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re: Moderna says FDA refusing to review application for its first mRNA-based flu shot

Posted on 2/11/26 at 4:05 pm to
Posted by Ailsa
Member since May 2020
8196 posts
Posted on 2/11/26 at 4:05 pm to
Posted by NC_Tigah
Make Orwell Fiction Again
Member since Sep 2003
138638 posts
Posted on 2/11/26 at 4:07 pm to
quote:

According to google AI the subclad K is a highly mutated version influenza A (H3N2) that first appeared in Australia in July of 2025. It mutated from the H3N2 strain that circulated next year.
Right. The point being, we guessed wrong.

Unless you have information we had a 3-6 month lead-time warning subcladeK was a player, I'm not sure of the relevance. Again, despite your contention that without guardrails, an mRNA vax could be ready in 3 months, IMO that is neither realistic nor safe.

quote:

According to google AI
You'll have to excuse me if I'm not yet there with your level of AI trust.
Posted by NC_Tigah
Make Orwell Fiction Again
Member since Sep 2003
138638 posts
Posted on 2/11/26 at 4:12 pm to
quote:

Well you are wrong doc.
Maybe so?

Look one post up from yours.

Posted by WeeWee
Member since Aug 2012
45530 posts
Posted on 2/11/26 at 4:13 pm to
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A single case. That is all you got? One case is not enough to even begin to think about forming a correlation yet alone causality.
Posted by WeeWee
Member since Aug 2012
45530 posts
Posted on 2/11/26 at 4:18 pm to
quote:

Well you are wrong doc.
Maybe so?

Look one post up from yours.


I linked a study that was published in the NEJM which shows mRNA vaccines being statistically superior to traditional vaccines. You say that traditional vaccines are more effective than mRNA vaccines but yet link no evidence to support your claim. Back up your claim with evidence or eat your humble pie.

quote:

Turns out this is exactly the type of trial design the FDA flagged in refusal-to-file letters for the mRNA flu vax. The FDA indicated licensed standard-dose vaccine as the comparator, as in this study, don't meet expectations for the “best-available standard of care”, particularly in older adults.


This was Pfzer's study and Pfzer has not been turned down by the FDA yet so try again Doc.
Posted by Ailsa
Member since May 2020
8196 posts
Posted on 2/11/26 at 4:22 pm to
quote:

quote:
FDA refusing to review application for its first mRNA-based flu shot


I wonder why!

............................

They might be held responsible?

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Have you seen the VAERs reports on the Mrna covid jab authorized only because it was declared an "emergency"?


Posted by Ailsa
Member since May 2020
8196 posts
Posted on 2/11/26 at 4:24 pm to
Posted by NC_Tigah
Make Orwell Fiction Again
Member since Sep 2003
138638 posts
Posted on 2/11/26 at 4:27 pm to
quote:

This was Pfzer's study and Pfzer has not been turned down by the FDA yet so try again Doc.
Have they been accepted?
Posted by WeeWee
Member since Aug 2012
45530 posts
Posted on 2/11/26 at 4:31 pm to
quote:

This was Pfzer's study and Pfzer has not been turned down by the FDA yet so try again Doc.Have they been accepted?


Don’t know. Tried to search for that information but every search is drown out by stories about Moderna and frankly I ain’t got the time nor desire to dig any deeper into the subject.


Still waiting on you to put up evidence to back your claim about traditional vaccines being superior up.
Posted by Ailsa
Member since May 2020
8196 posts
Posted on 2/11/26 at 4:32 pm to
quote:

This was Pfzer's study and Pfzer has not been turned down by the FDA yet so try again Doc.


Pfizer pays 2.8 million application fee to the FDA to get their vaccines approved.




Did you know that 75% of FDA funding comes from pharmaceutical companies?
Posted by the808bass
The Lou
Member since Oct 2012
128741 posts
Posted on 2/11/26 at 4:34 pm to
quote:

The data showed it was more effective than traditional shots.


How much you want to bet their data isn’t replicable?
Posted by Jauquismos
Member since Jul 2023
632 posts
Posted on 2/11/26 at 4:38 pm to
This is terrible news for the clot shot lovers
Posted by FutureMikeVIII
Houston
Member since Sep 2011
1755 posts
Posted on 2/11/26 at 4:40 pm to
quote:

Pfizer pays 2.8 million application fee to the FDA to get their vaccines approved.


So, this should be borne by the taxpayer?

Seems like the company submitting the application should pay the application fees to me.
Posted by WeeWee
Member since Aug 2012
45530 posts
Posted on 2/11/26 at 4:42 pm to
quote:

Unless you have information we had a 3-6 month lead-time warning subcladeK was a player,


There was a warning.

quote:

In tropical areas, there has been sustained influenza activity from June through November. Influenza A(H1N1)pdm09 viruses predominated through July. Since then, the proportion of influenza A(H3N2) viruses among reported detections has increased and has become predominant since the end of September (Fig. 3).


quote:

Subclade K viruses were particularly evident from August 2025 in Australia and New Zealand and have now been detected in more than 34 countries over the last 6 months.
WHO

It was noted to be increasing in multiple parts of the world in August and September. Which should have set off alarm bells that oh shite the flu shot isn’t going to work.

quote:

an mRNA vax could be ready in 3 months, IMO that is neither realistic nor safe.


An mRNA vaccine absolutely could be ready in 3 month if one was already being produced for older H3N2 strains. Safety is something that can only be determined through additional research which is what the pureblood good retards are trying to stop.
Posted by NC_Tigah
Make Orwell Fiction Again
Member since Sep 2003
138638 posts
Posted on 2/11/26 at 4:42 pm to
quote:

Still waiting on you to put up evidence to back your claim
I did. It is a similar premise to the Moderna rejection. We'll see.

In a day and age where funding drives studies (and results), I would like to see you asking more questions of the study you're citing though.

E.g., How many kilobases is the Pfizer translated segment?

Posted by WeeWee
Member since Aug 2012
45530 posts
Posted on 2/11/26 at 4:44 pm to
quote:

This is terrible news for the clot shot lovers


Sorry to burst your bubble but the clot shot is the J&J vector vaccine not an mRNA vaccine.
Posted by Froman
Baton Rouge
Member since Jun 2007
38902 posts
Posted on 2/11/26 at 4:45 pm to
Yay! Let’s go back to medieval times! Brung the plague back next.
Posted by NC_Tigah
Make Orwell Fiction Again
Member since Sep 2003
138638 posts
Posted on 2/11/26 at 4:55 pm to
quote:

There was a warning.
Again you're addressing a scenario where 6 months to produce a trad egg-based vax at scale is possible. Yet it was not done. That should be more your focus I'd imagine.
Posted by SallysHuman
Lady Palmetto Bug
Member since Jan 2025
21455 posts
Posted on 2/11/26 at 4:56 pm to
quote:

Brung the plague back next.


Who wants to tell him?
Posted by tigersmanager
Member since Jun 2010
11038 posts
Posted on 2/11/26 at 4:57 pm to
so overly dramatic weak
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