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Message

re: Drug Prices (Pharmaceutical)

Posted on 10/14/18 at 6:23 pm to
Posted by CLane33
Member since Sep 2016
478 posts
Posted on 10/14/18 at 6:23 pm to
Posted by CoachDon
Louisville
Member since Sep 2014
12409 posts
Posted on 10/14/18 at 6:29 pm to
My kids have nut allergies, have to have Eli pens on hand. Price skyrocketed after 2007 to over $600
Posted by East Coast Band
Member since Nov 2010
66988 posts
Posted on 10/14/18 at 6:55 pm to
quote:

You know how much money it costs to research and develop these drugs?

You left out how it costs to send the sales reps to the Bahamas twice a year.
Posted by junior
baton rouge
Member since Mar 2005
2700 posts
Posted on 10/14/18 at 7:22 pm to
quote:

I'm sure it wasn't as easy as just 1 + 1 equals two. And profits today as fuel research for tomorrow. Can some costs be cut, I'm sure they can, but it's not some scam either.



It is exactly that easy. 800mg ibuprofen + 26.6mg Pepcid . I’m sure the 26.6 is just so they can say it’s not the same as the 20mg you can get over the counter.

Generic Lamisil 10$ for 100 pills. Name brand? nearly 2000$- what’s the difference in production costs- zero. Why the difference? Some people will have the insurance pay and they don’t care or know the price difference.

Pharmaceutical companies have paid generic producers to stop producing drugs. Why? It takes a while to get the generic drug in the pipeline. If 2weeks before a drug goes off patent, big pharm pays the 1-3 generic drug companies who are in production to stop, they can easily cover their costs on their profits.

They aren’t “evil” (probably) they are just making money for their company, but our government needs to change the laws to encourage free market pricing. Also, health care is different. A cardiologist can’t just tell a patient in the ER who’s having a heart attack thats he’s charging 1,000,000 for a life saving procedure, but that’s kind of what’s big pharm is doing. We need new laws.
Posted by Stateguy
Baton Rouge
Member since Dec 2006
972 posts
Posted on 10/14/18 at 8:08 pm to
quote:

Epi pens on hand. Price skyrocketed after 2007 to over $600


This is the worst part to me. This didn't suddenly become expensive to make. They supposedly didn't raise prices for about 10 years

Aggravating to me that insulin analogs available 10 years ago (humalog, novolog, lantus) have prices that have gone up so much. Insulins are relatively expensive to make but the price increase far exceeds inflation/production costs.

Also - most of the meds originally listed don't cost patients that much. Those were list prices.
Posted by Mingo Was His NameO
Brooklyn
Member since Mar 2016
37536 posts
Posted on 10/14/18 at 8:13 pm to
quote:

Generic Lamisil 10$ for 100 pills. Name brand? nearly 2000$- what’s the difference in production costs- zero


quote:

Why the difference?


One paid tens to hundreds of millions to develop the product and the other read it off a price of paper when the patent expired
Posted by junior
baton rouge
Member since Mar 2005
2700 posts
Posted on 10/14/18 at 8:27 pm to
quote:

One paid tens to hundreds of millions to develop the product and the other read it off a price of paper when the patent expired


The first maker (Novartis for Lamisil) gets a 20 year monopoly. That should be more than enough to recoup their costs and still make billions in profits (they made 1.2 billion in 2004 alone)
Posted by junior
baton rouge
Member since Mar 2005
2700 posts
Posted on 10/14/18 at 8:39 pm to
Canada vs US price?

quote:

7.)Latuda, bipolar disorder, 30 tablets, $1500


Prices vary depending on dosing, but Typically less than $500
Posted by Mingo Was His NameO
Brooklyn
Member since Mar 2016
37536 posts
Posted on 10/14/18 at 8:58 pm to
quote:

The first maker (Novartis for Lamisil) gets a 20 year monopoly. That should be more than enough to recoup their costs and still make billions in profits (they made 1.2 billion in 2004 alone)


Sure but what about the tens of millions they need to develop the next drug that could save lives? Where is that going to come from? They fund R&D through current sales, it's not that complicated.

In a way you are buying medicines that don't exist yet as much as you are purchasing the pills that cost tenths of a cent to make now.
Posted by HogsInTheRock
ARKANSAS
Member since Nov 2004
632 posts
Posted on 10/14/18 at 9:22 pm to
Diclegis for morning sickness = pyridoxine (vitamin B6) + doxylamine (OTC sleep aid)


Prescription Diclegis (10 mg pyridoxine/10 mg doxylamine) costs around $570 for 100 tablets. Many patients may require two to four tablets per day. Over-the-counter 25 mg pyridoxine and 20 mg doxylamine each cost $5 to $10 for 100 tablets.Jan 4, 2015


Yeah but they spent $1B on R&D yeahhh buddy
Posted by Mingo Was His NameO
Brooklyn
Member since Mar 2016
37536 posts
Posted on 10/14/18 at 9:23 pm to
quote:


Yeah but they spent $1B on R&D yeahhh buddy


Is that not relevant in pricing models?
Posted by WildcatMike
Lexington, KY
Member since Dec 2005
44393 posts
Posted on 10/14/18 at 9:43 pm to
quote:

A lot of those costs are funded by taxpayer dollars in the form of research grants.


