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Is a clinical trial better than direct medical care?
Posted on 5/19/20 at 5:37 pm
Posted on 5/19/20 at 5:37 pm
Seeing the MSM stories on guidance that says Trump shoukdnt be taking Hydroxychloroquine outside of a hospital or clinical trial.
Doesnt having 24/7 access to a doctor beat either of those?
Doesnt having 24/7 access to a doctor beat either of those?
8
Posted on 5/19/20 at 5:39 pm to Baldy
Haven't people travelling to tropical third world countries been taking it forever?
Posted on 5/19/20 at 5:42 pm to lsu13lsu
quote:
Haven't people travelling to tropical third world countries been taking it forever?
Lupus patients have been forever.
Granted their dose might be less. Or their prescribed dose at least.
Posted on 5/19/20 at 5:44 pm to Baldy
quote:
Doesnt having 24/7 access to a doctor beat either of those?
Depends on the doctor, I suppose
Posted on 5/19/20 at 5:44 pm to Baldy
Answer depends of if you are a Republican or stupid.
Posted on 5/19/20 at 5:45 pm to Baldy
Side rant. frick clinical trials and their archaic bullshite regulations. People with ALS have been used like mice in an experiment for the past 10 years with a treatment that has shown promise. 100% kill rate yet we bend over backwards for Covid. Double blind placebo trials can suck a dick.
Posted on 5/19/20 at 5:48 pm to Turftoe
quote:
Double blind placebo trials can suck a dick.
Screw science with your balls
Posted on 5/19/20 at 6:08 pm to Turftoe
quote:
with a treatment that has shown promise
What treatment is that?
Posted on 5/19/20 at 6:16 pm to JudgeHolden
quote:
What treatment is that?
Nurown from Braincell. Not only has it stalled the progression, but in some cases symptoms regressed.
Posted on 5/19/20 at 6:33 pm to JudgeHolden
quote:
What treatment is that?
I'm not sure. My dad died with ALS, and I know that occasionally new trials will come along that provide some hope. Unfortunately, none have have been all that successful.
ALS is a terrible, terrible disease. It can attack a person's body in so many different ways and kill quickly, or leave a person suffering in numerous ways. If ever there was a diseases worthy of every penny it gets, ALS is it. It is a heartbreaking disease.
Posted on 5/19/20 at 6:37 pm to LegendInMyMind
Had three first cousins die from that crap. Have a 4th fighting it, but has gone down hill fast. 
Posted on 5/19/20 at 8:32 pm to Turftoe
quote:
Nurown
25% SAEs. Safety is an issue.
Neuros have always told me that stem cells are a swing and a miss with ALS.
Posted on 5/19/20 at 8:33 pm to LegendInMyMind
quote:
It is a heartbreaking disease.
Sadly, I am all too aware.
Posted on 5/19/20 at 9:53 pm to Baldy
LINK Everything & every study re: hydroxy-chloroquine + z-pack, zinc, & other combos
These are quite technical papers & studies, definitely not bathroom reading. From the beginning the physicians & researchers have been consistent in stating that treatment needs to be started immediately at the onset of symptoms not once a patient is admitted into an ICU or put on a vent. That goes for Remdesivir as well, both treatment options have shown great promise, but neither is a wonder drug or cure, especially if a patient is critical. The HCQ lowers your immune system response so your body doesn’t go into overkill/Cytokine storm & the Z-pack is to kill any secondary infections aka pneumonia. Cannot speak for Remdesivir or how it works to temper the effects of the virus other than it is administered IV only and is quite expensive for a 5-day treatment(20-25K). Everything you put in your body can have adverse effects(read the back of an ibuprofen bottle) the major concern w/ HCQ is the development of a heart arrhythmia, but it’s been in use for so long they know that’s an average of 1 in 10,000. If you take HBP meds you know the drill, an EKG is standard during your 6 month or yearly and especially if your changing HBP meds. Interesting enough, it was just announced today that Washington University(STL) one of the best med schools in the country was starting a clinical study of 30,000 dr.’s, nurses, front line personnel and responders on a regimen of HCQ + Z-pack and other combos.
