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Started By
Message
Biology, Chemist and Biochemist OTers: Help me understand weight loss.
Posted on 4/3/17 at 7:54 am
Posted on 4/3/17 at 7:54 am
I was watching a video on Ketosis. The guy was explaining it using alot of biochemistry jargon, but I still was able to interpret it in my own way.
I deduced that your body runs of a primary fuel and a back up fuel. Glucose is the primary fuel. Glucose is produced in your body from carbs and sugar. If the "tank" for glucose fuel fills, due to you not burning it, the excess glucose is then stored into fat cells. Your body will only burn these fat reserves when the glucose "tank" is empty.
I know it is alot more complex than that, but is this a good and simple way of understanding a complex biochemical process?
I deduced that your body runs of a primary fuel and a back up fuel. Glucose is the primary fuel. Glucose is produced in your body from carbs and sugar. If the "tank" for glucose fuel fills, due to you not burning it, the excess glucose is then stored into fat cells. Your body will only burn these fat reserves when the glucose "tank" is empty.
I know it is alot more complex than that, but is this a good and simple way of understanding a complex biochemical process?
22
Posted on 4/3/17 at 7:55 am to MontyFranklyn
Do you even lift, bro?
Posted on 4/3/17 at 7:55 am to MontyFranklyn
That's how I understand it. Some say it is how our body should operate.
ETA:
Also, sugar is processed by the liver, and enters the blood stream causing spikes in blood sugar. That also causes blood vessels to inflame, which can lead to blockages.
ETA:
Also, sugar is processed by the liver, and enters the blood stream causing spikes in blood sugar. That also causes blood vessels to inflame, which can lead to blockages.
This post was edited on 4/3/17 at 7:58 am
Posted on 4/3/17 at 7:56 am to MontyFranklyn
Yes
Read "Protein Power"
Goes into it deeper
Read "Protein Power"
Goes into it deeper
Posted on 4/3/17 at 8:02 am to MontyFranklyn
Move more, eat less.... 
Posted on 4/3/17 at 8:02 am to MontyFranklyn
Calories in, calories out baw
Posted on 4/3/17 at 8:03 am to MontyFranklyn
Consume less calories than you burn
Posted on 4/3/17 at 8:08 am to MontyFranklyn
My understanding isn't necessarily that you will burn glucose first. It is just an "easier" source of fuel. It can be broken down into energy more quickly. Therefore, at higher rates of physical exertion, you will burn glucose energy stores. When you run low, you get that bonked/drained feeling and you have no more fuel in the tank (fat can't break down fast enough to supply the energy). At lower rates of energy exertion, your body can run on fat energy stores. It's all about your heart rate and metabolic zone.
This is where people see that "fat burning zone" on the treadmill and think they need to work out in that zone to burn their fat. That's not necessarily a truthful idea. You don't lose weight 'better' just because you burned fat in that zone. You are just utilizing that as a source of energy at that level of physical exertion. In the end, you burned X amount of calories. If you burned X amount of calories in the "glucose burning zone" you'd have done the same amount of good in terms of weight loss. The source of energy just becomes more important in endurance sports like running a marathon or something.
I don't claim to be an expert. My input is about as good as any other bro-science out there. Just from a different perspective when researching running/triathlon nutrition.
This is where people see that "fat burning zone" on the treadmill and think they need to work out in that zone to burn their fat. That's not necessarily a truthful idea. You don't lose weight 'better' just because you burned fat in that zone. You are just utilizing that as a source of energy at that level of physical exertion. In the end, you burned X amount of calories. If you burned X amount of calories in the "glucose burning zone" you'd have done the same amount of good in terms of weight loss. The source of energy just becomes more important in endurance sports like running a marathon or something.
I don't claim to be an expert. My input is about as good as any other bro-science out there. Just from a different perspective when researching running/triathlon nutrition.
This post was edited on 4/3/17 at 8:17 am
Posted on 4/3/17 at 8:15 am to MontyFranklyn
Yes. That is the simplest way to put it. This is why it is best to workout in the morning. Your fuel reserves or glucose are at your lowest. You will burn more fat faster in the AM.
Posted on 4/3/17 at 8:20 am to MontyFranklyn
Wanna lose wt?
