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Hydroxychloroquine showed no benefit, more deaths

Posted on 4/21/20 at 4:45 pm
Posted by Man With A Plan
Member since Nov 2019
899 posts
Posted on 4/21/20 at 4:45 pm
quote:

Malaria drug hydroxychloroquine showed no benefit in a large study of its use at U.S. veterans hospitals, researchers say.


Hydroxychloroquine has garnered global attention during the coronavirus pandemic, most notably from President Trump, who touted it as a potential treatment.

The research, which was published in the medRxiv online depository, evaluated data from 368 COVID-19 patients.

quote:

“We performed a retrospective analysis of data from patients hospitalized with confirmed SARS-CoV-2 infection in all United States Veterans Health Administration medical centers until April 11, 2020,” the researchers explained. Some 97 patients had been treated with just hydroxycholoroquine, 113 were treated with hydroxycholoroquine and the antibiotic azithromycin and 158 received “standard supportive management” for COVID-19.

quote:

The two primary outcomes analyzed in the study were death and the need for ventilation.

About 28 percent who were given hydroxychloroquine plus usual care died, versus 11 percent of those getting routine care alone. About 22 percent of those getting the drug plus azithromycin died too, but the difference between that group and usual care was not considered large enough to rule out other factors that could have affected survival.


quote:

Researchers did not track side effects but noted hints that hydroxychloroquine might have damaged other organs. The drug has long been known to have potentially serious side effects, including altering the heartbeat in a way that could lead to sudden death.

Earlier this month, scientists in Brazil stopped part of a hydroxychloroquine study after heart rhythm problems developed in one-quarter of people given the higher of two doses being tested.

Fox News link

I must admit I was wrong about this, very concerning study here.
This post was edited on 4/21/20 at 5:07 pm
Posted by Powerman
Member since Jan 2004
164929 posts
Posted on 4/21/20 at 4:47 pm to
Looks like remdesivir might be more promising.
Posted by Man With A Plan
Member since Nov 2019
899 posts
Posted on 4/21/20 at 4:47 pm to
quote:

Hydroxychloroquine made no difference in the need for a breathing machine, either.

“In this study, we found no evidence that use of hydroxychloroquine, either with or without azithromycin, reduced the risk of mechanical ventilation in patients hospitalized with Covid-19,” the researchers said. “An association of increased overall mortality was identified in patients treated with hydroxychloroquine alone. These findings highlight the importance of awaiting the results of ongoing prospective, randomized, controlled studies before widespread adoption of these drugs.”
Posted by Tigahs24Seven
Communist USA
Member since Nov 2007
13182 posts
Posted on 4/21/20 at 4:48 pm to
Fake news...how much given? When given?
Facts to shut up.
Posted by Man With A Plan
Member since Nov 2019
899 posts
Posted on 4/21/20 at 4:49 pm to
quote:

Looks like remdesivir might be more promising.

Hope so, the way this virus mutates, and the fact we have no immunity means vaccines probably won't be possible. I am convinced this was a Chinese bio weapon created in a lab.
Posted by HailHailtoMichigan!
Mission Viejo, CA
Member since Mar 2012
71357 posts
Posted on 4/21/20 at 4:49 pm to
It was worth a shot to try


Luckily we are seeing other drugs get positive results
Posted by Man With A Plan
Member since Nov 2019
899 posts
Posted on 4/21/20 at 4:50 pm to
quote:

It was worth a shot to try

The study found it leads to more deaths, so I would try something else.
Posted by Tiguar
Montana
Member since Mar 2012
33131 posts
Posted on 4/21/20 at 4:51 pm to
garbage study, implicit bias given the retrospective nature

brazilian study showed a significantly reduced risk of hospitalization if given to outpatients in the first 7 days
Posted by gthog61
Irving, TX
Member since Nov 2009
71001 posts
Posted on 4/21/20 at 4:51 pm to
Oh so all of the favorable reports from other tests are undone by one

smells like bullshite
Posted by Tiguar
Montana
Member since Mar 2012
33131 posts
Posted on 4/21/20 at 4:52 pm to
quote:

smells like bullshite


because it is
Posted by Tmcgin
BATON ROUGE
Member since Jun 2010
5899 posts
Posted on 4/21/20 at 4:52 pm to
Fake News = This makes my ears hurt

Its a lazy response these days .....really lazy
Posted by Pandy Fackler
Member since Jun 2018
19125 posts
Posted on 4/21/20 at 4:52 pm to
It's a media driven lie designed to make the president of the United states look like a fool.

The drug works. The French said so and so did a podiatrist on you-tube. But when you think about it, it doesn't really need to work because it's all one big hoax designed to get President Trump out of office. I saw a tweet that said so and I also heard it in talk radio.
Posted by Janky
Team Primo
Member since Jun 2011
35957 posts
Posted on 4/21/20 at 4:52 pm to
Something sounds fricky.
Posted by HailHailtoMichigan!
Mission Viejo, CA
Member since Mar 2012
71357 posts
Posted on 4/21/20 at 4:52 pm to
What are you babbling about?

It would have been negligent not to try this when you had doctors all over the world reporting positive results
Posted by HailHailtoMichigan!
Mission Viejo, CA
Member since Mar 2012
71357 posts
Posted on 4/21/20 at 4:55 pm to
quote:

It's a media driven lie designed to make the president of the United states look like a fool.

The drug works. The French said so and so did a podiatrist on you-tube. But when you think about it, it doesn't really need to work because it's all one big hoax designed to get President Trump out of office. I saw a tweet that said so and I also heard it in talk radio.


Imagine being *giddy* that a drug that was showing anecdotal promise ended up being not as effective as thought.

You have pretty severe problems if this makes you happy.
Posted by fillmoregandt
OTM
Member since Nov 2009
14368 posts
Posted on 4/21/20 at 4:55 pm to
muh anedoctal evidence
Posted by Soup Sammich
Member since Aug 2015
3301 posts
Posted on 4/21/20 at 4:55 pm to
Acosta is about to lead the lynch mob to the White House once he gets wind of this.
Posted by TejasHorn
High Plains Driftin'
Member since Mar 2007
11587 posts
Posted on 4/21/20 at 4:55 pm to
Funny how hydro talk just kind of went away.
Go figure.

Seriously though, those being treated with it for legit reasons are undoubtedly thankful trump isn't pushing it anymore.
This post was edited on 4/21/20 at 4:56 pm
Posted by dcbl
Good guys wear white hats.
Member since Sep 2013
30991 posts
Posted on 4/21/20 at 4:55 pm to
quote:

brazilian study showed a significantly reduced risk of hospitalization if given to outpatients in the first 7 days


all the studies are showing this
Posted by YF12
Ottobaan
Member since Nov 2019
4451 posts
Posted on 4/21/20 at 4:56 pm to
So more than twice as many people died taking harmless drugs compared to taking no drugs at all?

And that makes sense why exactly?

Sounds sketchy as frick
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