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re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***

Posted on 5/19/20 at 4:31 pm to
Posted by Sasquatch Smash
Member since Nov 2007
25958 posts
Posted on 5/19/20 at 4:31 pm to
quote:

You said "proven", and the article says no such thing.


Go back and read as to what I said was proven, then come back and apologize because you can’t read.

quote:

If your aim is to fight against these policies, I do not recommend doing so by seeking out incomplete data that maximizes the upward uncertainty in covid deaths. We should try to minimize that uncertainty so as to avoid another "surprise" overreaction.


Why not? It’s a tool available to us. These policies were put into place using shitty models that made lots of assumptions, using worse data than this, which have been quite wrong throughout. This incomplete data is better than the incomplete data that got us into this mess.

This isn’t math or physics. This is biology. You’re never going to get perfect datasets.
Posted by Glock17
Member since Oct 2007
23181 posts
Posted on 5/19/20 at 4:42 pm to
BR general did a antibody test and found 4.5% positive

LINK
Posted by Korkstand
Member since Nov 2003
29128 posts
Posted on 5/19/20 at 5:11 pm to
quote:

Go back and read as to what I said was proven, then come back and apologize because you can’t read.
I've read it several times, and each time it has shown that you said "proven", as if to imply that the remaining "unproven" excess deaths should be attributed to policy rather than covid. You go on to say "thus far" and that "underdiagnosis is likely", which further confuses me on why you chose to use the word "proven" given that it doesn't appear once in the linked article. It just comes across as deceptive language.
quote:

Why not? It’s a tool available to us. These policies were put into place using shitty models that made lots of assumptions, using worse data than this, which have been quite wrong throughout. This incomplete data is better than the incomplete data that got us into this mess.
I can agree with all of that, but my concern is that pushing this idea that covid mortality rates are lower than reality will lead to another round of bad policy in the winter when deaths start happening more often than the new models based on an underestimated IFR predict. In other words, if we want to avoid another round of panic-induced policy, we need to see deaths in line with or less than what the models predict. Because if deaths start piling up faster than we expect, we will surely overreact again.

Posted by Sasquatch Smash
Member since Nov 2007
25958 posts
Posted on 5/19/20 at 5:25 pm to
quote:

I've read it several times, and each time it has shown that you said "proven", as if to imply that the remaining "unproven" excess deaths should be attributed to policy rather than covid. You go on to say "thus far" and that "underdiagnosis is likely", which further confuses me on why you chose to use the word "proven" given that it doesn't appear once in the linked article. It just comes across as deceptive language.


How is saying that 10,000 deaths, of the 30,000 excess deaths, have thus far been proven/confirmed/written on the death certificate as a CoviD death deceptive?

I’m not going to get into your second retort where you tout assumptions as fact and then try to prop up future models as some truth whenever the original models have missed reality be like 10-100x all over.

I’m done arguing with you about this. Enjoy the night shift of fighting your fights.
Posted by Korkstand
Member since Nov 2003
29128 posts
Posted on 5/19/20 at 5:39 pm to
quote:

BR general did a antibody test and found 4.5% positive

LINK
quote:

According to the release, BRG is reporting the following results:

- While African Americans made up only 5% of test-takers, 17% of positive results came from African American patients.

- Only one positive test was from a person under 20 years old.

- Half of BRG’s positive tests have come from people between the ages of 40-59.

- Women are more likely to get tested than men, but they test positive at the same rate.

While there are several different types of antibody tests available, BRG is using the COR2G serology test developed by Mayo Clinic. BRG says this test has a 98.6% accuracy, correctly identifying those with antibodies.

These BRG tests are not random, so there is self-selection bias in the sample, which we would expect to increase the positive rate. But for the sake of these rough calculations, let's assume that the sample of 1500 is random.

4.5% of EBR would be about 20,000 cases, and given the 219 covid deaths in EBR that puts the mortality rate at 1.1%.

