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Ketogenic diet can lead to T2D remission
Posted on 1/28/25 at 8:33 am
Posted on 1/28/25 at 8:33 am
A study done by Virta Health published back in October shows a ketogenic diet can lead to long term T2D remission without medications. A radical idea a few years seems like an obvious idea now.
Keto study
As a 3 year Virta patient I can vouch for the results. I've mentioned my transformation here previously and it's quite amazing. down 80lbs, a1c from 12.4 to 5.5. Stop eating processed food, no sugar, no carbs and lift weights at least 3 days a week. The only medication I've ever taken was metformin.
Here's the highlights:
20% of participants achieved diabetes remission according to international consensus criteria (HbA1c < 6.5% for at least three months without medication).
32.5% of participants reached diabetes reversal (HbA1c < 6.5% without medication or with metformin only).
Average weight decreased by 7.6% from baseline.
Fasting insulin levels decreased by 30.6%.
Triglyceride levels decreased by 18.4%, and HDL cholesterol increased by 17.4%
High-sensitivity C-reactive protein (hs-CRP) decreased by 43.6%.
The use of diabetes medications, including insulin, dropped significantly, with a 50% reduction in insulin use.
Keto study
As a 3 year Virta patient I can vouch for the results. I've mentioned my transformation here previously and it's quite amazing. down 80lbs, a1c from 12.4 to 5.5. Stop eating processed food, no sugar, no carbs and lift weights at least 3 days a week. The only medication I've ever taken was metformin.
Here's the highlights:
20% of participants achieved diabetes remission according to international consensus criteria (HbA1c < 6.5% for at least three months without medication).
32.5% of participants reached diabetes reversal (HbA1c < 6.5% without medication or with metformin only).
Average weight decreased by 7.6% from baseline.
Fasting insulin levels decreased by 30.6%.
Triglyceride levels decreased by 18.4%, and HDL cholesterol increased by 17.4%
High-sensitivity C-reactive protein (hs-CRP) decreased by 43.6%.
The use of diabetes medications, including insulin, dropped significantly, with a 50% reduction in insulin use.
5
Posted on 1/28/25 at 9:39 am to hob
Keto cab definitely help with T2D. I think the biggest trigger in improving the lab numbers is really the weight loss in general.
When I was first diagnosed with T2D, my A1C was 8.6 and I weighed about 260lbs (5'11") needless to say I was fattt. I didn't workout or try to eat healthy at all. I toked it up every night and binged at night. I didn't do keto, but I started watching my calorie intake and focused on protein. I started moving more, and quit the weed. The weight started falling off consistently. After 6 months my A1C was down to 6.2 after losing 30lbs. After getting more structure by meal planning and actually working out over the next 4 months, I dropped another 30lbs to get to 200lbs. My A1C was 5.4.
I have hovered around 200lbs since then and my A1C has remained consistent. I got lazy with things due to an unexpected and stressful housing move, so I was eating sweets again like a dumbass. My A1C has remained in 5.5 range. I believe that I have "cured" my T2D at this point. Granted that's only if I keep myself from ballooning up.
I have started lifting now so I plan on getting below 200lbs by summer.
When I was first diagnosed with T2D, my A1C was 8.6 and I weighed about 260lbs (5'11") needless to say I was fattt. I didn't workout or try to eat healthy at all. I toked it up every night and binged at night. I didn't do keto, but I started watching my calorie intake and focused on protein. I started moving more, and quit the weed. The weight started falling off consistently. After 6 months my A1C was down to 6.2 after losing 30lbs. After getting more structure by meal planning and actually working out over the next 4 months, I dropped another 30lbs to get to 200lbs. My A1C was 5.4.
I have hovered around 200lbs since then and my A1C has remained consistent. I got lazy with things due to an unexpected and stressful housing move, so I was eating sweets again like a dumbass. My A1C has remained in 5.5 range. I believe that I have "cured" my T2D at this point. Granted that's only if I keep myself from ballooning up.
