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Gilead remdesivir study published in NEJM: two third of severe ill patients improved

Posted on 4/10/20 at 7:01 pm
Posted by Northwestern tiger
Long Island NY
Member since Oct 2005
23485 posts
Posted on 4/10/20 at 7:01 pm
quote:

In this cohort of patients hospitalized for severe Covid-19 who were treated with compassionate-use remdesivir, clinical improvement was observed in 36 of 53 patients (68%). Measurement of efficacy will require ongoing randomized, placebo-controlled trials of remdesivir therapy.

LINK
Posted by upgrayedd
Lifting at Tobin's house
Member since Mar 2013
134871 posts
Posted on 4/10/20 at 7:05 pm to
The media will call this irresponsible kook science
Posted by heatom2
At the plant, baw.
Member since Nov 2010
12812 posts
Posted on 4/10/20 at 7:06 pm to
This is a new drug, correct? I wonder how long it would take to mass produce.
Posted by baybeefeetz
Member since Sep 2009
31638 posts
Posted on 4/10/20 at 7:06 pm to
Oh will they?

Something tells me they won’t. Until Trump says anything about it.
This post was edited on 4/10/20 at 7:07 pm
Posted by kcon70
Houston, TX
Member since Sep 2016
2695 posts
Posted on 4/10/20 at 7:17 pm to
Been around since Ebola.
Posted by oilattorney4lsu
Baton Rouge
Member since Jul 2009
2068 posts
Posted on 4/10/20 at 7:20 pm to
quote:

two third of severe ill patients improved


Where did you get the “severe” part? Are all hospitalized patients in the study considered severe? Or were some moderate but being monitored in the hospital?

I’m not trying to argue with you just trying to analyze this article. Were 2/3rds going to recover with no medical treatment anyway? I wish it was a higher percentage than 68%.

Posted by Northwestern tiger
Long Island NY
Member since Oct 2005
23485 posts
Posted on 4/10/20 at 7:22 pm to
quote:

Where did you get the “severe” part?


It’s in the title of the manuscript
quote:

Compassionate Use of Remdesivir for Patients with Severe Covid-19

Posted by Northwestern tiger
Long Island NY
Member since Oct 2005
23485 posts
Posted on 4/10/20 at 7:22 pm to
Read the material and method section in more details
Posted by upgrayedd
Lifting at Tobin's house
Member since Mar 2013
134871 posts
Posted on 4/10/20 at 7:23 pm to
quote:

Something tells me they won’t. Until Trump says anything about it.

They'll find some tangential investment he has that's linked to the manufacturer and say Trump stands to profit
Posted by Northwestern tiger
Long Island NY
Member since Oct 2005
23485 posts
Posted on 4/10/20 at 7:24 pm to
quote:

The media will call this irresponsible kook science


NEJM is the top medical journal in the world. Impact factor is like 50
Posted by heatom2
At the plant, baw.
Member since Nov 2010
12812 posts
Posted on 4/10/20 at 7:25 pm to
quote:

Been around since Ebola.


Oh shite it's the Ebola antiviral. That's good news. Ready for some treatment options that work so I can get out of this fricking house.
Posted by Fun Bunch
New Orleans
Member since May 2008
116076 posts
Posted on 4/10/20 at 7:28 pm to
Depending on the severity of the patients that’s good news.
Posted by PickupAutist
Member since Sep 2018
3022 posts
Posted on 4/10/20 at 8:07 pm to
The media will praise this one because it is patented and gilead stands to gain a lot of money from it unlike HCQ.
Posted by ABearsFanNMS
Formerly of tLandmass now in Texas
Member since Oct 2014
17478 posts
Posted on 4/10/20 at 8:31 pm to
quote:

The media will praise this one because it is patented and gilead stands to gain a lot of money from it unlike HCQ.



Exactly what I was thinking.
Posted by AUstar
Member since Dec 2012
17052 posts
Posted on 4/10/20 at 8:33 pm to
quote:

Were 2/3rds going to recover with no medical treatment anyway?


The only way to answer that is to do randomized double blind trials, which this doesn't appear to be. But it is enough evidence to proceed with such trials.
Posted by Adam Banks
District 5
Member since Sep 2009
31950 posts
Posted on 4/10/20 at 8:55 pm to
Game changer.
Posted by Ace Midnight
Between sanity and madness
Member since Dec 2006
89583 posts
Posted on 4/10/20 at 9:02 pm to
quote:

remdesivir


This is the key late stage treatment.

The HCQ/Z-pak/Zinc cocktail needs to be earlier - when the case gets serious, but before desat levels get into ventilator areas.
Posted by Ace Midnight
Between sanity and madness
Member since Dec 2006
89583 posts
Posted on 4/10/20 at 9:03 pm to
quote:

The only way to answer that is to do randomized double blind trials


These aren't even ethical with a life-threatening illness, IMHO.
Posted by Ace Midnight
Between sanity and madness
Member since Dec 2006
89583 posts
Posted on 4/10/20 at 9:04 pm to
quote:

They'll find some tangential investment he has that's linked to the manufacturer and say Trump stands to profit




The position they're taking that is, if Trump stands to benefit from it politically or make a single red cent (he's a billionaire, after all), then the MSM would rather everyone die instead.

I'm not exaggerating.
Posted by Jimmy2shoes
The South
Member since Mar 2014
11004 posts
Posted on 4/10/20 at 9:37 pm to
gild
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