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NAD craze is climbing. Can you test for those levels?

Posted on 6/7/25 at 7:55 am
Posted by Blutarsky
112th Congress
Member since Jan 2004
11543 posts
Posted on 6/7/25 at 7:55 am
Rho nutrition is all over social media with their liposomal delivery but it’s 100mg and 30 servings per bottle, which is $50-$60 each.

Injectable NAD is available but you need a script for it, or you order from a company like Get Blokes out of Columbia.

IV NAD therapy is the best delivery but the highest cost.

I use a brand that is a sublingual dissolving dosage that you take 2x per day for 300mg total.

Any other options?
This post was edited on 6/7/25 at 7:56 am
Posted by TigerReich
Ocean Springs, MS
Member since Dec 2024
219 posts
Posted on 6/7/25 at 10:23 am to
I take NAC and NAD
Posted by HVAU
Up over here
Member since Sep 2010
5053 posts
Posted on 6/7/25 at 10:42 am to
quote:

I use a brand that is a sublingual dissolving dosage that you take 2x per day for 300mg total.


What brand, if you don’t mind sharing? What are the effects that you’ve noticed?
Posted by Blutarsky
112th Congress
Member since Jan 2004
11543 posts
Posted on 6/7/25 at 12:00 pm to
quote:

What brand, if you don’t mind sharing? What are the effects that you’ve noticed?




Manufactured by a friend’s compounding pharmacy on the North Shore.

I buy a case every 4 months. Several friends buy a bottle or two from me when they need it.

I’ve been taking it for at least 5 years. They worked on the delivery method for a while before releasing it.

I wish I could have levels tested to see where they are in relation to my age. Most people are surprised how old I am.
This post was edited on 6/7/25 at 12:01 pm
Posted by Tenfold
Member since Mar 2023
231 posts
Posted on 6/7/25 at 1:15 pm to
I take the Real NAD+ and honestly don’t see a big difference. It’s pricey and I continue to take it but not sure how long I will continue.
Posted by Blutarsky
112th Congress
Member since Jan 2004
11543 posts
Posted on 6/7/25 at 1:30 pm to
How much do you pay for it? I think the real test is after you stop taking it and how you feel.
This post was edited on 6/7/25 at 1:30 pm
Posted by SquatchDawg
Cohutta Wilderness
Member since Sep 2012
17076 posts
Posted on 6/7/25 at 2:24 pm to
I took one of these for a while and figured out that the problem with any longevity drug is you’ll spend a fortune and never know if it’s working until….uh…you don’t die?
Posted by Tenfold
Member since Mar 2023
231 posts
Posted on 6/7/25 at 5:53 pm to
It was over $50 per container. Didn’t feel much different.
Posted by The Cow Goes Moo Moo
Bucktown
Member since Nov 2012
3713 posts
Posted on 6/9/25 at 10:27 am to
quote:

IV NAD therapy


I did this and found it to be a complete waste of money.
Posted by deathvalleytiger10
Member since Sep 2009
8361 posts
Posted on 6/10/25 at 2:39 pm to
What scientific research influenced you and persuaded you to begin taking NAD?
Posted by m2pro
Member since Nov 2008
29263 posts
Posted on 6/11/25 at 2:03 pm to
my bjj instructor guy does this in shot form. says it is night and day for him on his recovery speeds, and he can "feel" it in his system for days after he takes a shot of it. can't recall if he takes it once weekly or what.
Posted by Blutarsky
112th Congress
Member since Jan 2004
11543 posts
Posted on 6/11/25 at 6:41 pm to
I read a study in mice given NAD.

5 year old adult male mice taking NAD for a period of time and compared autopsies on them compared to 6 month old mice.

Cellular data showed them identical in every way. No aging shown in the adults.
This post was edited on 6/11/25 at 6:43 pm
Posted by pressurized
Member since Aug 2013
595 posts
Posted on 6/12/25 at 12:31 pm to
I researched it after hearing about it on a podcast. ChatGPT told me NAD was not very bioavailable other than IV. NMNH is a precursor to NAD (similar to NAC -> glutathione, which I'm a big fan of), and seems to be more bioavailable than NAD and has flooded the NAD market on Amazon, but there isn't enough research on it, according to AI. I don't have the time to dig into it myself, but does seem to be the new health influencer craze.
Posted by plaric
Pike Road, Alabama
Member since Jun 2011
2259 posts
Posted on 6/12/25 at 2:37 pm to
I am so confused. Da hell is NAD?
Posted by pressurized
Member since Aug 2013
595 posts
Posted on 6/12/25 at 4:03 pm to
Per ChatGPT (I have not checked the sources):

quote:

The Basics:

NAD+ (nicotinamide adenine dinucleotide) is critical for mitochondrial function, energy production, and DNA repair. Think of it as cellular fuel for cleanup and longevity processes (like sirtuin activation).

With age, NAD+ levels tank. Supplements aim to raise it.
quote:

Pros & Cons:

Compound Pros Cons

NAD+ Direct delivery Poor oral bioavailability
NMN Well-studied, effective Regulatory grey area (FDA cracked down on it as a “drug”)
NR Clean supply chain, patented, GRAS status May be less effective in muscle/brain
NMNH Promising speed & redox benefits Little to no human research, redox concerns

Final Skeptical Thought:

Boosting NAD+ indiscriminately is not a silver bullet. If the mitochondria are damaged or overloaded (e.g., by toxins, chronic stress, or poor sleep), you're just throwing more workers into a broken factory.




I'm holding off on it until more research, but following this thread.
Posted by SquatchDawg
Cohutta Wilderness
Member since Sep 2012
17076 posts
Posted on 6/13/25 at 10:13 am to
I took the Tru Niagen a while back which was expensive…however now it looks like NMN is the way to go and you can get that and reservatrol pretty reasonably from Bulk Supplements. I may give that a go and see if I notice anything.

It appears that there are questions of absorption with NAD+ whereas NMN is a precursor to NAD and is more easily absorbed. NMN has been shown to increase NAD levels in blood and interesting results in mice which is about all you can hope for at this stage of study.
This post was edited on 6/13/25 at 10:19 am
Posted by Blutarsky
112th Congress
Member since Jan 2004
11543 posts
Posted on 6/13/25 at 10:22 am to
Does anyone offer a blood test to check NAD levels?
This post was edited on 6/13/25 at 10:23 am
Posted by SquatchDawg
Cohutta Wilderness
Member since Sep 2012
17076 posts
Posted on 6/13/25 at 10:29 am to
Not that I’m aware. As I mentioned above and got downvoted, it’s one of those things that’s hard to quantify the value of taking as the goal is to prolong your life and improve cell function.

I started paying attention to it after David Sinclair did the JRE.

ETA: you can get 200 NMN servings at 500mg from Bulk Supplenets for $26 which is pretty good.
This post was edited on 6/13/25 at 10:37 am
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