Could you put a 13 lb. Brisket in the smoker at 180 and leave it overnight?

You need to be able to reach an internal temperature of 140F in less than four hours. At 180F your brisket won’t be very tender. You need an internal temp in the low 200s for that.

I’ve never cooked one that low. I wouldn’t recommend it but that doesn’t mean it won’t work. Try it and let us know.

A good rule of thumb is 1 hour per pound at 250. So at 250, you’ll figure you’ll need a 13 hour cook.

Assuming you’re using a pellet or electric smoker to keep the temp constant overnight? If so, put it on at 11 pm. It should be ready around noon the next day and let it sit warm in a cooler until 5:00. Of course, if its a stick burner, then you can’t keep the temp constant without waking up.

You are not going to render the fat at that low of a temp. Good luck and let us know how it turns tho.

I put mine on the Rec Teq @ 9 o'clock or so at 225, usually hit 160 right about 7 in the morning, time to wrap.

Just don’t put in on so early. Put it on at 9 or 10 at night.