I have started lifting now so I plan on getting below 200lbs by summer.
Posted on 1/28/25 at 10:31 am to hob
I give them credit for performing and publishing a five year prospective study, they didn’t have to do that. And I agree that it does show that lifestyle changes can be transformative. However, it also shows what we’ve known for a long time, that diets for most people are very hard to stick to.
All of the success rates in this study use a denominator of 122 when they really should use 262, which is the number of people who started the ketogenic diet in the study at its beginning. Then, they only approached 192 to continue the study after 2 years (selection bias). Then only 122 actually completed the study (more bias). That 34% success rate suddenly becomes 15%. And these people were likely getting a lot of help from the company to get there that would be hard to replicate in a population, so really world success rates would be less
All of the success rates in this study use a denominator of 122 when they really should use 262, which is the number of people who started the ketogenic diet in the study at its beginning. Then, they only approached 192 to continue the study after 2 years (selection bias). Then only 122 actually completed the study (more bias). That 34% success rate suddenly becomes 15%. And these people were likely getting a lot of help from the company to get there that would be hard to replicate in a population, so really world success rates would be less
This post was edited on 1/28/25 at 5:02 pm
Posted on 1/28/25 at 10:33 am to NewOrleansBlend
quote:
However, it also shows what we’ve known for a long time, that diets for most people are very hard to stick to.
frick it then, just drug em up
Posted on 1/28/25 at 12:24 pm to hob
Not to rail on OP or anything, but why are researchers amazed that keto leads to remission of type 2?? Its been known for ages that weight loss leads to remission of type 2, except for some rare forms of type 2 id assume. Literally the mechanism of type 2 is cells getting so big that it starts wreaking havoc on cell receptors for insulin. Keto= weight loss Weight loss= type 2 remission
Cutting the sugar could definitely maybe help mitigate the damage of excessive blood sugar and the havoc that can wreak
Cutting the sugar could definitely maybe help mitigate the damage of excessive blood sugar and the havoc that can wreak
This post was edited on 2/1/25 at 8:00 am
Posted on 1/28/25 at 12:27 pm to hob
Any weight loss in general leads to improving glycemic status.
Posted on 1/29/25 at 12:11 pm to scottydoesntknow
quote:
Cutting the sugar could definitely maybe help mitigate the damage of excessive
Cutting sugar will definitely improve metabolic health
I’m type 2 for 9 yrs my last blood work was A1c 6.3. Down from 8.2 I requested a homa test my dr ask me why. My numbers on the way to remission been doing this since October
I would suggest anyone with diabetis to wear a Cgm
Posted on 1/29/25 at 3:50 pm to hob
Some of these natural responses to eliminating sugar and limiting carbs should tell you a lot.
Low carb also can help people with seizures. Knew a guy who lost a ton on Atkins and was epileptic. Went years without a seizure until he got off Atkins. There are some papers on treating epilepsy with it, I believe.
Low carb also can help people with seizures. Knew a guy who lost a ton on Atkins and was epileptic. Went years without a seizure until he got off Atkins. There are some papers on treating epilepsy with it, I believe.
Posted on 1/31/25 at 5:16 am to Mingo Was His NameO
quote:
frick it then, just drug em up
Sadly that is such an entrenched mindset and why RFK is so “radical”. I get what you are saying. This fight will be harder than the cigarettes campaign.
I wonder if they took into account (because I didn’t read it) how full subjects felt while eating ketogenic. I’d be surprised if they took that into consideration as major publications rarely do.
Posted on 1/31/25 at 11:17 am to NewOrleansBlend
quote:
that diets for most people are very hard to stick to.
But easy for them to stick to a bad diet.
If I changed my diet to drinking 10 dr peppers a day, I will find that personally hard to stick to.
Guess what I don't find hard to stick to? water and black coffee.
This post was edited on 1/31/25 at 11:19 am
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