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re: Image of a virus taken by an electron microscope
Posted on 3/14/18 at 5:41 pm to weagle99
Posted on 3/14/18 at 5:41 pm to weagle99
That is probably (looks like) a T4 macrophage.
The geometric looking top is an elongated Icosahedron (30 sided structure) and it contains the viral genetic material.
If I am right (about it being a T4), that one replicates on E.coli bacteria - specific to that organism. In liquid, it floats around until the legs touch the cell wall of the E.coli bacterium. When the legs tough,they attach and the virus squats down until the base (where the legs attach to the column, which is made out of protein molecules, constructed in a spiral molecular configuration) touches the cell wall.
There are small enzyme containing spears there (sticking out of the base) that eat a hole in the E.coli cell wall. When the hole opens up, the spiral protein column contracts (like a spring and injects the DNA fro the head, down the hollow column and into the bacterium.
The DNA interferes with the bacterium's cellular functions and takes over the metabolic genetic replication process allowing the viral DNA to replicate. Pretty quickly, several hundred T4 phages are created within the E.coil and when that happens, the cell sort of explodes, releasing the viruses into the medium where they float around until the contact another E.coli and it starts over again.
You can seed a flask of E.coli in liquid medium with a few T4 phages and within a day or so, they will wipe out every one of billions and billions of bacterial cells in the Flask. There is no hope for them, once the first phage hits the first E.coli cell.
Thanks for letting me brain dump old virology lecture material on you guys.
I know you know this. Viruses are not living creatures, They do not take in food, they do not metabolize and they do not grow. All of these need to happen if we call something alive. They are only genetic replication (chemical)machines.
This post was edited on 3/14/18 at 5:44 pm
Posted on 3/14/18 at 5:48 pm to weagle99
It's not biological. I for one welcome our alien reprogramming devices.
Posted on 3/14/18 at 5:49 pm to weagle99
Looks like those Flood organism in the Halo games
Posted on 3/14/18 at 5:50 pm to cj35
CJ - did you do graduate research in virology?
My Thesis was titled: "A light and electron microscope study of akinite formation and germination in Anabaena flos aqua - A-37"
Anabaena is a Blue Breen Alga, commonly found in sewage ponds.
If your search engine is good enough you can find me.
My TEM work was done on this guy
Used a Hitachi SEM.
Very close to this one
My Thesis was titled: "A light and electron microscope study of akinite formation and germination in Anabaena flos aqua - A-37"
Anabaena is a Blue Breen Alga, commonly found in sewage ponds.
If your search engine is good enough you can find me.
My TEM work was done on this guy
Used a Hitachi SEM.
Very close to this one
This post was edited on 3/14/18 at 6:02 pm
Posted on 3/14/18 at 7:18 pm to MeridianDog
quote:
Viruses are not living creatures, They do not take in food, they do not metabolize and they do not grow. All of these need to happen if we call something alive.
That's a rather curt dismissal of an entity that is a fundamental player in the history of life. While it certainly occupies the unique position at the point of life and non-life, it is the ultimate parasite.
To me its ability to evolve in parallel with its prey places it firmly in the category of the living. While so-called higher life forms metabolize and grow, viruses don't need to because they can command other organisms to do that for them. As the attached article indicates, we ignore the sophistication of viruses at our peril.
Are Viruses Alive? - Scientific American
quote:
...a virus consists of nucleic acids (DNA or RNA) enclosed in a protein coat that may also shelter viral proteins involved in infection. By that description, a virus seems more like a chemistry set than an organism. But when a virus enters a cell (called a host after infection), it is far from inactive. It sheds its coat, bares its genes and induces the cell’s own replication machinery to reproduce the intruder’s DNA or RNA and manufacture more viral protein based on the instructions in the viral nucleic acid. The newly created viral bits assemble and, voilà, more virus arises, which also may infect other cells.
Posted on 3/14/18 at 7:28 pm to weagle99
Would be interesting to learn the evolution of viruses.
Posted on 3/14/18 at 9:08 pm to weagle99
So, the movie Osmosis Jones wasn't that far off?
Posted on 3/14/18 at 9:34 pm to weagle99
Looks like the Google AI built himself some more legs
Posted on 3/14/18 at 9:47 pm to Kentucker
Kentucker - I never said they weren't amazing in what they do, but historically, an organism must meet certain characteristics to be termed a "Living" entity. Viruses meet almost none of these requirements.
Not to say they are not incredibly engineered clusters of chemicals in order to do what they do.
They are chemical replication machines. Yes they are parasites, but viral, not living entities.

Not to say they are not incredibly engineered clusters of chemicals in order to do what they do.
They are chemical replication machines. Yes they are parasites, but viral, not living entities.

This post was edited on 3/14/18 at 9:49 pm
Posted on 3/14/18 at 9:48 pm to weagle99
I know it is enhanced but still amazing. Imagine if we could genetically manufacture a virus that attacked only cancerous cells but left all others intact. Like chemo but without healthy cell death. Would be fricking life changing.
Posted on 3/14/18 at 11:01 pm to jennBN
Or it could mutate and wipe out the human race.
Posted on 3/14/18 at 11:05 pm to weagle99
It’s amazing how they even look evil. Seriously, that looks like a mean motherfricker. Like a damn wasp.
Posted on 3/14/18 at 11:22 pm to JumpingTheShark
D. Villeneuve’s Enemy.


Posted on 3/14/18 at 11:25 pm to weagle99
This was old when I was in school (decade ago)
Posted on 3/14/18 at 11:49 pm to weagle99

Next time you have a bacterial infection raging in your rectum recognize that that size does matter.
Posted on 3/15/18 at 12:09 am to Lake Vegas Tiger
quote:
This was old when I was in school (decade ago)

We worked with them when I was in school 55 years ago. Somewhere in the Attic I actually have transmission electron micrographs of T2 viral particles - the wiser 1st cousin of the T4 guys. Mine aren't this good, because this one is a scanning electron micrograph that shows a lot more 3D detail then a TEM which looks more 1 dimensional.
Of course, they have been around for 1,000,000 + years so they have that going for them, too.

This post was edited on 3/15/18 at 12:23 am
Posted on 3/15/18 at 12:10 am to MeridianDog
So these things eat the E Coli? So this wicked looking thing is a good guy?
Posted on 3/15/18 at 12:13 am to biglego
They do no harm to mankind. They will attack the most virulent strains of E.coli.
Care to guess where you can find some of them? In your toilet water after you take a big dump. They are likely to be up inside of you right now.
Edited to add - They don't eat E.coli. They don't eat anything. They attack them, go inside of them and take over the E.coli while they are (biochemically) sucking them out to replicate.
Care to guess where you can find some of them? In your toilet water after you take a big dump. They are likely to be up inside of you right now.
Edited to add - They don't eat E.coli. They don't eat anything. They attack them, go inside of them and take over the E.coli while they are (biochemically) sucking them out to replicate.
This post was edited on 3/15/18 at 12:17 am
Posted on 3/15/18 at 12:17 am to MeridianDog
That’s pretty awesome and I’m suddenly inspired to take a dump.
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