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re: Anyone on here ever been diagnosed with leukemia?

Posted on 10/13/20 at 8:36 pm to
Posted by Chucktown_Badger
The banks of the Ashley River
Member since May 2013
31306 posts
Posted on 10/13/20 at 8:36 pm to
That NFL crucial catch commercial has chuck pagano talking about his wife seeing the bruises and making him get checked. He had acute promyelotic leukemia, which I'm not really familiar with.
Posted by LSUTigerDoc
Baton Rouge
Member since Oct 2008
582 posts
Posted on 10/13/20 at 8:43 pm to
quote:

That NFL crucial catch commercial has chuck pagano talking about his wife seeing the bruises and making him get checked. He had acute promyelotic leukemia, which I'm not really familiar with.


A fascinating disease characterized by a genetic mutation in the white blood cells at the retinoic acid receptor gene locus. Although this is a variant of acute myeloid leukemia, this subset of aml actually has an amazingly good prognosis. Due to the driver mutation for this disease, it can actually be successfully treated with all-trans retenoic acid, a derivative of vitamin A. More interesting is the fact that arsenic (oral or intravenous) is not only very effective in the therapy of this disease but also FDA approved for use.
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