How to invest $25K safely for 6 months but still get good return?

Put it in a promotional high interest checking account if you can still find one, nothing safe, short term and has good return

You will need that money to be liquid, short term and without any risk. Put it in your checking/saving and collect your .05%

Can't be done. Bank CDs pay 1% or so. Anything more is going to have some risk of principal loss.

There's no free lunch or reward without risk.

Vanguard Wellesley Fund

40/60 stock/bond mix. Nice quarterly dividend.

open a high-yield savings account or no penalty cd with ally bank.

You will get ~0.85%

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safely for the next 6 months but still earn a good return?

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As others have noted, you can't really. The problem is that rates generally are so low right now that in order to get that kind of rate you'll have to take some risks, usually in the form of a bond that could go up or down.

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borrowing about $50K from my 401(K)

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Why from your 401? That usually isn't a great idea for several reasons, one being that you are borrowing pretax money and repaying post-tax.

the only thing I can think of for your situation is to buy high quality munis that are callable, and are in the call period but haven't been called yet. they trade at par but can have coupons of 3 or 4% and even 5% and trade in small amounts....the risk is that they can get called at any point 90 days out but since they trade at par you wont lose principal but could lost out on transaction costs...our bond desk buys these all the time however, they are hard to find but they do trade, but you have to look for them....