That is not how that works.
Posted by junior
baton rouge
Member since Mar 2005
2700 posts
Posted on 10/15/18 at 4:29 am to
Drug maker Valeant was a small from that showed the rest what to do. It would buy a larger company, raise prices and drastically cut research funding. It would make big profits, and repeat. Yes, they pushed too hard and got the ban hammer, but the same thing still continues with other companies. (Not many new drug are coming out of those companies. It’s ok, they will just buy another.)

Our government definitely pays billions to support new drugs. Any LSU fans hear of Pennington?

Finally, cudos to Mingo. I thought you must be a drug rep at first, but now I see I’ve been trolled.
Posted by The Hamburglar
McDonaldland
Member since Jan 2005
3355 posts
Posted on 10/15/18 at 4:39 am to
quote:

The first maker (Novartis for Lamisil) gets a 20 year monopoly


Assuming you are referring to patent life - I note the 20 years is from first date of filing the application, not from issuance or first instance of commercialization. Many drugs only have a decade of commercialization monopoly, if that.
Posted by Volvagia
Fort Worth
Member since Mar 2006
53591 posts
Posted on 10/15/18 at 5:13 am to
quote:

The cost isn't in producing them


Ehhhhhhhhhh

Sometimes

Stereoisomers can be an absolute bitch to limit, isolate, and purify.
This post was edited on 10/15/18 at 5:16 am
Posted by Tarps99
Lafourche Parish
Member since Apr 2017
13391 posts
Posted on 10/15/18 at 6:42 am to
Here is my hunch and I could be wrong...

High Drug prices are because of number of reasons which include but are not limited to: Medicare Part D, Medicaid, Doctors, and insurance.

Medicare part D has hole where the patients have to pay nearly the full costs of drugs until you get to a certain annual max. So if you are XYZ Drug Company, you price your drug above this price and the client goes straight to the max and client gets a subsidized rate from the government while the government picks up the rest.

Medicaid is listed for the obvious reason, someone else is paying for it and usually at no copay cost to the user. I have seen Children’s cough medicine in a retail package be given as a prescription.

Doctors are part of the problem too as they may prescribe a certain drug that may be on the shelf as over the counter in a certain dose, but be available as a prescription in another. For example, my dad at a time was prescribed Zyrtec in a 5 mg dose. But you can’t buy 5mg over the counter, or it had to be ordered and it costs extremely more than what is sold the over the counter.

Insurance same as above reasoning, except that there is a copay involved with some added contracts in regards to pricing.

The health care and insurance models have to change to be more realistic of the prices and what is the true cost. But no one wants to do that, they want to continue to try to game each other until one gets caught or called out on their extremely high prices.
Posted by ksayetiger
Centenary Gents
Member since Jul 2007
70469 posts
Posted on 10/15/18 at 7:06 am to
[uote]One of the biggest markets of them all is diabetes.
[/quote]

Insulin's patent was supposed to expire recently, allowing generic forms to be manufactored.

Yeah right. That was blocked.

To add to this:

quote:

5-pack of Novalog flex pens (about a months worth of fast acting insulin) is nearly $1300. And most people have that paired with a longer acting insulin such as Lantus or similar (also in the 5-pk of pens at a similar price).




I use an insulin pump, I get insulin by the vial. At cost is 250/vial, (i should call them and tell them to jack it up 100, amirite?)
Posted by crap4brain
Louisiana
Member since Sep 2004
2689 posts
Posted on 10/15/18 at 7:12 am to
Thank the lawyers for a lot of the cost. "Have you or someone you know ever taken any pharmaceuticals? You may be entitled to huge compensation"
Posted by lake chuck fan
Vinton
Member since Aug 2011
24897 posts
Posted on 10/15/18 at 8:52 am to
quote:

The alternative is for them not to exist because they aren't economically feasible.


Agreed, R/D cost is substantial... but these super pharma corps. make insane profits. Pharma market is such, they set their own price using lobbyist in Washington (FDA) to pay their way. We are at their mercy.
Posted by dfintlyHmmrd
Jigga City
Member since Dec 2016
1408 posts
Posted on 10/15/18 at 9:12 am to
quote:

That is not how that works.


That is 100% how it works, a ton of these drugs are partially developed or come out of research done at universities funded by taxpayer grants.
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