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re: Could someone OD on pot?
Posted on 9/12/18 at 6:20 am to theantiquetiger
Posted on 9/12/18 at 6:20 am to theantiquetiger
imho,it would render you into the best night's sleep of your life,when the THC reached a level your body couldn't function on.
I don't know of anyone ever ingesting that much.
I've seen a couple of people get too high off the Bud that's out there now.They thought something was wrong.An anxiety attack,probably.
I don't know of anyone ever ingesting that much.
I've seen a couple of people get too high off the Bud that's out there now.They thought something was wrong.An anxiety attack,probably.
Posted on 9/12/18 at 7:32 am to theantiquetiger
No.
You might think that [RACIALLY INSENSITIVE NOUN - REDACTED] is dead, but he ain't dead. He's gonna wake up in half an hour, and eat eve-erything.
You might think that [RACIALLY INSENSITIVE NOUN - REDACTED] is dead, but he ain't dead. He's gonna wake up in half an hour, and eat eve-erything.
Posted on 9/12/18 at 10:19 am to northshorebamaman
Yes, just stirred the pot into the brownie mix and put it in the oven. We had done it before, albeit with a much smaller amount and it resulted in a pleasurable and enjoyable high. But using an ounce, we overdid it by a mile. Keep in mind this was mid-90's and while the weed was pretty good by the standards back then, it likely was weak sauce compared to what is on the market today. I haven't smoked enough to even qualify as an user in the last 15 years so only going off hearsay as to how powerful the stuff available today is.
Posted on 9/12/18 at 10:23 am to tidalmouse
quote:
I've seen a couple of people get too high off the Bud that's out there now.They thought something was wrong.An anxiety attack,probably.
I made a batch of green dragon for a concert once. Used it to make drinks for a bunch of folks. They all pussed out, so I drank all of it. I normally have a high tolerance, I take about 10-15 hits off pens to get high. But that is most I have ever been high. Concert was at 4, I was still baked the next day when I woke up
Posted on 9/12/18 at 10:28 am to OysterPoBoy
You are a complete dumbass.
Posted on 9/12/18 at 10:34 am to theantiquetiger
the scientific take that I remember said you'd have to smoke a joint the size of a telephone pole in under an hour to OD on pot.
Posted on 9/12/18 at 11:03 am to colorchangintiger
According to Jjdoc who claims to be a physician there are hundreds of fatal marijuana overdoses yearly.
I wish I could find that thread.
Posted on 9/12/18 at 11:09 am to mouton
I smoke everyday. No overdoses here.
Posted on 9/12/18 at 11:15 am to theantiquetiger
quote:
Could someone OD on pot?
I od'd on pot last night. Last thing I remember is crushing a bowl of Raisin Bran Crunch before the lights went out.
Luckily, I woke up this morning. I'm looking for help though. I know it's not good for me to pass out without brushing all that processed sugar out of ma teeth.
Posted on 9/12/18 at 11:33 am to mouton
Found it! It was him and mbutterfly.
LINK
quote:
It was few less than 300 overdose deaths in 2014.
quote:
Thats not true buckeye. T40.7 is for cannabis, but you you set the system up for deaths, you get a little less than 300 due to cannabis posioning.
quote:
That system has every death in the USA listed along with the cause.
LINK
Posted on 9/12/18 at 11:38 am to theantiquetiger
Yes. Look at that kid at LSU. He mixed marijuana and alcohol and died
Posted on 9/12/18 at 12:19 pm to theantiquetiger
It's not identified in humans, but the LD50 (dose that kills 50% of rats that get it) is about 1g/kg (between 800mg and 1200mg) in an oral formulation, meaning about 80 grams in a 180-pounder, though no one has directly reported the effects of such a dose on a human.
They also looked at the IV dose required, which was about 40mg/kg- (about 32g in a 180-pound). This is, of course, impractical, as no one injects marijuana, much less 30g of the THC component of it.
For whatever reason, I'm having difficulty deciphering what they attempt to call the inhalational dose, it's probably in the full text but not in the abstract, but with most things, smoking/inhalational methods are difficult to establish but run somewhere between the oral and IV dose (lungs give an arterial distribution to the inhaled substance without first-pass liver detoxification of that substance, so you assume if it's 100% absorbed in lung and GI tracts that the lung route is a bit closer to the IV route, depending on how much is metabolized by the liver. I'll admit ignorance to the topic, but Bioavailability seems to be about 4-12% in the GI tract depending on absorption and about 30% of the dose in a joint, assuming the joint is about 3.5% (if you notice all the assumptions, it points out "real world" differences will be highly variable based on a fair number of variables))
Abstract below. Did not read full text
gotta run, but fun topic. Basically real-world doses won't kill you
They also looked at the IV dose required, which was about 40mg/kg- (about 32g in a 180-pound). This is, of course, impractical, as no one injects marijuana, much less 30g of the THC component of it.