LINK Wash. U. HCQ study set to begin
These are quite technical papers & studies, definitely not bathroom reading. From the beginning the physicians & researchers have been consistent in stating that treatment needs to be started immediately at the onset of symptoms not once a patient is admitted into an ICU or put on a vent. That goes for Remdesivir as well, both treatment options have shown great promise, but neither is a wonder drug or cure, especially if a patient is critical. The HCQ lowers your immune system response so your body doesn’t go into overkill/Cytokine storm & the Z-pack is to kill any secondary infections aka pneumonia. Cannot speak for Remdesivir or how it works to temper the effects of the virus other than it is administered IV only and is quite expensive for a 5-day treatment(20-25K). Everything you put in your body can have adverse effects(read the back of an ibuprofen bottle) the major concern w/ HCQ is the development of a heart arrhythmia, but it’s been in use for so long they know that’s an average of 1 in 10,000. If you take HBP meds you know the drill, an EKG is standard during your 6 month or yearly and especially if your changing HBP meds. Interesting enough, it was just announced today that Washington University(STL) one of the best med schools in the country was starting a clinical study of 30,000 dr.’s, nurses, front line personnel and responders on a regimen of HCQ + Z-pack and other combos.
LINK Wash. U. HCQ study set to begin
Posted on 5/19/20 at 10:07 pm to Baldy
There’s absolutely no evidence that hydroxychloroquine has any prophylactic value as far as the virus is concerned, and of all the people that should be experimenting on themselves, basically doing their own anecdotal trial, the 73 year old POTUS is probably the last person on Earth that should be doing it.
Not to mention the clinical trial for use of the drug as a treatment was a complete failure. I personally think he’s doing it because he talked it up so much and it didn’t work, and now he’s reaching for anything to give himself some credibility as far as the drug’s effectiveness and trying to save face.
Also, the entire reason hydroxychloroquine was suggested as a treatment in the first place is because it allows zinc to enter cells, which it can’t do on its own, and zinc stops the spread of the virus in the cell. In short, taking hydroxychloroquine without taking zinc is basically taking it just to take it; without the zinc there is no benefit.
Not to mention the clinical trial for use of the drug as a treatment was a complete failure. I personally think he’s doing it because he talked it up so much and it didn’t work, and now he’s reaching for anything to give himself some credibility as far as the drug’s effectiveness and trying to save face.
Also, the entire reason hydroxychloroquine was suggested as a treatment in the first place is because it allows zinc to enter cells, which it can’t do on its own, and zinc stops the spread of the virus in the cell. In short, taking hydroxychloroquine without taking zinc is basically taking it just to take it; without the zinc there is no benefit.
This post was edited on 5/19/20 at 10:09 pm
Posted on 5/19/20 at 10:14 pm to Baldy
I live here in Maryland not far from some of the best medical minds in the nation and I truly want to volunteer to be a human guinea pig for them and help out but none of them even want me. Not NIH, Johns Hopkins, nor the FDA. I don’t fit their criteria as a patient.
As to the OP no matter what Trump does he will get blatant hatred and malice from the “news media” and democrats. He could give all his money to charity, give every undocumented immigrant american citizenship, and pardon every black person in prison and they would still troll and attack him for something.
As to the OP no matter what Trump does he will get blatant hatred and malice from the “news media” and democrats. He could give all his money to charity, give every undocumented immigrant american citizenship, and pardon every black person in prison and they would still troll and attack him for something.
Posted on 5/19/20 at 10:17 pm to Baldy
Doctors base their practice on the outcomes of clinical trials. Clinical trials are set up to see if there is a statistically significant difference between using one drug vs. either a placebo or another drug.
Posted on 5/19/20 at 10:57 pm to Jizzy08
quote:
Doctors base their practice on the outcomes of clinical trials. Clinical trials are set up to see if there is a statistically significant difference between using one drug vs. either a placebo or another
Then why am I seeing some Drs swear it works and others swear it doesn't? Politics?
Posted on 5/19/20 at 11:01 pm to Corkfather
For what it’s worth, there’s absolutely NO way that OMB or any other members of his cabinet/inner circle aren’t being administered something far more effective than a generic $.02 drug & a Z-pack. Hell we know for a fact that Moderna & a host of others are already well into phase II. Anti-body treatments show great promise as well, especially until a proven winner/winners of the great vaccine wars of 2020 emerge. What did Boris Johnson receive 6 weeks ago and why is that such a secret from the general public?
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