I have a foolproof 2-step weight loss program.
Step #1 - Eat Less.
Step #2 - Move around more.
I have a foolproof 2-step weight loss program.
Step #1 - Eat Less.
Step #2 - Move around more.
Posted on 4/3/17 at 8:21 am to MontyFranklyn
I'm none of those in the title, but my company just did a 17 person fat loss diet challenge. We had 8 people who did very well. We all were calipered by the same person beginning and end. Went for two months.
There was a few interesting things.
The top performers all lost roughly the same amount of body fat but different amounts of weight. We all lost between 1# and 1.5# of fat per week.
The two winners did not starve themselves. They both were the only ones to plan and measure their food out. The person who lost the most weight was visibly thinner, but lost less fat.
Many did different diets and had similar success. Do not drop your calories too low. Eat and exercise. Cut sugar and try to loose 1.5 pounds a week after week one. Week one would be a little more.
The winners both lost 12# compared to the top loss at 28# over two months. Winners were able to lift weights, do some cardio, and they timed their meals.
There was a few interesting things.
The top performers all lost roughly the same amount of body fat but different amounts of weight. We all lost between 1# and 1.5# of fat per week.
The two winners did not starve themselves. They both were the only ones to plan and measure their food out. The person who lost the most weight was visibly thinner, but lost less fat.
Many did different diets and had similar success. Do not drop your calories too low. Eat and exercise. Cut sugar and try to loose 1.5 pounds a week after week one. Week one would be a little more.
The winners both lost 12# compared to the top loss at 28# over two months. Winners were able to lift weights, do some cardio, and they timed their meals.
Posted on 4/3/17 at 8:22 am to MontyFranklyn
Basically your body is going to burn carbs unless there are no carbs. Then it will start burning your fat stores.
So if you limit your carbs you'll be able to lose weight faster. If you eat a pizza and then go to the gym and run 6 miles, you're just going to be burning off the carbs from the pizza, not fat stores.
It's a little more complicated than that, but if you use that as a general guide, you'll lose fat a lot faster.
So if you limit your carbs you'll be able to lose weight faster. If you eat a pizza and then go to the gym and run 6 miles, you're just going to be burning off the carbs from the pizza, not fat stores.
It's a little more complicated than that, but if you use that as a general guide, you'll lose fat a lot faster.
This post was edited on 4/3/17 at 8:25 am
Posted on 4/3/17 at 8:32 am to MontyFranklyn
it isn't rocket science. Eat less, move more. Lose weight every time
Posted on 4/3/17 at 8:41 am to MontyFranklyn
Posted on 4/3/17 at 8:45 am to MontyFranklyn
That is exactly how I understand it. That is why high protein low carb diets are so effective.
Posted on 4/3/17 at 9:12 am to MontyFranklyn
Watch this. It will show you how your body gets rid of fat. This is based on regular eating and not ketosis.
This video is on ketosis. It is not really a scientific approach but info is there to get a good grasp on what is happening.
This video is more scientific but has a really stupid background music.
Ketosis is just a different energy system. Fat has more potential energy in a gram than glucose does but does not provide the "instant" energy that glucose does. You have to deplete your glucose to get into ketosis. If you have ever tried out ketosis you will see that you will "level out" your energy levels and have a sustained release of energy throughout the day instead of peaks from glucose. There is no doubt that glucose is very beneficial for exercising but IMO a timed carb meal is better than eating carbs throughout the day. I believe the diet is called TKD where you would time your carbs right before or after the workout and be in ketosis the rest of the time.
I don't know about the overall "weight" loss of ketosis vs diets with carbs but I do hold on to more weight with carbs. I get bloated.
The way I approach my diet is to be in mindset of ketosis but not worrying about being in ketosis. I have my cheat meals throughout the week but I treat them as treats. I try to eat a fairly large carb/calorie meal before days where I deadlift or squat. The other days, I just consume a little bit of carbs. I am in maintenance right now but if I were to cut, I'd just reduce the carbs a little bit more and add in some cardio if the reduction of carbs slows down.
Basically, treat your food as fuel and use it how it was intended. Carbs are for energy. If you don't require the energy the carbs provide, don't eat them or eat them sparingly.
