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re: Xyosted vs Testosterone Cyp

Posted on 4/1/26 at 11:06 am to
Posted by lsu777
Lake Charles
Member since Jan 2004
38031 posts
Posted on 4/1/26 at 11:06 am to
quote:


This is not how pharma works, no matter how much yall want to believe it.


well then why are doctors pushing shite like this without doing their own research? are they that lazy, incompetent or just don't give a frick and push it because they like the rep?
Posted by Arthur Bach
Member since Jul 2016
3193 posts
Posted on 4/1/26 at 12:01 pm to
quote:

well then why are doctors pushing shite like this without doing their own research? are they that lazy, incompetent or just don't give a frick and push it because they like the rep?


I mean-lazy and incompetent is part of it. I think you’re generalizing things, though. What are other things you’re talking about?
Posted by lsu777
Lake Charles
Member since Jan 2004
38031 posts
Posted on 4/1/26 at 12:11 pm to
quote:

I mean-lazy and incompetent is part of it. I think you’re generalizing things, though. What are other things you’re talking about?


im talking in general but in this specific case....why any competent doctor would push xyosted over generic cypionate. even if you liked your customers enanthate there is the brand name Delatestryl

not to mention with just goodrx and no insurance-

basic generic testosterone enanthate available for $32/5ml

test cyp is $48 per 10ml vial


so again why would a doctor randomly push a medication when obviously they know very little about it, there is no benefit and its more expensive?
Posted by DarthRebel
Tier Five is Alive
Member since Feb 2013
25819 posts
Posted on 4/2/26 at 8:38 am to
quote:

So are are these reps telling the MD’s that Ethanate does more than cypionate or something? Still really weird that the pen maxes at 100mg. Not one guy that I know is on a dose that low.


That is where most doctors fail, when compared to a urologist or T/Men's Health clinic. I told him my dosage range over the last few years gas been 180 to 210. Oh we will give you the 100mg then

100mg would technically put you in normal range sure, but that is a waste of money. If you are going the TRT route, you want to be near 1000 for Total T.

Posted by ronricks
Member since Mar 2021
12169 posts
Posted on 4/2/26 at 8:54 am to
quote:

If you are going the TRT route, you want to be near 1000 for Total T.


Told people this on here once and got absolutely skewered by a bunch of know nothing skinny fat fricks who think eating Chick Fil A is 'healthy'
Posted by DarthRebel
Tier Five is Alive
Member since Feb 2013
25819 posts
Posted on 4/2/26 at 9:06 am to
quote:

This is not how pharma works, no matter how much yall want to believe it.


Either money or



They are not doing it for the hell of it.
Posted by Arthur Bach
Member since Jul 2016
3193 posts
Posted on 4/2/26 at 9:54 am to
this isn’t 1996

Xyosted (subcutaneous testosterone enanthate auto-injector) has a few key advantages over traditional testosterone cypionate IM injections:
Convenience & delivery — Xyosted is a weekly subcutaneous auto-injector (similar to an EpiPen), so you’re using a small needle into belly fat rather than a larger IM needle into the glute or delt. Much easier to self-administer.
Steadier levels — Subcut absorption tends to produce more stable serum testosterone levels with fewer peaks and troughs compared to IM cypionate, which can cause a spike post-injection and a dip before the next one. That means fewer mood/energy swings tied to your injection schedule.
Lower estrogen conversion — Studies have shown subcut testosterone delivery may result in less aromatization (conversion to estradiol), which could mean fewer estrogen-related side effects like water retention or gynecomastia.
Less polycythemia risk — The steadier levels may reduce the degree of hematocrit/red blood cell elevation compared to IM, though monitoring is still recommended.
The trade-off — Xyosted is significantly more expensive, and not all insurance covers it well. Testosterone cypionate IM is generic and dirt cheap by comparison. Some guys on TRT also prefer compounded subcut cypionate (drawn from a vial, injected subcut with an insulin syringe) as a middle-ground approach — you get the subcut benefits at generic pricing.
Worth asking your prescriber about if the peak/trough swings on cypionate are bugging you.????????????????
Posted by Uncle JackD
Member since Nov 2007
59564 posts
Posted on 4/2/26 at 10:06 am to
Every benefit you listed, even though those are very exaggerated, can be also achieved by administering dirt cheap TestC. Those benefits are not specific to TestE but the way it’s being given.

Like I said, if your insurance covers it, go for it. More power to you. But the dosage sucks balls and 9/10 times the insurance will not cover it.

At the end of the day, you’re paying 20x the cost for a stupid auto injector vs using a $.25 SubQ needle.
This post was edited on 4/2/26 at 10:15 am
Posted by Arthur Bach
Member since Jul 2016
3193 posts
Posted on 4/2/26 at 10:54 am to
Someone ask this guys urologist for the reasoning.

I have shite to do today
Posted by dangerousdon
Baton Rouge
Member since Jun 2008
662 posts
Posted on 4/2/26 at 11:27 am to
As soon as I see the Urologist I’ll definitely ask. In the meantime I messaged his office and let them know I prefer test c.

I’m not overly impressed with the doc anyway and as soon as I get started on something I’ll probably look for another doctor. If another will take me on. I already have the tests done with this Urologist so I’m seeing it through for now.
Posted by rooster108bm
Member since Nov 2010
3234 posts
Posted on 4/13/26 at 1:23 pm to
quote:

xyosted is testosterone enanthate in an auto injector.....it has a half life of 8 days vs 7 for cypionate


Cypionate has a longer half life than enanthate.
Posted by lsu777
Lake Charles
Member since Jan 2004
38031 posts
Posted on 4/13/26 at 2:48 pm to
quote:

Cypionate has a longer half life than enanthate.



you are right, i typed it backwards and ftr clinically enanthate is ~7days but all of that depends on the carrier oil, where you inject it, how deep etc.

but they are roughly the same. the only advantage of enanthate is it is easier for them to make at 300mg/ml without causing PIP.
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