can lead to elongated life spans, but where's the fun in that?
Longevity does not equal thriving/happiness.
I'd rather eat well, wreck shite, and die suddenly at 75 than linger around till I'm 90 as an emaciated shell.
Longevity does not equal thriving/happiness.
I'd rather eat well, wreck shite, and die suddenly at 75 than linger around till I'm 90 as an emaciated shell.
This post was edited on 10/6/16 at 9:12 am
Posted on 10/6/16 at 9:15 am to LSUfan20005
quote:
There's also studies that suggest no ejaculation can lead to elongated life spans, but where's the fun in that?
Longevity does not equal thriving/happiness.
I'd rather eat well, wreck shite, and die suddenly at 75 than linger around till I'm 90 as an emaciated shell.
Roger that. I agree.
There can be a balance where this is blended in occasional. Ancient cultures/religions have been doing this for generations...
The info does have applications for those who may be at different stations in life.
Posted on 10/6/16 at 9:23 am to ThinePreparedAni
quote:
ThinePreparedAni
I see what you did there.
Anybody ever read the book "Blue Zones"(?). I saw the author on Bill Maher, I think, a couple years ago. He studied the places in the world where people live the longest and their diets. Seems like most led very active lives into their 80s and 90s. Not shocking, but I'm pretty sure they all walked a lot and ate a primarily fruit/vegetable based diet, probably similar to Mediterranean.
Posted on 10/6/16 at 9:30 am to ThinePreparedAni
Fasting is a part of a healthy existence. It's in the original OTL where all great points of wisdom are found.
Posted on 10/6/16 at 9:41 am to ThinePreparedAni
I do at least one 18-20 hour fast per week. I do 12 hour fast nearly every day. (skip breakfast, just black coffee and water until lunch)
Posted on 10/6/16 at 9:41 am to ThinePreparedAni
quote:
Fasting is good for health/longevity
or just workout where the torture on your body is actually fun
Posted on 10/6/16 at 9:48 am to ThinePreparedAni
I've done IF for extended periods of time. I felt great and had pretty incredible weight loss. I'm 5'9 and the first time I started I was down from about 165 to 145 in a month.
The first two weeks are pretty difficult, but after that there is no hunger outside of your feasting window. Certainly not torture like the poster above thinks
The first two weeks are pretty difficult, but after that there is no hunger outside of your feasting window. Certainly not torture like the poster above thinks
This post was edited on 10/6/16 at 9:50 am
Posted on 10/6/16 at 9:49 am to ThinePreparedAni
I just spit up my frosty reading this shite
The hell this shite about?
Cliffs?
The hell this shite about?
Cliffs?
Posted on 10/6/16 at 9:53 am to joshnorris14
quote:
The first two weeks are pretty difficult, but after that there is no hunger outside of your feasting window. Certainly not torture like the poster above thinks
Roger that.
I am 6'2 230 and lift lots of heavy shite while doing this....
Posted on 10/6/16 at 9:55 am to tankyank13
quote:Fast or die. It's from the Bible.
The hell this shite about? Cliffs
Where in the hell do you think they came up with the Quick and the Dead?
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