re: Anyone on Ozempic? Effective? Any side effects?

Semaglutide peptides. It's cheaper than going to the Dr for it if you want it.

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Does it really make people that would usually eat whenever just all of a sudden not hungry? I have a hard time trusting something like that.

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Peptides have been studied for a long time. Ozempic has been around for 7 years, are there risks? Probably. Now I’m not speaking to you directly when I say this, but, the guys who say just eat right and go to the gym… great, good for you. You guys are much better than the rest of us and we are very proud of you. Probably the same guys that make fun of morbidly obese people who feel hopeless because it’ll take them years to lose weight and that’s if they stick to a new lifestyle for that period of time.

A lot of people for a variety of reasons have a really, really hard time completely changing a lifestyle like that, so they have had to suffer the consequences. But now there’s a medication that makes it infinitely easier, so most people will opt for that. It’s like saying “don’t take Naltrexone, just stop drinking” to an alcoholic. Or “don’t take Trazodone just start sleeping better.” No reason to not use shite that makes it easier if it’s available.

Elvis Presleys daughter died from gastric surgery.

Per wikipedia -

On January 12, 2023, at around 10:30 a.m., Presley suffered a cardiac arrest at her home in Calabasas, California. Her heart was restarted after CPR was administered en route to West Hills Hospital in Los Angeles, but she died later that day at the age of 54.[According to her autopsy report, Presley died of "small bowel obstruction" caused by a bariatric surgery she had undergone.

Im type 2 diagnosed in 2015. A1c of 11 weighed 165 cut out carbs to less than 100 a day, in 3 months I lost 15 lbs today Im 146 which is what i weighed in high school.

My last A1c was 6.0 I don't take any meds. hardly any carbs in my diet if there is it's broccoli and that's rare high fat carnivore diet

You can control both diabetes and weight with a lifestyle change plenty people do it
big pharma is not interested in us getting well they want us to stay sick

GLP-1 agonists have been around for several decades. Not new. We know they are very safe. Roughly 1 in 8 adults in the US have taken a GLP-1 agonist, and about half of that amount are currently taking one. Sample size is very large. Prevalence of serious side effects is minimal at worst and possibly non existent. With that many people taking it, there can easily be assumptions of causation that are incorrect. Lots of people that take an aspirin every day have heart attacks. That doesn’t mean the aspirin causes the heart attack. Plenty of lawyers are trying to profit from this, so there will be ample microscopes on it in the coming years. I’m not saying there aren’t side effects or potentially severe side effects. If there are, they are very small in number and the risks are far outweighed by the benefits.

GLP-1 agonists help raise GLP-1 levels to normal levels in individuals that don’t produce enough GLP-1. GLP-1 regulates hunger and “food noise.” Once the GLP-1 level is raised to a normal level, hunger is regulated properly as opposed to it not being regulated properly with a deficit. The sensation of hunger is too powerful for the vast majority of people. “Will power” is a misguided concept when fighting biology. Heart disease medications have side effects, but those meds continue to be prescribed and taken to protects patients with heart disease. This is no different. It’s driven by biology. Proper treatment of obesity should ALWAYS also include lifestyle changes such as diet and exercise.

Like many drugs, some choose to abuse these medicines. That has complicated how many view these drugs. Lots of people believe these drugs should only be for diabetics. Treating obesity is absolutely just as important as treating diabetes. Imagine if everyone that currently has diabetes had access to and took a GLP-1 agonist before developing diabetes. There would be very little diabetes today. Imagine how much money would be saved by avoiding dialysis costs alone(probably the single largest healthcare cost in our system). Obesity causes so many other diseases and ailments. Obesity is treatable. Treating obesity is both direct line treatment of a disease AND preventative medicine against the majority of other diseases.

Society is struggling with this because of the social stigma associated with obesity. That is a social construct and it inhibits progress in obesity medicine.

If you struggle to maintain a healthy weight(this is lower than most realize), see a doctor that specializes in obesity medicine. Look for an MD with ASMBS and DABOM credentials.

Fun fact: these meds are proving to break addiction of many forms. There is a very real impact on the reward center in the brain. Alcoholism, drug addiction, gambling, nail biting, etc are being defeated by these meds.

Wife lost 77 lbs in 11 months. Shes to skinny imo now. Shes 122. I told her to wein herself off of the shite! You do have to try and change habits etc. Or like anything else it wont work

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Wife lost 77 lbs in 11 months. Shes to skinny imo now. Shes 122. I told her to wein herself off of the shite! You do have to try and change habits etc. Or like anything else it wont work

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Her GLP-1 levels were too low before the meds. The meds corrected her deficiency and she lost weight as a result. If she stops taking the meds, that GLP-1 deficit will almost certainly occur again. GLP-1 deficit is what drives food noise and hunger.

I’m not saying getting off the meds and keeping the weight off is impossible, but it is very difficult and statistically very unlikely. Obesity is a perpetual disease that requires perpetual treatment. Perhaps some combination of diet and exercise may be sufficient for her, but if it wasn’t sufficient prior to the meds and losing weight then it likely won’t be sufficient after losing the weight and being off the meds.

Would you advise her to stop taking heart disease medicine because the meds have been working for some period of time? Food for thought. As always, consult a doctor that specializes in obesity medicine for the best care plan. DABOM stands for Diplomat of the American Board of Obesity Medicine. There are a lot of docs(the majority that are prescribing it today) writing for these meds without truly understanding the complexity of the disease and proper treatment plans of it.

“Semaglutide has been around for decades”

True but it was smaller doses used for type 2 diabetes.The larger dose as Wygovy was approved in 2021,I believe.
I would imagine the larger dose used for longer periods of time would increase the risk of side effects.
My position on drugs is that they all have side effects,some more serious than others so it is best to avoid them if at all possible.
Ex.-Zantac which was very popular for a long time was pulled off the market after 16 years for unacceptable cancer risk.(It contained NDMA).

I’m 73 and so far have not required any medications,all my labs and BP are normal,so I’m very fortunate.
I would like to lose some weight and I understand the appeal of a “magic pill” but to me the risks are unacceptable.

My weight doesn’t qualify me for gastric sleeve surgery but if it did that’s the way I would go (not gastric bypass).

Gastric sleeve surgery carries minimal risk,certainly not bowel obstruction,pancreatitis,thyroid cancer or blindness.

I know 6 people that had gastric sleeves,all lost significant amounts of weight over the following year?Unfortunately 2-3 years later,5 of the 6 regained their weight and were back where they were before .
Same thing is going to happen to those that eventually get off Wygovy,in most cases.

I am just using it as a tool. I am confident I can keep it off. I am not confident I can lose it.