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Started By
Message
New MS Drug Ocrevus Wins FDA Approval
Posted on 3/29/17 at 3:05 pm
Posted on 3/29/17 at 3:05 pm
quote:
While it's not a cure, it's one more weapon to use to help some of the 400,000 people with MS. In trials of 1,600 volunteers, it cut relapses in patients with the most common form of MS by nearly half compared with an older drug called Rebif.
quote:
It will be on the market within two weeks, and will cost $65,000 a year, the company said. That's similar to the cost of Rebif, a 14-year-old drug now widely used to treat MS.
LINK
quote:
Given every six months by IV infusion...
$65,000 A YEAR for just two treatments!!! Damn, I would be suffering like hell. I know if you had insurance it would like ly cover much of the cost, what if you were didn't and happened to get diagnosed with this. Drug pricing is ridiculous.
Posted on 3/29/17 at 3:11 pm to Hammond Tiger Fan
quote:
It will be on the market within two weeks, and will cost $65,000
quote:
some of the 400,000 people with MS.
That's a hell of a market cap... Roche thinks their drug is worth $26 Billion dollars for the kids keeping count at home.
This post was edited on 3/29/17 at 3:17 pm
Posted on 3/29/17 at 3:12 pm to Hammond Tiger Fan
quote:
MS
A monkey scrotum?
Posted on 3/29/17 at 3:15 pm to Hammond Tiger Fan
quote:
and will cost $65,000 a year
Jesus.
Just think how much a "cure" for cancer (or something like that) would cost. Drug companies would like charge millions.
Posted on 3/29/17 at 3:17 pm to NYNolaguy1
quote:
$26 Billion dollars for the kids keeping count at home.
Probably not as great as a payout after research costs. But companies need to get paid off to keep investing in wonderful drugs to help quality of life.
Posted on 3/29/17 at 3:20 pm to ksayetiger
quote:
Probably not as great as a payout after research cost
I guess it's easy to set a monster high price when the alternative is a miserable existence and early death...
Posted on 3/29/17 at 3:38 pm to NYNolaguy1
Is it progress or just "another drug" ending in "mab"?
If it benefits, great? But those mess have sit tons of side effects. Is this just another more costly version of the same thing?
I've not read enough on this so I am actually asking.
If it benefits, great? But those mess have sit tons of side effects. Is this just another more costly version of the same thing?
I've not read enough on this so I am actually asking.
Posted on 3/29/17 at 3:42 pm to LSU alum wannabe
quote:
Is it progress or just "another drug" ending in "mab"?
If it benefits, great? But those mess have sit tons of side effects. Is this just another more costly version of the same thing?
I've not read enough on this so I am actually asking
From what I have read it's effective in half of the people with the most prevalent form of multiple schlerosis. So for a good portion yes it's a game changer, according to the manufacturer.
The rest, it's wasted $$$.
Posted on 3/29/17 at 3:52 pm to LSU alum wannabe
quote:
Is it progress or just "another drug" ending in "mab"?
Do you know for what "mab" stands? Just another mab? What the frick?
Posted on 3/29/17 at 3:58 pm to guedeaux
"Mab" = monoclonal antibody
Posted on 3/29/17 at 4:13 pm to Hammond Tiger Fan
Thanks for the heads-up.
Just bought some Roche stock. What do you baws think my target is, 400?
Just bought some Roche stock. What do you baws think my target is, 400?
Posted on 3/29/17 at 4:25 pm to Hammond Tiger Fan
An interesting thing about this drug is that there is already a monoclonal antibody called rituximab that targets the same receptor, CD20 (a protein on immune cells). The difference is that ocrevus is a humanized antibody while rituximab is a mouse/human chimeric antibody. How much difference that makes, I don't know as I'm not an antibody expert. I do know that ocrelizumab will have patent protection longer, potentially explaining the push to have it approved.
