Trying to help a friend evaluate a job offer...

Here's some background info

His current job has very little to offer regarding growth and upward mobility, but there is very little stress, no one calls him for anything once he leaves the office, and he never has to bring work home. He also can take his vacation time whenever he wants to. He's able to telecommute at least once every other week. His salary is a little bit below market value for his field, but he has absolutely no stress at all. There's no bonus potential in his job either. He said that he's getting tired of having no growth in his career and doing the same ol' stuff everyday, but it's hard for him to leave where he is b/c it's so stress free.

He was recently offered a job at a chemical plant. He said they offered him $10k more than what he's making now, matched his current vacation time, and there's a bonus potential of 12% of his salary. He's worried b/c the requirements of the job will have him traveling between three different sites for shutdowns/turnarounds and he'll be on call 24x7. He also has concerns about the culture b/c a previous co-worker told him that the work environment wasn't all that great with management constantly calling you when you are supposed to be off.

He's been racking his brain over what to do the past few days. I've been trying to help him with the pros and cons of his dilemma. He has a deadline today to provide a response. I'm just wondering what some of y'all would do if you were confronted with a similar situation. As I see it, he has three choices he could make with each having its own consequences.

Option 1
Stay where he is and say nothing to his current employer since it's comfortable and wait until he finds what he's actually looking for that will make him happy.

Option 2
Go after the money knowing that it will potentially add more stress to his life. It probably will be very hard to deal with for a year or two, but once he got the hang of it he'll eventually be able to manage the responsibilities and in two years he'll look back and be glad he made the jump.

Option 3
Since he said he's in good standing with his current employer, he could possibly use the offer to leverage for more money. But he must be ready to leave if his current employer balks. This option is very risky.

These are the three things I told him and he asked me what I would do if I was in this situation. I told him that I really didn't know. Option 2 could really change his quality of life and has good and bad consequences. He could make a lot more money, but is it worth not seeing your family as much or having to get up and leave in the middle of your son's ball game because you got an emergency call at one of the sites your responsible for. Those are some really tough decisions. As you can see, I was no help with talking him through all this.