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Posted on 9/22/25 at 9:55 pm to SallysHuman
You know just about every damn pregnant women took Tylenol at some point
Posted on 9/22/25 at 9:56 pm to ChatGPT of LA
quote:
You know just about every damn pregnant women took Tylenol at some point
Yes.
That's kind of the issue being pointed out.
Despite what Trump said- his team is advocating for a more judicious usage of tylenol. Not an absolute prohibition.
Posted on 9/22/25 at 10:44 pm to SallysHuman
Cubbies is avoiding this thread like a job interview.
Posted on 9/22/25 at 10:47 pm to Gusoline
quote:
Cubbies is avoiding this thread like a job interview.
I honestly hope she'll come back tomorrow and at least respond with something.
I don't need her to think tylenol is harmful... I just crave that she admits the industry and government aren't always forthcoming and that perhaps tylenol might NOT be 100% safe in pregnancy.
Posted on 9/22/25 at 10:50 pm to honeybadger07
4chubbies damned sure knows one of the side effects is NOT loss of appetite.
Posted on 9/22/25 at 10:55 pm to SallysHuman
quote:
Bump for 4cubbies
The only bump she’ll ever get
Posted on 9/22/25 at 11:54 pm to SallysHuman
At best, this is inconclusive. At worst, the link is just a convenient answer for a poorly posed question. And of course, these link should beg the question of the exact mechanism at play, in stark contrast to the association between neural tube defects and folate deficiency. The end result is going to be something even more stupid, where Tylenol will be withheld, perhaps leading to more cases of NSAID use during pregnancy.
Posted on 9/23/25 at 3:01 am to Trevaylin
Under Reagan’s Admin, he signed a deal that set up a “Separate Pharma Court” that houses the big cases and the Federal Reserve can bail them out. Aka Taxpayers.
Even Reagan has some fingerprints on today’s frickery that’s been going strong for 40+ years with immunity.
Even Reagan has some fingerprints on today’s frickery that’s been going strong for 40+ years with immunity.
Posted on 9/23/25 at 5:50 am to Dale Murphy
quote:
I’m a doctor. I don’t recommend the covid vaccine. I don’t throw meds at patients for mildly elevated glucose, blood pressure, or cholesterol. I voted for Trump three times.
But this is silly.
Is it the association proposed by the studies, Trump's heavy overselling it or both that you find silly?
Posted on 9/23/25 at 6:31 am to SallysHuman
quote:
The link includes links within the text.
Which link within this link did you find most compelling in forming your opinion that Tylenol causes autism?
I’m clicking on the links within the link you posted and I can’t find anything other than abstracts linking acetaminophen use to ADHD. This seems manipulative and intentionally vague.
I have not combed through everything though.
This post was edited on 9/23/25 at 6:36 am
Posted on 9/23/25 at 6:37 am to 4cubbies
quote:
I’m clicking on the links within the link you posted and I can’t find anything other than abstracts
If you get to the abstract- in the upper right hand corner of the page you will find "buttons" to view the full text.
Posted on 9/23/25 at 6:39 am to 4cubbies
quote:
can’t find anything other than abstracts linking acetaminophen use to ADHD.
The Nurse's study talks about ADHD, the Boston Birth Cohort talks about ADHD, ASD and other DDs.
Posted on 9/23/25 at 6:45 am to SallysHuman
These studies did not control for confounding factors nor did they have sibling controls. A critical component of research is for the researcher or others to try and disprove findings if one cannot disprove the findings than the research is better accepted. This was not the case here. .
When studies were done that account for that and use sibling controls, the association disappears.
When studies were done that account for that and use sibling controls, the association disappears.
This post was edited on 9/23/25 at 6:51 am
Posted on 9/23/25 at 6:50 am to LSUTANGERINE
quote:
These studies did not control for confounding factors nor did they have sibling controls. When studies are done that account for that and use sibling controls, the association disappears.
So some studies say one thing, others say another. Is that not a good reason to design and run a better study and advocate for limited usage of tylenol during pregnancy?
Nobody is banning tylenol- finding out what's going on and using it cautiously in the mean time is a very logical, measured approach.