But we should probably adjust for demographics. 4.5% of 1500+ tests works out to about 70 positive tests. It is stated that 17% of the positive tests were AA, yet they made up only 5% of the sample. This means 70*.17 = 12 AA positives out of ~75 samples, for a rate of 16%. Conversely, assuming most of the remaining tested were white, that gives a rate of 58/1425 = 4% among whites. Given the roughly equal demographics in EBR, that means there might be around 35,000 AA and 9000 white cases, totaling 44,000. This adjusted prevalence gives a mortality rate of 219 / 44k = 0.5%.

This data set, although not random, seems to be in line with most IFR estimates.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/19/20 at 5:44 pm to
Nice analysis.

Can also consider that Orleans has roughly twice the deaths and Ochsner is estimating 9-10% prevalence in the area.
Posted by Sasquatch Smash
Member since Nov 2007
25958 posts
Posted on 5/20/20 at 9:10 am to
Another John Ioannidis/Stanford study pre-print looking at IFR from multiple locations around the world based on antibody testing.

Ranges from 0.02 - 0.4, once corrected for demographic factors.


(Someone first linked it on the PT Board.)
This post was edited on 5/20/20 at 9:11 am
Posted by Ronaldo Burgundiaz
NWA
Member since Jan 2012
6795 posts
Posted on 5/20/20 at 9:40 am to
The more age stratification data I see, the less I care about a universal IFR. There is such a huge difference between under 60s and over 60s. The IFR for under 60's is comically low. This Danish study > LINK < put the under 70 IFR at .08%.

State governments arresting young surfers, then turning around and sending confirmed CV19 patients into nursing homes, is the most government thing in the history of government things.
Posted by Sasquatch Smash
Member since Nov 2007
25958 posts
Posted on 5/20/20 at 9:58 am to
quote:

The more age stratification data I see, the less I care about a universal IFR. There is such a huge difference between under 60s and over 60s. The IFR for under 60's is comically low. This Danish study > LINK < put the under 70 IFR at .08%.

State governments arresting young surfers, then turning around and sending confirmed CV19 patients into nursing homes, is the most government thing in the history of government things.


Agreed. Bad policy on the general quarantine and nursing home front. They should have realized this since that nursing home in WA was the canary in the coal mine that started all this shite in the USA.
Posted by klrstix
Shreveport, LA
Member since Oct 2006
3631 posts
Posted on 5/20/20 at 10:31 am to
quote:

State governments arresting young surfers, then turning around and sending confirmed CV19 patients into nursing homes, is the most government thing in the history of government things.


This is the most succinct and apropos assessment in the history of assessments...

Posted by GOP_Tiger
Baton Rouge
Member since Jan 2005
21138 posts
Posted on 5/20/20 at 11:17 am to
quote:

They should have realized this since that nursing home in WA was the canary in the coal mine that started all this shite in the USA.


It wasn't even just the US. All the European countries completely failed to protect their nursing home residents.

The good news is that it's now pretty easy. All we have to do is test all the residents and workers on a regular basis. If a resident at a home tests positive, send them to the hospital until they are over the disease.

The bad news is that I don't believe that most US states are actually doing this yet.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/20/20 at 11:20 am to
This is from the article you linked

quote:

If silent and mild infections lead to weaker antibody responses,we will underestimate the population immunity. Also, screening only for antibodies may underestimate the prevalence of infections, if cellular cytotoxicity is able to eradicate virally infected cells,as for SARS-CoV,before eliciting a humoral response8.


This is the idea I’ve been referring to regarding T cell immunity. There may be many people with mild infections clearing the infection before any significantly detected antibody response is created.

