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LA County - 4% test positive for Antibody

Posted on 4/20/20 at 4:10 pm
Posted by hehateme2285
Katy, TX
Member since Dec 2007
5293 posts
Posted on 4/20/20 at 4:10 pm
LINK

Yet another antibody test that is tracking along with the other studies. This thing is completely widespread already.

quote:

from a collaborative scientific study that suggests infections from the new coronavirus are far more widespread - and the fatality rate much lower - in L.A. County than previously thought.


quote:

Based on results of the first round of testing, the research team estimates that approximately 4.1% of the county's adult population has antibody to the virus. Adjusting this estimate for statistical margin of error implies about 2.8% to 5.6% of the county's adult population has antibody to the virus- which translates to approximately 221,000 to 442,000 adults in the county who have had the infection. That estimate is 28 to 55 times higher than the 7,994 confirmed cases of COVID-19 reported to the county by the time of the study in early April. The number of COVID-related deaths in the county has now surpassed 600.
Posted by Powerman
Member since Jan 2004
170790 posts
Posted on 4/20/20 at 4:12 pm to
Pretty consistent with the Santa Clara numbers also
Posted by HailHailtoMichigan!
Mission Viejo, CA
Member since Mar 2012
73266 posts
Posted on 4/20/20 at 4:13 pm to
The usual wet rags will come into this thread and claim



MUH SELECTION BIASSSSSSSSSS
Posted by buckeye_vol
Member since Jul 2014
35373 posts
Posted on 4/20/20 at 4:13 pm to
quote:

Yet another antibody test that is tracking along with the other studies. This thing is completely widespread already.
Using the same unapproved Chinese test as the Stanford study, which has a false positive rate of at least 1.35%, but that assumes we’re trusting the Chinese manufacturer’s data.
Posted by Jyrdis
TD Premium Member Level III
Member since Aug 2015
13434 posts
Posted on 4/20/20 at 4:16 pm to
quote:

Participants were recruited via a proprietary database that is representative of the county population. The database is maintained by LRW Group, a market research firm.


This sounds like it should remove the selection bias.
Posted by moneyg
Member since Jun 2006
62197 posts
Posted on 4/20/20 at 4:16 pm to
quote:

Based on results of the first round of testing, the research team estimates that approximately 4.1% of the county's adult population has antibody to the virus


That's significantly lower than the other studies. At 4.1% we have a long way to go.
Posted by Jrv2damac
KS (mountain time)
Member since Mar 2004
72408 posts
Posted on 4/20/20 at 4:17 pm to
Where are the ventilators
Posted by TOKEN
Member since Feb 2014
11990 posts
Posted on 4/20/20 at 4:17 pm to
Very encouraging news.

It’s important to keep the stay at home orders in place a little longer but certainly good news.
Posted by buckeye_vol
Member since Jul 2014
35373 posts
Posted on 4/20/20 at 4:19 pm to
quote:

This sounds like it should remove the selection bias.
I think this study design seems much better than the Stanford one, but I still think we’re overestimating rates due to a higher false positive rate than is being estimated.

But I could see this one being off by far less than the Stanford one, which was pretty much worthless.
This post was edited on 4/20/20 at 4:20 pm
Posted by Jyrdis
TD Premium Member Level III
Member since Aug 2015
13434 posts
Posted on 4/20/20 at 4:23 pm to
I think you’re the only person I’ve seen to talk about this. I don’t necessarily agree with it, but I haven’t seen any of the twitter nerds complain about it (the people from Harvard, etc.). They all complained about study design.
Posted by buckeye_vol
Member since Jul 2014
35373 posts
Posted on 4/20/20 at 4:26 pm to
quote:

I think you’re the only person I’ve seen to talk about this. I don’t necessarily agree with it, but I haven’t seen any of the twitter nerds complain about it (the people from Harvard, etc.). They all complained about study design.
Andrew Gelman (well-known statistician) went into detail about a number of the statistical issues (from the Stanford Study), some I hadn’t even mentioned.