This video is on ketosis. It is not really a scientific approach but info is there to get a good grasp on what is happening.
This video is more scientific but has a really stupid background music.
Ketosis is just a different energy system. Fat has more potential energy in a gram than glucose does but does not provide the "instant" energy that glucose does. You have to deplete your glucose to get into ketosis. If you have ever tried out ketosis you will see that you will "level out" your energy levels and have a sustained release of energy throughout the day instead of peaks from glucose. There is no doubt that glucose is very beneficial for exercising but IMO a timed carb meal is better than eating carbs throughout the day. I believe the diet is called TKD where you would time your carbs right before or after the workout and be in ketosis the rest of the time.
I don't know about the overall "weight" loss of ketosis vs diets with carbs but I do hold on to more weight with carbs. I get bloated.
The way I approach my diet is to be in mindset of ketosis but not worrying about being in ketosis. I have my cheat meals throughout the week but I treat them as treats. I try to eat a fairly large carb/calorie meal before days where I deadlift or squat. The other days, I just consume a little bit of carbs. I am in maintenance right now but if I were to cut, I'd just reduce the carbs a little bit more and add in some cardio if the reduction of carbs slows down.
Basically, treat your food as fuel and use it how it was intended. Carbs are for energy. If you don't require the energy the carbs provide, don't eat them or eat them sparingly.
This post was edited on 4/3/17 at 9:14 am
Posted on 4/3/17 at 9:30 am to MontyFranklyn
Don't do it for long periods of time. It can be hard on your kidneys.
Posted on 4/3/17 at 3:36 pm to MontyFranklyn
As others have said, it's all about caloric burn. a calorie is 1 unit of energy. If you eat 1000 calories and burn 1200, the reserve 200 comes from your fat cell stores. Weight loss is seriously as easy as that.
Posted on 4/3/17 at 3:47 pm to MontyFranklyn
Basically, your body is constantly breaking down glucose. Glucose gets oxidized and goes through glycolysis, the Citric Acid Cycle and the Electron Transport Chain. Fatty Acid Oxidation can feed into these pathways.
At the Citric Acid Cycle, oxaloacetate combines with ACOA to form citrate. If you starve yourself, however, there will be a decrease in oxaloacetate production, which means it can't combine with acetyl COA to produce citrate and produce ATP this way.
Your body, to make up for the discrepancy, begins funneling in fat to burn as energy. Ketone bodies are important for brain and vital organ function if you're starving.
To make a long story short, if you're low on sugar, either glucose or glycogen, your body burns fat. This is ketosis. It keeps funneling in triglycerides from adipose tissue.
It's sound scientifically to lead to weight loss.
Sympathetic nervous system neurotransmitters also operate in this way. I think this is a way to lose weight.
At the Citric Acid Cycle, oxaloacetate combines with ACOA to form citrate. If you starve yourself, however, there will be a decrease in oxaloacetate production, which means it can't combine with acetyl COA to produce citrate and produce ATP this way.
Your body, to make up for the discrepancy, begins funneling in fat to burn as energy. Ketone bodies are important for brain and vital organ function if you're starving.
To make a long story short, if you're low on sugar, either glucose or glycogen, your body burns fat. This is ketosis. It keeps funneling in triglycerides from adipose tissue.
It's sound scientifically to lead to weight loss.
Sympathetic nervous system neurotransmitters also operate in this way. I think this is a way to lose weight.
This post was edited on 4/3/17 at 3:53 pm
Posted on 4/3/17 at 4:03 pm to MontyFranklyn
quote:
I deduced that your body runs of a primary fuel and a back up fuel. Glucose is the primary fuel. Glucose is produced in your body from carbs and sugar. If the "tank" for glucose fuel fills, due to you not burning it, the excess glucose is then stored into fat cells. Your body will only burn these fat reserves when the glucose "tank" is empty.
Pretty good synopsis. However it is a little more complicated than that. It's not either/or when you're exercising, you're burning both fat and glucose.
The intensity of exercise can dictate in what ratio your body burns glucose and fat. During low intensity exercise your body will tend to burn less fat. High intensity interval training you'll burn more.
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