Posted on 9/23/25 at 6:54 am to SallysHuman
quote:
in this cohort study of 996 mother-infant dyads from the Boston Birth Cohort, cord plasma biomarkers of fetal exposure to acetaminophen were associated with significantly increased risk of childhood attention-deficit/hyperactivity disorder and autism spectrum disorder.
Because all the subjects studied were at one specific hospital, the findings may not be generalizable. Acetaminophen also has a short half life. Exposure was measured only once (at birth). Since acetaminophen has a short half-life, the measurement likely reflects fairly recent exposure (peripartum), not necessarily throughout pregnancy.
These limitations are significant.
Considering the nearly ubiquitous use of Tylenol at some point during pregnancy, common sense tells me that the prevalence of autism would be much, much higher if this link was conclusive.
Posted on 9/23/25 at 6:57 am to SallysHuman
quote:
So some studies say one thing, others say another. Is that not a good reason to design and run a better study and advocate for limited usage of tylenol during pregnancy?
The research in the OP was severely lacking. The follow up research controlled for confounding factors and had sibling controls. Scientifically, those are much better studies.
Of course, I am all for dynamic rather than static, research. The example I gave is the initial research lead better research and it did not find the association.
The problem I have with yesterday is that the administration (at least Trump for sure.)was touting that Tylenol causes autism. That is patently false. Research does not support that. Trump should have never been in front of the microphone. He could not even pronounce acetaminophen.
This post was edited on 9/23/25 at 6:59 am
Posted on 9/23/25 at 6:58 am to 4cubbies
quote:
Considering the nearly ubiquitous use of Tylenol at some point during pregnancy, common sense tells me that the prevalence of autism would be much, much higher if this link was conclusive.
It IS much higher prevalence... ???
Posted on 9/23/25 at 7:02 am to LSUTANGERINE
quote:
The problem I have with yesterday is that the administration (at least Trump for sure.)was touting that Tylenol causes autism.
I agree that Trump's approach was heavy handed and probably not helpful.
About the sibling studies... do you have a quick link you can give me? I honestly haven't even seen an abstract so I can't comment on it yet.
Posted on 9/23/25 at 7:09 am to SallysHuman
Driving now. This can get you started.
JAMA network study (2024): A large-scale Swedish study published in JAMA analyzed data from over 2.4 million children, including matched full-sibling pairs.
Population analysis: An initial analysis without sibling controls found a small, statistically insignificant increase in the risk of autism and ADHD associated with prenatal acetaminophen exposure.
Sibling analysis: However, when researchers compared siblings born to the same mother—one exposed to acetaminophen in utero and the other not—the link to autism disappeared.
Conclusion: This suggests that any observed association was likely due to familial confounding, such as shared genetics or environmental factors, rather than the drug itself.
Replication by Japanese study: Another large, high-quality sibling-comparison study from Japan published in 2024 similarly found no link between prenatal acetaminophen use and autism.
Reason for controlling for siblings: Sibling comparison studies are valuable because full siblings share a significant portion of their genetic background and are exposed to many of the same familial and environmental factors. This design is better able to isolate the effect of a specific variable, like a medication, from other, unmeasured influences.
JAMA network study (2024): A large-scale Swedish study published in JAMA analyzed data from over 2.4 million children, including matched full-sibling pairs.
Population analysis: An initial analysis without sibling controls found a small, statistically insignificant increase in the risk of autism and ADHD associated with prenatal acetaminophen exposure.
Sibling analysis: However, when researchers compared siblings born to the same mother—one exposed to acetaminophen in utero and the other not—the link to autism disappeared.
Conclusion: This suggests that any observed association was likely due to familial confounding, such as shared genetics or environmental factors, rather than the drug itself.
Replication by Japanese study: Another large, high-quality sibling-comparison study from Japan published in 2024 similarly found no link between prenatal acetaminophen use and autism.
Reason for controlling for siblings: Sibling comparison studies are valuable because full siblings share a significant portion of their genetic background and are exposed to many of the same familial and environmental factors. This design is better able to isolate the effect of a specific variable, like a medication, from other, unmeasured influences.
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