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re: FDA panel says common over-the-counter decongestant doesn’t work

Posted on 9/12/23 at 3:22 pm to
Posted by Lsuhoohoo
Member since Sep 2007
94559 posts
Posted on 9/12/23 at 3:22 pm to
quote:

A key ingredient in many over-the-counter cold and allergy medications called phenylephrine doesn’t work to get rid of nasal congestion, a Food and Drug Administration advisory panel concluded Tuesday.


quote:

Phenylephrine gained popularity in the early 2000s as a replacement for pseudoephedrine, the decongestant used in Sudafed, which was moved behind the pharmacy counter in 2006 in an attempt to curb its misuse as an ingredient to make methamphetamine.



Were from the government and were here to help.
Posted by S1C EM
Athens, GA
Member since Nov 2007
11585 posts
Posted on 9/12/23 at 3:24 pm to
quote:

Goddamn, the university research team proved that phenylephrine doesn't work any better than a placebo, and still you guys persist.


So I should ignore my real-world experience in favor of a university research team who, just now, came to the conclusion that phenylephrine does nothing? Okay, sure.

quote:

You're just like the blockheads which thought phenylephrine could be used to create meth, and that's why it's being pulled.


Uh, nah. That ain't me.

quote:

The news outlet notes that the researchers previously pressed the FDA to remove phenylephrine products back in 2007 but the agency rebuffed them.



quote:

FDA doin work on behalf of the citizens. As usual.


You being facetious or are you confused?
This post was edited on 9/12/23 at 3:29 pm
Posted by THog
Member since Dec 2021
2226 posts
Posted on 9/12/23 at 3:25 pm to
Wonder is phenylephrine could be a therapeutic for the next pandemic?
Posted by Duckhammer_77
TD Platinum member
Member since Nov 2016
2687 posts
Posted on 9/12/23 at 3:55 pm to
Pseudoephedrine + Prednisone
= OTC cocaine
Posted by deltaland
Member since Mar 2011
90711 posts
Posted on 9/12/23 at 4:00 pm to
And the nasal sprays if used too much can damage your nose similar to cocaine use
Posted by dgnx6
Baton Rouge
Member since Feb 2006
68700 posts
Posted on 9/12/23 at 4:18 pm to
Trust government and the medical community.

Posted by GumboPot
Member since Mar 2009
118862 posts
Posted on 9/12/23 at 4:38 pm to
quote:

The unanimous vote, which specifically declared oral formulations of phenylephrine ineffective


My go to for daytime relief when I have colds is Mucinex-D.

The active ingredients are guaifenesin and pseudoephedrine (which is phenylephrine).

I hope the FDA doesn't pull phenylephrine form OTC.
Posted by GumboPot
Member since Mar 2009
118862 posts
Posted on 9/12/23 at 4:39 pm to
quote:

And the nasal sprays if used too much can damage your nose similar to cocaine use



Don't use too much.
Posted by roux
Tiger Territory
Member since Dec 2006
1591 posts
Posted on 9/12/23 at 4:40 pm to
But the vaccine works.... sure
Posted by bad93ex
Member since Sep 2018
27262 posts
Posted on 9/12/23 at 4:41 pm to
quote:

The active ingredients are guaifenesin and pseudoephedrine (which is phenylephrine).



They are not the same thing
Posted by DiamondDog
Louisiana
Member since Nov 2019
10579 posts
Posted on 9/12/23 at 4:43 pm to
quote:

The panel’s vote reflects damning evidence provided by the FDA that found that when phenylephrine is taken orally,


This does not apply to the nose spray.
Posted by GumboPot
Member since Mar 2009
118862 posts
Posted on 9/12/23 at 4:50 pm to
quote:

quote:

The active ingredients are guaifenesin and pseudoephedrine (which is phenylephrine).



They are not the same thing


I had to look it up. You're right. Pseudoephedrine is missing the little OH group on the benzene ring versus phenylephrine.
Posted by tigafan4life
Member since Dec 2006
48924 posts
Posted on 9/12/23 at 4:59 pm to
Well no shite. It ain’t the real Sudafed.
Posted by slackster
Houston
Member since Mar 2009
85010 posts
Posted on 9/12/23 at 7:19 pm to
quote:

This is true however phenylephrine works for many including myself. It isn't as strong as pseudoephedrine and why I will recommend it to folks that can't tolerate the stronger effects. Its also preferred in some because it doesn't send blood pressure up as much. Whatever, I guess. I'll still recommend it to certain patients regardless of what the FDA states.


How about the actual research that says it doesn’t work?
Posted by sleepytime
Member since Feb 2014
3584 posts
Posted on 9/12/23 at 7:50 pm to
Phenylpropanolamine worked great with fewer side effects than ephedrine or pse. It was banned because a handful of people with silent heart conditions died over a 20 year period from taking it.
Posted by cubsfan5150
Member since Nov 2007
15777 posts
Posted on 9/12/23 at 8:09 pm to
You’ve read the research?

I thought I read that roughly 10% actually makes it to the nasal area. Maybe that’s all some need to feel relief?
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