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re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***

Posted on 3/4/20 at 12:22 pm to
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 3/4/20 at 12:22 pm to
The fricking CDC didn’t even find the first case. This group in Seattle had to develop their own test to find what they knew was there. Unbelievable.

STATnews

quote:

The spread of the virus has gone undetected in part because many infected people experience only mild infections that could be confused for a cold or the flu, and in part because of stumbles in the Centers for Disease Control and Prevention’s effort to develop test kits for state and local public health laboratories, which has meant very little testing has been done in the country until the past few days.

The case was actually found by the Seattle Flu Study. Bedford, a co-investigator, normally works on influenza but has been one of the key players trying to assess what is happening with the new virus by studying genetic sequences from around the world.

Frustrated by the lack of testing resulting from the problem with the CDC-developed kit, the Seattle Flu Study began using an in-house developed test to look for Covid-19 in samples from people who had flu-like symptoms but who had tested negative for flu. That work — permissible because it was research — uncovered the Snohomish County teenager.
This post was edited on 3/4/20 at 12:23 pm
Posted by BallsEleven
Member since Mar 2019
6163 posts
Posted on 3/4/20 at 12:26 pm to
Wow.

What does it take to replace top brass at the CDC?
Posted by Bullfrog
Running Through the Wet Grass
Member since Jul 2010
61220 posts
Posted on 3/4/20 at 12:28 pm to
Zombies, bra.
Posted by 50_Tiger
Arlington TX
Member since Jan 2016
43463 posts
Posted on 3/4/20 at 12:29 pm to
3.95%

Which is slightly higher than the WHO 3.71% figure.

Hmmmm....
Posted by Dominate308
South Florida
Member since Jan 2013
2895 posts
Posted on 3/4/20 at 12:30 pm to
WaWaWeeWa is the Federal Goverment. They never sleep and are here to steer and control the discussion. It is obviously more than one person. This site has been compromised.

Now watch the response.
Posted by Oates Mustache
Member since Oct 2011
26630 posts
Posted on 3/4/20 at 12:31 pm to
With so much arguing going on in this thread I think there's only one thing universally agreed upon. The CDC is filled with a bunch of incompetent buffoons.

This post was edited on 3/4/20 at 12:31 pm
Posted by Dominate308
South Florida
Member since Jan 2013
2895 posts
Posted on 3/4/20 at 12:36 pm to
This link has run its course. The government is censuring media now.
Posted by slackster
Houston
Member since Mar 2009
91838 posts
Posted on 3/4/20 at 12:36 pm to
quote:

This proves my point. It’s saying that 78% of pneumonia deaths are due to flu. It’s just wrong. There are countless other causes of pneumonia, flu is minuscule on that list.


No, no it's not. You don't understand the methodology or the numbers.

The numbers I posted were the death certificate causes of death. The CDC's model believes a portion of those pneumonia deaths are from the flu, but it also believes there are deaths attributable to other death certificate causes that are actually flu related as well. The Venn diagram of CDC flu deaths would include some of those P&I deaths, but it would mostly include complications resulting from the flu - typically the worsening of underlying conditions.

Think about this in a practical sense - the majority of deaths due to COVID-19 are people with underlying medical issues. The CDC believes the same thing happens with the flu. Either they all count for COVID-19 and influenza, or none of them count.
Posted by Bullfrog
Running Through the Wet Grass
Member since Jul 2010
61220 posts
Posted on 3/4/20 at 12:38 pm to
I’m just wondering which are part of the 2000 chineses working on social media spin control.

Sure the feds have their bots on maximum linguistic processing to direct their social media response team.
Posted by Bullfrog
Running Through the Wet Grass
Member since Jul 2010
61220 posts
Posted on 3/4/20 at 12:40 pm to
I can no longer tell which one of you is for higher or lower death rates from COVID19 infections and suspected infections.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 3/4/20 at 12:43 pm to
quote:

The numbers I posted were the death certificate causes of death.


A large group of causes of death combined into one.

