re: Pfizer’s CEO Hasn’t Gotten His Covid Vaccine Yet, Say He Doesn’t Want To Cut In Line!

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mRNA technology has advanced far beyond that article in just the last 2 years.

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Source?

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Yet you will probably buy street tacos cooked by a gross guy in a dirty van

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because that’s the same as a first run vaccine

(no message)

I don’t know how anyone could read that article and not come away with the confidence that mRNA vaccines are safer than DNA vaccines

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However we have no answer to the autoimmune question because we can’t have long term data and until we are years down the road.

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We also don’t know the long term effects of covid.

I’m not very concerned but you could speculate many different things 5-10 years down the road. Can you get it again and it be worse? Can successive infections lead to compounding lung damage?

It’s not like there’s an option that’s free of risk

We also can’t have long term data on COVID.

Statistically, both are low risk for most people.

This seems to be what you are worried about in that article:

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Several different mRNA vaccines have now been tested from phase I to IIb clinical studies and have been shown to be safe and reasonably well tolerated (TABLES 2,?,3).3). However, recent human trials have demonstrated moderate and in rare cases severe injection site or systemic reactions for different mRNA platforms22,91. Potential safety concerns that are likely to be evaluated in future preclinical and clinical studies include local and systemic inflammation, the biodistribution and persistence of expressed immunogen, stimulation of auto-reactive antibodies and potential toxic effects of any non-native nucleotides and delivery system components. A possible concern could be that some mRNA-based vaccine platforms54,166 induce potent type I interferon responses, which have been associated not only with inflammation but also potentially with autoimmunity167,168. Thus, identification of individuals at an increased risk of autoimmune reactions before mRNA vaccination may allow reasonable precautions to be taken. Another potential safety issue could derive from the presence of extracellular RNA during mRNA vaccination. Extracellular naked RNA has been shown to increase the permeability of tightly packed endothelial cells and may thus contribute to oedema169. Another study showed that extracellular RNA promoted blood coagulation and pathological thrombus formation170. Safety will therefore need continued evaluation as different mRNA modalities and delivery systems are utilized for the first time in humans and are tested in larger patient populations.

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Note it says “possible concern.” Didnt say it had actually panned out.

Also looked at those tables and all those trials were in stage 1/2 with apparently pretty small sample sizes (i didnt delve into the subject numbers of each trial)

The sample sizes for current covid vaccines are pretty big and they have had a couple years to play with delivery systems.

Dont get the vaccine if you dont want to. But the fact that 90% of our docs are getting the pfizer vaccine in the next couple weeks should tell you something (every damn one of our ID docs is getting the vaccine and they understand the vaccines better than I do)

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Don’t be such a combative dick. I’m legitimately looking for reasons to take the vaccine. Provide me with resources. Not just a logical fallacy appeal to authority.

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To be fair, as others have already stated, you’re worried about an unknown potential risk of the vaccine without considering any unknown potential risks of Covid-19.

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TulaneLSU

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Friend,

We could call it the RICKEY (R for rhinovirus, I for influenza, and C for coronavirus). I would be first in line next to you, but at least six feet away.

Yours,
TulaneLSU