MIT researchers cleared 50% of Alzheimer’s plaques using 40 Hz sound waves

Loading Twitter/X Embed...
If tweet fails to load, click here.

quote:

---

- The post highlights MIT research on 40 Hz gamma entrainment using sound (and light) to reduce Alzheimer's amyloid plaques by up to 50% in mouse models via enhanced glymphatic clearance, as detailed in a 2024 Nature study by Tsai et al., though human trials show cognitive benefits mainly in late-onset cases.
- Accompanying image depicts fluorescently stained mouse brain tissue revealing amyloid-beta plaques (purple) and reduced burden post-stimulation, illustrating the non-invasive method's impact on brain waste removal without drugs or surgery.
- While promising for slowing decline in small human extension studies (e.g., 19-47% tau reduction in three participants), limitations include small sample sizes, variable efficacy by disease onset, and need for larger randomized trials, as noted in MIT's 2025 update.

---