For whatever reason, I'm having difficulty deciphering what they attempt to call the inhalational dose, it's probably in the full text but not in the abstract, but with most things, smoking/inhalational methods are difficult to establish but run somewhere between the oral and IV dose (lungs give an arterial distribution to the inhaled substance without first-pass liver detoxification of that substance, so you assume if it's 100% absorbed in lung and GI tracts that the lung route is a bit closer to the IV route, depending on how much is metabolized by the liver. I'll admit ignorance to the topic, but Bioavailability seems to be about 4-12% in the GI tract depending on absorption and about 30% of the dose in a joint, assuming the joint is about 3.5% (if you notice all the assumptions, it points out "real world" differences will be highly variable based on a fair number of variables))
Abstract below. Did not read full text
quote:
In order to resolve the differences in reported LD50 values for ?9-tetrahydrocannabinol (?9-THC) obtained with various vehicles and rat strains, the oral LD50 values of ?9-THC in a natural vegetable oil vehicle and in an aqueous emulsion were determined in the same rat strain. In addition an iv LD50 value obtained with the emulsion formulation was compared with an inhalation LD50. The natural vegetable oil was pure sesame oil and the aqueous emulsion used orally was comprised of 13% sesame oil, 1% polysorbate 80 and isotonic saline. A similar emulsion (7% sesame oil and 0.5% polysorbate 80) was used to establish the iv and ip LD50 values. The young adult Fischer rat was used in all experiments and the polysorbate 80 concentration in emulsion formulations was maintained below toxic levels for the rodent. Marihuana cuttings were impregnated with ?9-THC and formed into cigarettes which were smoked under controlled conditions of puff volume and duration in an automatic smoking machine to obtain an inhalation LD50. It was demonstrated that behavioral and physiological responses to ?9-THC occurred sooner with the oral emulsion formulation than with the vegetable oil. The intragastric LD50 with the emulsion was 800 mg/kg and with the sesame oil formulation, 1270 mg/kg. The iv LD50 was 36–40 mg/kg, similar to the inhalation dose when the latter was corrected for ?9-THC losses in the rodent nasal passages. The results from this study affirmed that the LD50 values obtained were reliable and that the vehicle did not contribute to the toxicity. Inhalation, parenteral and oral LD50 values of ?9-tetrahydrocannabinol in Fischer rats. Available from: LINK [accessed Sep 12 2018].
gotta run, but fun topic. Basically real-world doses won't kill you
Posted on 9/12/18 at 12:35 pm to el Gaucho
quote:
Yes. Look at that kid at LSU. He mixed marijuana and alcohol and died
They don’t want to have an honest conversation. Anyone who challenges their belief that everyone should be smoking pot all day is called an idiot and doesn’t understand the world today.
Posted on 9/12/18 at 12:43 pm to OysterPoBoy
I am fine with having an honest conversation. If used recreationally marijuana is fairly safe. Do you disagree?
Posted on 9/12/18 at 12:44 pm to theantiquetiger
I had a roommate in college that certainly tested the limits. If he didn't OD, no one can.
Posted on 9/12/18 at 12:46 pm to OysterPoBoy
OysterPoBoy you said "yes it happens everyday" in response to the op asking if you OD on pot. I am pretty sure he meant a fatal overdose. You aren't claiming people have fatal overdoses on marijuana I assume right?
Posted on 9/12/18 at 12:48 pm to mouton
quote:
If used recreationally marijuana is fairly safe
As long as you aren’t driving sure. So are pain killers. The problem is that recreational use becomes addiction.
Posted on 9/12/18 at 12:52 pm to brett randall
quote:
You’re going to embarrassed when you realize your too stupid to get the joke
When one calls another poster stupid or retarded it is best to make sure you have not made a grammatical error in the self same post.
As for pot. OF COURSE you can OD on pot. You can OD on oreos. Doesn't mean an OD is going to kill you or anything , just means you overdosed.
Posted on 9/12/18 at 1:01 pm to OysterPoBoy
quote:
The problem is that recreational use becomes addiction.
How would you define marijuana addiction? Do you think pain killers used recreationally or as safe as marijuana?
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