I’m breaking down that number from the actual causes on the death certificate. Go to the link and look for yourself.

There are 8 different death certificates causes that encompass every flu death. Wether from flu directly or a complication of flu. They even have 4 different causes for a case where you think there was flu but no test was done. These are (virus not identified).

Here are the categories:

Flu (indentified virus) - 215
Flu with pneumonia (identified virus) - 95
Flu/ other respiratory manifestations (virus identified) - 112
Flu/ other manifestations (virus identified) - 8

Flu (virus not identified) - 634
Flu with pneumonia (virus not identified - 322
Flu/other respiratory manifestations (virus not identified) - 301
Flu/ other manifestation (virus not identified) - 11


So give me an example of a case of flu death that couldn’t be put in one of these categories.
This post was edited on 3/4/20 at 12:45 pm
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 3/4/20 at 12:52 pm to
quote:

I can no longer tell which one of you is for higher or lower death rates from COVID19 infections and suspected infections.


We both think they are lower than reported. How much, is almost impossible to predict with so many variables.
Posted by slackster
Houston
Member since Mar 2009
91838 posts
Posted on 3/4/20 at 1:03 pm to
quote:

The causes of bacterial pneumonia can be endless and have nothing to do with flu, but these are somehow included in the data.


Once again, no, no they are not.

quote:

For the 1990-1991 through 1998-1999 seasons, the greatest mean numbers of deaths were associated with influenza A(H3N2) viruses, followed by RSV, influenza B, and influenza A(H1N1). Influenza viruses and RSV, respectively, were associated with annual means (SD) of 8097 (3084) and 2707 (196) underlying pneumonia and influenza deaths, 36 155 (11 055) and 11 321 (668) underlying respiratory and circulatory deaths, and 51 203 (15 081) and 17 358 (1086) all-cause deaths.


quote:

However, numbers of deaths attributable to influenza are difficult to estimate directly because influenza infections typically are not confirmed virologically or specified on hospital discharge forms or death certificates. In addition, many influenza-associated deaths occur from secondary complications when influenza viruses are no longer detectable.4,5 Nonetheless, wintertime influenza epidemics have been shown to be associated with increased hospitalizations and mortality for many diagnoses, including congestive heart failure, chronic obstructive pulmonary disease, pneumonia, and bacterial superinfections



LINK

Feel free to start in the references and read article after article that explains why "influenza and pneumonia" deaths are actually a very small part of the CDC estimate. Your conclusion that all pneumonia deaths - or even most pneumonia deaths - are calculated as the flu is simply incorrect. This study pegs influenza for less than 10% of P&I deaths. However, P&I death reports are useful because they're available in near real-time, hence the CDC surveillance and epidemic threshold:



quote:

Any possible cause of mortality related to flu can be classified in one of those categories.


Sure, but it's not. That's the point, and study after study shows that to be true.


Posted by GeauxTigers2020
Member since Sep 2013
28667 posts
Posted on 3/4/20 at 1:21 pm to
quote:

Frustrated by the lack of testing resulting from the problem with the CDC-developed kit, the Seattle Flu Study began using an in-house developed test to look for Covid-19 in samples from people who had flu-like symptoms but who had tested negative for flu. That work — permissible because it was research — uncovered the Snohomish County teenager.


Feel so good about the CDC keeping me safe.
Posted by GeauxTigers2020
Member since Sep 2013
28667 posts
Posted on 3/4/20 at 1:30 pm to
Fabrizio Romano is a leading reporter on Italian soccer:

quote:

Official: new COVID decree measures here in Italy. All sports events - also Serie A - can only be done behind closed doors for 30 days. No more fans in the stadiums. The measures will be effective until April 3. ??????
This post was edited on 3/4/20 at 1:36 pm
Posted by NeonSunburst
Member since Oct 2010
2877 posts
Posted on 3/4/20 at 1:36 pm to
jackwoods4
Fabrizio Romano is a leading reporter on Italian soccer:

quote:

