- My Forums
- Tiger Rant
- LSU Recruiting
- SEC Rant
- Saints Talk
- Pelicans Talk
- More Sports Board
- Fantasy Sports
- Golf Board
- Soccer Board
- O-T Lounge
- Tech Board
- Home/Garden Board
- Outdoor Board
- Health/Fitness Board
- Movie/TV Board
- Book Board
- Music Board
- Political Talk
- Money Talk
- Fark Board
- Gaming Board
- Travel Board
- Food/Drink Board
- Ticket Exchange
- TD Help Board
Customize My Forums- View All Forums
- Show Left Links
- Topic Sort Options
- Trending Topics
- Recent Topics
- Active Topics
Started By
Message
0
Posted on 8/23/21 at 2:44 pm to WDE24
quote:
WDE24
article after the massive shift in priority
It was for the treatment of Crigler-Najjar syndrome. But that's doesn't really matter.
It was all about the delivery mechanism.
Posted on 8/23/21 at 2:45 pm to Cosmo
quote:
30-40 years from now most cancers will be curable i suspect, even late stage
And I wonder if mRNA tech will be a big contributor to that...hmmmm
Posted on 8/23/21 at 2:47 pm to lsupride87
Thanks to the unvaxxed for doing a good job recovering and getting out!
Posted on 8/23/21 at 2:47 pm to Fun Bunch
quote:
And I wonder if mRNA tech will be a big contributor to that...hmmmm
Adults are talking.
It will be the mechanism, unless all out gene therapy is allowed.
Ironically, it will likely be advanced quite a few years by the largest set of human trials on history... The SARS "vaccine".
Posted on 8/23/21 at 2:49 pm to X123F45
quote:
Adults are talking.
That's rich.
Posted on 8/23/21 at 3:01 pm to X123F45
quote:I didn’t see anything in there about rats developing cancer or cancer as a result of nanoparticle lipids. I’m not disputing it, but just commenting that I haven’t seen it yet.
It was all about the delivery mechanism.
As it relates to the lipid nanoparticles, wasn’t it a breakthrough in that technology that made the vaccine successful where previous attempts at mRNA medicines had failed?
I’ve read briefly (not in depth) that Pfizer and moderna are both accused of ripping off the guy that developed delivery system for the mRNA vaccines.
Posted on 8/23/21 at 3:03 pm to X123F45
quote:
It was all about the delivery mechanism.
It is. And the LNPs are likely why the the mRNA vaccines were so effective against original COVID. Their inflammatory properties actually enhanced their efficacy.
quote:
Of note, their higher efficacy probably relies on activation of different inflammatory pathways exacerbated by direct cellular toxicity. The inflammatory properties of these LNPs’ should certainly be further exploited as an adjuvant platform in combination with proteins, subunit vaccines, or even in combination with existing attenuated vaccines (Bernasconi et al., 2021; Debin et al., 2002; Martins et al., 2007; Shirai et al., 2020; Swaminathan et al., 2016). LNPs, unlike other adjuvants, could thus serve a dual purpose, as both delivery vehicles for different cargos and as an adjuvant. However, it will be necessary to strike a balance between positive adjuvant and negative inflammatory properties as LNP-associated vaccines move forward. Since vaccine doses utilized in rodents are much higher than those used in humans(Nair and Jacob, 2016), detailed dose response studies will be required.
LINK
Posted on 8/23/21 at 3:03 pm to WDE24
quote:
How many days from the date La dropped below 1 on the estimated Rt before hospitalizations began decline?
Rt went from 1.01 to .96 between August 5th and 6th.
Which is also the day the 7 day average peaked in cases.
Rt is a leading indicator.
Posted on 8/23/21 at 3:05 pm to CatfishJohn
quote:
The recent spike has caused a big jump in vaccinations
What was the percentage jump in Louisiana to cause this rapid decline in hospitalizations?
Posted on 8/23/21 at 3:13 pm to RogerTheShrubber
Vaccinations over the last couple months havent done shite but will help months down the road
Delta is almost finished burning through LA
Thus this wave is nearing its denouement
Delta is almost finished burning through LA
Thus this wave is nearing its denouement
This post was edited on 8/23/21 at 3:14 pm
Posted on 8/23/21 at 3:14 pm to lsupride87
I’m sure this won’t make the news
Posted on 8/23/21 at 3:15 pm to RogerTheShrubber
quote:Recent vaccinations won’t really have much of an effect on the immediate decline in hospitalizations. They are more likely to reduce the population susceptible to hospitalization during the next wave.
What was the percentage jump in Louisiana to cause this rapid decline in hospitalizations?
Posted on 8/23/21 at 3:16 pm to waiting4saturday
They must have hind casted that some what. I remember it getting below around 8/12. I think they may have adjusted the estimated value when more actual data came in.
Posted on 8/23/21 at 3:48 pm to Topwater Trout
quote:
have we peaked?
We peaked 2 weeks ago
It takes time for hospitalizations to come down
Posted on 8/23/21 at 3:51 pm to Cosmo
quote:
Vaccinations over the last couple months havent done shite but will help months down the road Delta is almost finished burning through LA Thus this wave is nearing its denouement
Yep. This is ending because it’s running out of people to infect. Just like delta did in India without anyone vaccinated. Sharp spike, swift decline.
Posted on 8/23/21 at 3:56 pm to RogerTheShrubber
quote:
What was the percentage jump in Louisiana to cause this rapid decline in hospitalizations?
Reread my post
Posted on 8/23/21 at 3:59 pm to CatfishJohn
I'm really hoping that with some advancements in treatment this time around, we see more rapid recoveries and a more rapid wind down in hospitalized patients.
I'm hoping we are well under 1000 by the end of September (without a mass number of deaths).
I'm hoping we are well under 1000 by the end of September (without a mass number of deaths).
Posted on 8/23/21 at 4:04 pm to lsupride87
Posted on 8/23/21 at 4:04 pm to lsupride87
Page 7 of 12
Popular
Back to top
Follow TigerDroppings for LSU Football News