What they really need to do is go back to these prisons and military ships where there were tons of asymptomatic cases and test them for antibodies 1 month later. Let’s see how many of these asymptomatic cases or mild cases are actually making antibodies.
Posted by Ronaldo Burgundiaz
NWA
Member since Jan 2012
6795 posts
Posted on 5/20/20 at 11:30 am to
quote:

This is the idea I’ve been referring to regarding T cell immunity. There may be many people with mild infections clearing the infection before any significantly detected antibody response is created.
Indeed. I've also seen it hypothesized that children's and healthy adult's immune systems kick its arse so easily that it doesn't need to create a lot of antibodies. Would also explain why the elderly that beat CV19 have higher amounts of antibodies than younger people that beat it.
Posted by Ronaldo Burgundiaz
NWA
Member since Jan 2012
6795 posts
Posted on 5/20/20 at 11:52 am to
Routine cancer screenings have plummeted during the pandemic, medical records data show

This is (actual) bad news.

quote:

Appointments for screenings for cancers of the cervix, colon, and breast were down between 86% and 94% in March


This post was edited on 5/20/20 at 11:56 am
Posted by AmosMosesAndTwins
Lake Charles
Member since Apr 2010
19015 posts
Posted on 5/20/20 at 12:15 pm to
quote:

The good news is that it's now pretty easy. All we have to do is test all the residents and workers on a regular basis. If a resident at a home tests positive, send them to the hospital until they are over the disease.

The bad news is that I don't believe that most US states are actually doing this yet.


LA is in the process. However, you can’t just send someone to the hospital for having COVID-19 and expect them to serve as a holding facility. If the patient doesn’t need their care, they’re going to be discharged right back to us.
Posted by GOP_Tiger
Baton Rouge
Member since Jan 2005
21138 posts
Posted on 5/20/20 at 12:38 pm to
quote:

However, you can’t just send someone to the hospital for having COVID-19 and expect them to serve as a holding facility


Sure I can. Any nursing home resident who tests positive should be admitted to the hospital for observation. Any one whose health is poor enough for them to be in a nursing home probably can't be taken care of at a relative's home, and they absolutely cannot be discharged back into a nursing home.

That's what Asian countries (that are defeating the virus) are doing. In fact, in Hong Kong, all positive cases in the population (not just nursing home residents) stay in the hospital until they are negative.

I mean, it's not like our hospitals are full right now, and the hospital is the best place to monitor a positive nursing home resident (oximeter, EKG, etc.).
This post was edited on 5/20/20 at 12:39 pm
Posted by AmosMosesAndTwins
Lake Charles
Member since Apr 2010
19015 posts
Posted on 5/20/20 at 12:49 pm to
quote:

Sure I can.


Not the way it works lol
Posted by wdhalgren
Member since May 2013
5641 posts
Posted on 5/20/20 at 1:09 pm to
It's amazing how consistently article writers tend to understate or completely ignore the extent to which this was mandated policy. From the article:

quote:

U.S., federal health officials and cancer societies urged Americans to delay their routine mammograms and colonoscopies. The public has heeded those recommendations — and that’s helped lead to an apocalyptic drop in cancer screenings


For the most part, the public didn't have a choice whether or not to heed recommendations. Most couldn't schedule the screening procedure because the clinics and hospitals were shut down to elective procedures. The drastic extent of these dropoffs wasn't due to any urging, it was decreed by governments and public health authorities.
This post was edited on 5/20/20 at 1:48 pm
Posted by GOP_Tiger
Baton Rouge
Member since Jan 2005
21138 posts
Posted on 5/20/20 at 1:18 pm to
quote:

Not the way it works lol



That's literally my point. It's the way that it should work.
Posted by GOP_Tiger
Baton Rouge
Member since Jan 2005
21138 posts
Posted on 5/20/20 at 1:22 pm to
LINK

So all the stuff about Sweden having 20% antibodies, etc. was completely wrong. In the capital, where the epidemic has been the worst, the antibody level was tested at 7.3%.

Of course, it would be higher now, since that was the state of things in April, but it would not appear that Sweden is anywhere near herd immunity.
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