Posted on 3/29/17 at 4:31 pm to Hammond Tiger Fan
It really is a shame. Don't blame the doctors and pharmacists. It's the manufacturers that set these obscene prices.
Insulin cost insurers $25 fifteen years ago and now it's at least $200-$450 a month per patient.
There is a cure for Hep C that would bankrupt the healthcare system if everyone could get it.
Insulin cost insurers $25 fifteen years ago and now it's at least $200-$450 a month per patient.
There is a cure for Hep C that would bankrupt the healthcare system if everyone could get it.
Posted on 3/29/17 at 7:46 pm to NYNolaguy1
quote:
That's a hell of a market cap... Roche thinks their drug is worth $26 Billion dollars for the kids keeping count at home.
Roche is the leader in the medical field putting profits back into R&D. 20%.
Posted on 3/29/17 at 8:07 pm to OKellsBells
quote:
Insulin cost insurers $25 fifteen years ago and now it's at least $200-$450 a month per patient.
NPH and Regular as well as 70/30 are available over the counter at Wal Mart for $25/1000 units.
Also, Sanofi's 100u/mL insulin glargine (lantus) has a direct competitor (Basaglar) and is now wholesaling to some certain nationally-designated pharmacies for very cheap. I have no idea if/when the price will drop for cash pay at normal pharmacies, but if you're indigent or near it, you can get it for next to nothing now.
A step in the right direction? I hope so...
Posted on 3/29/17 at 8:24 pm to Hammond Tiger Fan
quote:
Drug pricing is ridiculous
It is. But to be totally fair, they just mapped out a genetically engineered antibody that will specifically target the smallest amount of things in your body to prevent the disease from worsening while minimizing its effects.
Generally speaking, the more that something is like our body, the harder it is to fix with a medicine, because then the medicine targets things similar to our body. Bacteria? That's easy. They work way differently than our bodies. That's why penicillin isn't particularly toxic to the human body, comparatively speaking. Here you've got an autoimmune disorder. That is, your body attacks itself. Now you have to have a drug that targets part of your body that's gone rogue (with no clear reason why) with the most limited spectrum possible. To do that is quite difficult. And it's a small target population. Those things combined make this really prone to high cost.
But what is this better than? This is better than drugs that totally wipe out the immune system. Those will also alleviate MS symptoms but come with the risk of your body, well, having basically no/limited immune system. The reward is now well worth the risk for treating.
But it's so expensive. The more of these drugs that are able to be made, the more we learn about the process of monoclonal antibody production. It's a wildly expensive process, but? the end-results, price aside, are phenomenal and are truly changing healthcare. This isn't a company taking a naturally occurring large protein/hormone/etc and mass producing it.
Could they sell it for cheaper? Probably. Is there a patient assistance program? Almost definitely. One thing that is often overlooked is these companies' assistance programs. They absolutely make profits, and big ones. But most of them are actually pretty good about bending over to make sure that people who would benefit can get what they need. It's not a convenient process, but it's out there.
No, I am not in any way affiliated with any pharmaceutical company or product, though I have accepted lunch from them.
Posted on 3/29/17 at 8:35 pm to Hammond Tiger Fan
Weed actually helps.
Posted on 3/29/17 at 9:51 pm to Hammond Tiger Fan
Just slather peppermint essential oil on your forehead. The oils cure all.
Posted on 3/29/17 at 10:08 pm to Hopeful Doc
quote:
A step in the right direction? I hope so...
Cheaper insulin glargine is a step in the right direction but FWIW Basaglar costs a drop in the bucket less than Lantus.
My Medicare D patients with both COPD and diabetes are in the annual coverage gap by May, then their inhalers and DM injections ~ $1000 a month.
Branded meds used to be more reasonably priced. It's a long story.
Posted on 3/29/17 at 10:12 pm to NYNolaguy1
quote:
and will cost $65,000
The pharmaceutical sales rep whores are getting their panties wet in hopes of peddling this.
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