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re: Weight loss drug (Semaglutide) cut major adverse cardiovascular events by 20 percent

Posted on 8/8/23 at 9:22 pm to
Posted by LSUGUMBO
Shreveport, LA
Member since Sep 2005
9776 posts
Posted on 8/8/23 at 9:22 pm to

quote:

My understanding is that unless you change your eating habits, the user will just gain the weight back if they get off


So it’s just like every other diet/weight loss plan, then. The new habits have to stick.

Coming from the guy who’s done Atkins/low carb 2-3 times in the past 10 years, so he’s clearly an expert
Posted by tigerskin
Member since Nov 2004
46738 posts
Posted on 8/8/23 at 9:24 pm to
quote:

My understanding is that unless you change your eating habits, the user will just gain the weight back if they get off.

Drug companies will have a client for life which is usually the goal.


Well the cheapest route is just to not stuff your face, but we have difficulty with that
This post was edited on 8/8/23 at 9:27 pm
Posted by LRB1967
Tennessee
Member since Dec 2020
23173 posts
Posted on 8/8/23 at 9:24 pm to
Wouldn't any significant weight loss have the same effect regardless of whether Semaglutide was taken?
Posted by ThirdCoast13
Kingsville, Tx
Member since Apr 2020
15 posts
Posted on 8/8/23 at 9:25 pm to
So I've been on it 3 months. Not obese. Just not in game shape anymore. 5'10, 39 years old and weighed 198lbs when I started. Shift work and Terrible eating habits. Was $450 for about 5 months worth. No side effects I've seen. Reduced appetite, no more sweet cravings, etc. I'm down to about 175lbs. Done thru the shot and much improved eating habits.
Posted by SlimTigerSlap
Member since Apr 2022
4313 posts
Posted on 8/8/23 at 9:28 pm to
The problem with appetite suppressants is they don't work for people who eat for fun.
Posted by Team Vote
DFW
Member since Aug 2014
7955 posts
Posted on 8/8/23 at 9:30 pm to
quote:

For most people, those side effects will likely pale in comparison to the side effects of being obese.

It’s gonna be a no brainer. Like dealing with a stuffy nose from taking viagra
Posted by Basura Blanco
Member since Dec 2011
11747 posts
Posted on 8/8/23 at 9:36 pm to
quote:

It’s the American way. Don’t work on yourself just pop a pill.



I totally agree with you on the concept of people being too reliant on medication and will take it a step further and say its more of a reliance on better living thru chemistry, and the obesity epidemic itself is a result of that concept.

In 1990, 11.6% of American adults were obese. Today, its over 31%. There is no way in hell it rose that much that fast without some serious changes to the physical make up of the foods we eat. In effect, "easier" (processed)food thru chemistry has contributed to this epidemic as much as anything. And now, as sad as it seems, more chemistry might be the easiest answer to reversing the trend.
Posted by theunknownknight
Baton Rouge
Member since Sep 2005
60938 posts
Posted on 8/8/23 at 9:36 pm to
Probably cut the rate because these people were chub-o-lards in the first place
Posted by ItNeverRains
Offugeaux
Member since Oct 2007
28166 posts
Posted on 8/8/23 at 9:37 pm to
If I could cut to 155 safely I’d probably do it.
Posted by Ric Flair
Charlotte
Member since Oct 2005
13875 posts
Posted on 8/8/23 at 9:37 pm to
Is there any intrinsic value to the medicine itself, or is the risk reduction strictly due to weight loss?

I.e. someone with central obesity who weighs 220#’s. Weight loss to 200# with semaglutide down to 200# or weight loss with diet/exercise to 200#. Same risk reduction or better with the med?

Posted by lsupride87
Member since Dec 2007
111525 posts
Posted on 8/8/23 at 9:38 pm to
quote:

5'10, 39 years old and weighed 198lbs
quote:

Not obese
Posted by BobABooey
Parts Unknown
Member since Oct 2004
16133 posts
Posted on 8/8/23 at 9:39 pm to
I took an echocardiogram stress test at the doctor’s office today. That’s the one where they hook you up to a bunch of wires and you walk on a treadmill and they look at your heart like they look at a baby via sonogram. Sorry - didn’t mean to start out all technical and probably inaccurate.

Anyway, the obese woman giving the test said I’d walk until my heart rate hit 140 bpm. They’d keep speeding it up and increasing the incline until they got 140 and “the treadmill is undefeated” she assured me. Fast forward several minutes and the thing was going as fast and at the steepest incline that their lawyers would allow and I didn’t break 135bpm. She had me jump off and lay down fast because she said my heart rate would recover too fast.

Hey treadmill: STTDB!!!
Posted by Basura Blanco
Member since Dec 2011
11747 posts
Posted on 8/8/23 at 9:44 pm to
quote:

So it’s just like every other diet/weight loss plan, then. The new habits have to stick.


The way it was described to me is it eliminates the desire for sugar/carbs allowing a person to do an Atkins type diet very easily. This same person said they actually craved the feeling of not eating, which is mind blowing to a fatass like myself.
Posted by billjamin
Houston
Member since Jun 2019
18093 posts
Posted on 8/8/23 at 9:46 pm to
quote:

the thing was going as fast and at the steepest incline that their lawyers would allow

That sounds like a shitty doctor. Mine hooks me up and makes me run a mile on full out and I come back the following day for a VO2 test.
Posted by theunknownknight
Baton Rouge
Member since Sep 2005
60938 posts
Posted on 8/8/23 at 9:46 pm to
5’10 and 198 is technically obese
Posted by Ric Flair
Charlotte
Member since Oct 2005
13875 posts
Posted on 8/8/23 at 9:49 pm to
quote:

5'10, 39 years old and weighed 198lbs


Surprisingly, it’s the same BMI as someone 6’2” and 225#. Around 29. 5’10” and almost 200# visually looks a lot chubbier (discounting college football RB’s, crazy muscle mass).
Posted by AUstar
Member since Dec 2012
19624 posts
Posted on 8/8/23 at 9:53 pm to
I am all for it. The side effects cannot be worse than walking around just waiting for a heart attack because you fat as frick. And if people actually lose weight with it, then it sounds like a major breakthrough. Drug companies finna eat and investors gon be making bank.
Posted by BobABooey
Parts Unknown
Member since Oct 2004
16133 posts
Posted on 8/8/23 at 9:53 pm to
quote:

Mine hooks me up and makes me run a mile on full out

So the test is over in 5 minutes? Doesn’t sound very thorough.
Posted by Tarps99
Lafourche Parish
Member since Apr 2017
12729 posts
Posted on 8/8/23 at 9:56 pm to
quote:

The negative side effects will come out in a few years


They already know some of the side effects like vivid dreams, bowel control, loose stools, acid reflux, sulphur burns, etc.

Some depend on the dosage, one issue is that they start the dosage off small to prep your body for these changes and increase it the maximum dosage eventually. After a year, I am still not on the maximum dosage. But I have had some of those side effects still with the dosage I am on. I take a 7 mg Rybelius pill each day. It is the pill form of Ozempic/Semaglutide.
Posted by jcaz
Laffy
Member since Aug 2014
19304 posts
Posted on 8/8/23 at 9:59 pm to
Yeah but it just feeds the instant gratification fix we all seek.
I mean it’s not hard. Caloric deficit and just a few hours of exercise per week. People have no discipline
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