Concerns with that Stanford study of coronavirus prevalence
quote:

I think the authors of the above-linked paper owe us all an apology. We wasted time and effort discussing this paper whose main selling point was some numbers that were essentially the product of a statistical error.
Posted by honeybadger07
The Woodlands
Member since Jul 2015
4005 posts
Posted on 4/20/20 at 4:27 pm to
quote:

sing the same unapproved Chinese test as the Stanford study, which has a false positive rate of at least 1.35%, but that assumes we’re trusting the Chinese manufacturer’s data.


But we were so late on developing a test compared to everyone else i thought? now your saying those test from other countries we are using are not accurate enough??
Posted by Icansee4miles
Trolling the Tickfaw
Member since Jan 2007
31908 posts
Posted on 4/20/20 at 4:27 pm to
Not all of us are on Government assistance you stupid troll. Some of us have J O B S
Posted by WildManGoose
Member since Nov 2005
4600 posts
Posted on 4/20/20 at 4:29 pm to
quote:

false positive rate of at least 1.35%


quote:

which has a false positive rate of at least 1.35%
Source? I can't find anything.

Posted by uppermidwestbama
Member since Nov 2014
2097 posts
Posted on 4/20/20 at 4:29 pm to
Yep, it's been here for months already. In 5 years we will all be able to laugh at the stupidity over this virus and make fun of all involved. And yes I'm still voting for Trump in Nov.
Posted by Errerrerrwere
Member since Aug 2015
43853 posts
Posted on 4/20/20 at 4:31 pm to
quote:

I think this study design seems much better than the Stanford one,


Oh thank God!

Remembering how right you were and how much you argued Trump’s involvement with Russia during the 2016 election, means I can sleep tonight!

Thanks, a-hole! Your opinion means so much to me.
Posted by buckeye_vol
Member since Jul 2014
35373 posts
Posted on 4/20/20 at 4:33 pm to
quote:

Remembering how right you were and how much you argued Trump’s involvement with Russia during the 2016 election, means I can sleep tonight!
I don’t understand why you insist on lying about this for over 2 years.
Posted by Errerrerrwere
Member since Aug 2015
43853 posts
Posted on 4/20/20 at 4:36 pm to
quote:

I don’t understand why you insist on lying about this for over 2 years.


Just like Hineybadger said above. You flip- flopping mother fricker!

You are a professor at a two-bit junior college who drinks too much.

You will argue for the sake of arguing, while subtly inputting your stupid world view into any conversation.

The fact is; your opinion on ANYTHING isn’t worth shite. Carry on...
Posted by Jyrdis
TD Premium Member Level III
Member since Aug 2015
13434 posts
Posted on 4/20/20 at 5:00 pm to
That was an interesting read, and helps clear your position (in my head) a bit better. I have some skepticism about some points the author made such as:

quote:

If the specificity is 90%, we’re sunk. With a 90% specificity, you’d expect to see 333 positive tests out of 3330, even if nobody had the antibodies at all. Indeed, they only saw 50 positives, that is, 1.5%, so we can be pretty sure that the specificity is at least 98.5%.


as specificity and sensitivity are inversely related, so the results may be true, but it’s an assumption you have to take as given.

But this:

quote:

Why does their interval not include zero, then? I can’t be sure, but one possibility is that they did the sensitivity-specificity corrections on the poststratified estimate. But, if so, I don’t think that’s right. 50 positive tests is 50 positive tests, and if the specificity is really 98.5%, you could get that with no true cases.


is a more important point. As the authors of the Stanford study didn’t fully divulge all their methods, it can cast some doubts on the results. I do find it strange Ionnadis would do this.
Posted by MusclesofBrussels
Member since Dec 2015
4940 posts
Posted on 4/20/20 at 5:03 pm to
quote:

buckeye_vol




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