LINK ]

[quote]Official: new COVID decree measures here in Italy. All sports events - also Serie A - can only be done behind closed doors for 30 days. No more fans in the stadiums. The measures will be effective until April 3.
Posted by Volvagia
Fort Worth
Member since Mar 2006
53480 posts
Posted on 3/4/20 at 1:37 pm to
quote:

Frustrated by the lack of testing resulting from the problem with the CDC-developed kit, the Seattle Flu Study began using an in-house developed test to look for Covid-19 in samples from people who had flu-like symptoms but who had tested negative for flu. That work — permissible because it was research — uncovered the Snohomish County teenager.




As I said....politics not technical problem.

The sequence is public knowledge, there are even public domain tools to help you design it.

Vial of custom reagent is around 60 bucks.

Only real barrier to entry is the 20-70k thermal Cycler.
Posted by NeonSunburst
Member since Oct 2010
2877 posts
Posted on 3/4/20 at 1:48 pm to
Agreed. I submitted some samples (nonhuman and not related to this virus) for sequencing monday. They already have the primers and probes designed.
We have 2 real time machines and 3 thermocyclers in our lab. In the building, we probably have 3x that many. Just in this building. There are numerous labs in this small area with multiple RTqPCR and thermocyclers. I can't imagine why we could theoretically test over 200 samples per PCR run per day. Depending on how long of a pcr program it is, some are 1 hour and some are 6 hour runs, we might could squeeze out double that number.

My question is...
How can a small town lab have this capability but the CDC or whoever is running these tests, cant produce more than 6 per day? (6 was the number i heard yesterday)

Posted by slackster
Houston
Member since Mar 2009
91838 posts
Posted on 3/4/20 at 1:52 pm to
quote:

They take a step further and say “pneumonia” anywhere on the death certificate is included in their calculations. Even if the cause is specified. This is directly from the methods give by the CDC


Completely fabricated. Your thread on the Political Talk is full of half truths and poor understanding of the source material. Part of that smoking gun definition change you think you found in 1999-2000 data actually reduced P&I reported deaths by over 30% with ICD-10. Those reports flow down to the mortality tables you're referencing.

LINK

quote:

A change in the direct sequel rule (Rule 3) is responsible for the comparability ratio of 0.6982 for Influenza and pneumonia (113-list number 076). While Influenza (113-list number 077) is largely unaffected by the revision (comparability ratio of 1.0088), Pneumonia(113-list number 078) has a comparability ratio of 0.6957. When pneumonia is listed on the death certificate with another cause of death, and it is obviously a direct consequence of that other cause, then the other cause is selected as the underlying cause of death. In ICD–10, this rule is applied more broadly than in ICD–9 and specifies many more causes for which pneumonia is considered a direct consequence. Thus, deaths classified as pneumonia in ICD–9 are classified in ICD–10 to many other causes. The most prominent causes are Diseases of heart, Cerebrovascular diseases, Malignant neoplasms, Chronic lower respiratory diseases, Septicemia, Malnutrition, and Chronic liver disease and cirrhosis.


What the CDC changed in 1999-2000 was how they monitored real-time (weekly) reports of P&I deaths for their weekly epidemic surveillance. For example, in 2016, based on ICD-10 specific death codes, which attempt to classify a death to a primary cause, influenza deaths were 6,515 and pneumonia deaths were 49,157. However, the broad CDC monitoring of influenza or pneumonia being mentioned anywhere says influenza deaths were 8,135 and pneumonia deaths were 180,151. That CDC weekly monitoring is NOT their estimated death burden - it's simply their tool for monitoring whether or not an epidemic is occurring. The change in 1999-2000 by the CDC simply changed the baseline for monitoring epidemics, it was not a change in the methodology for estimated deaths.

Posted by boxcarbarney
Above all things, be a man
Member since Jul 2007
26722 posts
Posted on 3/4/20 at 2:02 pm to
quote:

20-70k thermal Cycler.


That's pricey on a Burger King salary.
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