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Xyosted vs Testosterone Cyp

Posted on 3/30/26 at 3:39 pm
Posted by dangerousdon
Baton Rouge
Member since Jun 2008
650 posts
Posted on 3/30/26 at 3:39 pm
Any thoughts here? I’m going for my second lab test tomorrow. Doc wants to put me on 75 mg Xyosted weekly. I know little about it except that it is more expensive than test cyp. Supposedly it is a more steady dose (whatever that means, that’s what the nurse said). I expect insurance to say that I need to try something else first. But if they do say go ahead, looks like cost is about $150 a month but with a manufacturer card might be $25 a month. Looks like a three month supply of test c would be about $20 though. Appreciate any thoughts the wise ones here can give.

And for reference, my first tests were 334 total test and 6.1 free test. Total test was technically in the normal range. Free test was Low. Thanks again.
Posted by Arthur Bach
Member since Jul 2016
3155 posts
Posted on 3/30/26 at 3:52 pm to
Branded test? Don’t understand that.
Posted by LemmyLives
Texas
Member since Mar 2019
15209 posts
Posted on 3/30/26 at 5:55 pm to
It's probably the autoinjector, which you absolutely do not need. To get a more "steady" dose with test cyp, you just inject half the dose twice a week (M and Th for instance.)

Not sure how old you are, but 334 is not normal. It may be in the normal "range" but the normal range is from 264 to 916. You can have 1/3 of the free T of the guy standing next to you, and that's "normal?"

Posted by dangerousdon
Baton Rouge
Member since Jun 2008
650 posts
Posted on 3/30/26 at 6:45 pm to
I appreciate the response. I am definitely aware that my total is definitely not normal. The more I read on the Xyosted the more I learn that it’s not any better than anything else. I’m probably going to just see if I can go with Test C.
Posted by Gings5
Member since Jul 2016
11466 posts
Posted on 3/30/26 at 7:37 pm to
Been on both. I was doing cyp intramuscular once every two weeks but my body wasn’t absorbing it as consistently. Doctor swapped me to Xyosted. It’s the most convenient and easiest imo, but I had to swap back to cyp after I changed jobs and insurance.

I paid $10 per shot but had insanely good insurance. It was well worth it. Now I do cyp subq once a week. Much cheaper and still pretty easy. Regardless, subq is the way to go over IM.
Posted by LemmyLives
Texas
Member since Mar 2019
15209 posts
Posted on 3/30/26 at 9:11 pm to
Is your doc prescribing any aromatase inhibitor like anastrozole? If there isn't one in your program, you need to ask about it, and consider other doctors if one of them isn't included.
Posted by lsu777
Lake Charles
Member since Jan 2004
37612 posts
Posted on 3/31/26 at 7:34 am to
xyosted is testosterone enanthate in an auto injector.....it has a half life of 8 days vs 7 for cypionate


in other words, your doctor is making pay through the nose so he gets a kick back and the nurse is a typical nurse that thinks everyone else is stupid all while she doesnt understand half lifes. Being in an autoinjector doesnt change the ester weight to change the half life.

tell the nurse to go back to school and learn what esters are before just trying to dumb things down.
Posted by lsu777
Lake Charles
Member since Jan 2004
37612 posts
Posted on 3/31/26 at 7:35 am to
quote:

Is your doc prescribing any aromatase inhibitor like anastrozole? If there isn't one in your program, you need to ask about it, and consider other doctors if one of them isn't included.


why? you should never take an AI unless you are symptomatic. 99% of people on TRT do not need an AI.
Posted by Shepherd88
Member since Dec 2013
4925 posts
Posted on 3/31/26 at 7:50 am to
Yea that AI can frick your system up if you don’t need it. I ditched it a long time ago
Posted by Arthur Bach
Member since Jul 2016
3155 posts
Posted on 3/31/26 at 9:51 am to
quote:

in other words, your doctor is making pay through the nose so he gets a kick back


Doctors are not getting kickbacks from prescribing a branded drug. This is an ignorant and false claim.
Posted by lsu777
Lake Charles
Member since Jan 2004
37612 posts
Posted on 3/31/26 at 10:08 am to
quote:

Doctors are not getting kickbacks from prescribing a branded drug. This is an ignorant and false claim.


ok then explain to me like im 5 why they would prescribe a branded drug for 1 extra day of half life and that is also available as a generic?

so its either they are dumb or getting a kick back. there is no other possible scenario.

so which is it? incompetence or corruption?
Posted by Uncle JackD
Member since Nov 2007
59541 posts
Posted on 3/31/26 at 10:23 am to
at anyone who would pay for Test in a pen. It literally cost Pennies to make the compound. Now if insurance covers it, go right ahead. But mine would never. Hell I needed a prior authorization just to get my 10mL vial approved.
Posted by dangerousdon
Baton Rouge
Member since Jun 2008
650 posts
Posted on 3/31/26 at 2:09 pm to
Thanks for the replies guys. My insurance looks like they will pay for it if they approve it. But then it looks like it’s $150. There is a manufacturer card that would bring it down to $25 a month. But it also looks like they want you to try something else first. Test C looks like it’s $20 for a three month supply. I’m going to let the doc know I would prefer test C.
Posted by Uncle JackD
Member since Nov 2007
59541 posts
Posted on 3/31/26 at 2:29 pm to
That’s what I’d do. And it looks like that pen only goes up to 100mg, most need more than that to feel their best.
Posted by Arthur Bach
Member since Jul 2016
3155 posts
Posted on 3/31/26 at 2:46 pm to
quote:

ok then explain to me like im 5 why they would prescribe a branded drug for 1 extra day of half life and that is also available as a generic? so its either they are dumb or getting a kick back. there is no other possible scenario. so which is it? incompetence or corruption?


The product is marketed by Inizio Engage reps. Contract pharma reps. Kickbacks are illegal and that’s not the way pharma works. At all. They found some clinical trial and trying to make a buck on the data that says it’s in your system longer than test cyp. I personally take test cyp and wouldn’t take Xyosted.

But there’s clinical data somewhere that shows an advantage.

To answer your question-It’s there to make a buck for the company. Doctors do not get paid for writing prescriptions. That world does not exist anymore.


Posted by Gings5
Member since Jul 2016
11466 posts
Posted on 3/31/26 at 4:19 pm to
Guarantee the card doesn’t work like you think it does. Read the fine print again.
Posted by lsu777
Lake Charles
Member since Jan 2004
37612 posts
Posted on 4/1/26 at 7:27 am to
quote:

The product is marketed by Inizio Engage reps. Contract pharma reps. Kickbacks are illegal and that’s not the way pharma works. At all. They found some clinical trial and trying to make a buck on the data that says it’s in your system longer than test cyp. I personally take test cyp and wouldn’t take Xyosted.

But there’s clinical data somewhere that shows an advantage.

To answer your question-It’s there to make a buck for the company. Doctors do not get paid for writing prescriptions. That world does not exist anymore.




testosterone enanthate has been around for 50 years....we know there is no advantage so you answered the question.....the doctor is incompetent.
Posted by DarthRebel
Tier Five is Alive
Member since Feb 2013
25558 posts
Posted on 4/1/26 at 10:14 am to
My doctor tried to push Xyosted on me, was weird if there is no kick back scheme. My doctor is not the one who put me on T and my prescription is not through him. I do a local Men's Health clinic that is actually good at what they do.

He has known I have been on T since I started seeing him 5 years ago and then just randomly, hey you should try Xyosted. Has never cared about my T prescription, besides asking me annually if I was still on it.

Either he is sweet on the pharma rep or getting a slice of the pie.
Posted by Uncle JackD
Member since Nov 2007
59541 posts
Posted on 4/1/26 at 10:17 am to
So are are these reps telling the MD’s that Ethanate does more than cypionate or something? Still really weird that the pen maxes at 100mg. Not one guy that I know is on a dose that low.
This post was edited on 4/1/26 at 10:18 am
Posted by Arthur Bach
Member since Jul 2016
3155 posts
Posted on 4/1/26 at 11:02 am to
quote:

getting a slice of the pie.


This is not how pharma works, no matter how much yall want to believe it.
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