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Posted on 11/15/23 at 2:31 pm to BeepNode
I don’t need some test to tell me I have the motherfricker gene. Just look at my wallet.
Posted on 11/15/23 at 2:50 pm to Scruffy
quote:
Parents make it worse because they demand something be done and refuse to accept that there is nothing wrong with their child and they simply need to fricking parent
I demanded the opposite, but was told repeatedly I wasn’t helping to realize my child’s potential by making her focus on one thing at a time using stimulants. Ridiculous. Her private catholic school wanted little robots with straight As. I refused and we skated through 8th with a b-c average and a happy kid. Now she’s thriving in a rigorous catholic high school. Oddly making mostly As.
Posted on 11/15/23 at 3:11 pm to BeepNode
quote:
For the uninitiated, the gene is believed by some conspiracy theorists to inhibit the body's ability to process folic acid, which is artificially added to our food supply.
If true, those people are idiots. Firstly, its not to process folic acid as direct use. Its to convert folic acid if the body decides it has enough of that essential amino acid, and convert it to another one. And it doesn't inhibit anything. Its design is to be a part of the process to successfully methylate folate to methionine.
There are defective VERSIONS of the gene that do not work well, and cause issues. But if you go up to a medical professional asking if you had the MTHFR gene, you just flagged yourself as too ignorant to even understand the results if given them.
On a side note, its typically only added to flours. (Its part of what is meant by enriched flour), and only so because it was quite easy to have folate missing in the diet, at the consequence of pretty bad birth defects. So they started to add some essential amino acids to bread. BTW, this was close to 100 years ago, so not like something new we just hadn't seen the effects from yet.
quote:
This inability to process folic acid down to its methylated form causes mental and cardiovascular problems, the conspiracy theorists claim.
They haven't been able to reproduce any sort of trend or connection to it as yet.
But be aware "mental issues" aren't the typical dog whistles of the overmedicated anxiety and ADHD diagnosis.
Its shite like dementia, seizures, and loss of motor control.
EDIT:
The "official" reason why its not recommended to test
LINK
This post was edited on 11/15/23 at 3:21 pm
Posted on 11/15/23 at 3:16 pm to BeepNode
Our youngest has the mutherfricker gene. You have to supplement with derived B vitamins…..
Posted on 11/15/23 at 3:21 pm to BeepNode
quote:
elieved by some conspiracy theorists to inhibit the body's ability to process folic acid
So doctors and clinical researchers?
Posted on 11/15/23 at 7:00 pm to Volvagia
I see your 2013 article and raise you a 2021 article. The internet is always right
I only read the summary and lord knows where it came from. It does say that the expression of the symptoms vary widely based on a host of factors, which I agree with based on what I’ve seen within my own family. My husband and I each have a different mutation regarding methylation & I won’t cite the type (gold jacket, green jacket, who gaf) each kid inherited both mutations. All of us have some “symptoms” of reduced methylation, but none of us have the same symptoms or severity. Same goes to how we responded to adding the methylated b vitamins and other supplements. I can tell you that it improved two lives greatly enough that I’ll take my time to convince others that methylation defects are not to be disregarded. My son went from struggling to make 2/3 word phrases using echolalia to making actual coherent statements we could understand in two weeks, just by adding a methylated b vitamin. His progress continued after we received blood work and urine work and added different supplements and did chelation therapy because methylation defects sometimes hinder your ability to detox heavy metals. Please do not dismiss MTHFR, or the other methylation gene mutations.
I only read the summary and lord knows where it came from. It does say that the expression of the symptoms vary widely based on a host of factors, which I agree with based on what I’ve seen within my own family. My husband and I each have a different mutation regarding methylation & I won’t cite the type (gold jacket, green jacket, who gaf) each kid inherited both mutations. All of us have some “symptoms” of reduced methylation, but none of us have the same symptoms or severity. Same goes to how we responded to adding the methylated b vitamins and other supplements. I can tell you that it improved two lives greatly enough that I’ll take my time to convince others that methylation defects are not to be disregarded. My son went from struggling to make 2/3 word phrases using echolalia to making actual coherent statements we could understand in two weeks, just by adding a methylated b vitamin. His progress continued after we received blood work and urine work and added different supplements and did chelation therapy because methylation defects sometimes hinder your ability to detox heavy metals. Please do not dismiss MTHFR, or the other methylation gene mutations.
Posted on 11/15/23 at 8:57 pm to el Gaucho
quote:
Russians also dominate in the lower body portion of powerlifting competitions because they squat instead of using chairs
That’s the first funny thing I’ve ever thought you said and I had to be high to think so.
Posted on 11/15/23 at 9:04 pm to Saint Alfonzo
Which one is it?
Posted on 11/15/23 at 9:32 pm to domesticengineer
quote:
To repair that issue, you take methylfolate (in a methylated b-complex) instead of folate and avoid folic acid.
This makes no sense.
quote:
If you simply diagnose a genetic mutation and tell the patient to begin supplementing with methylated B vitamins and some other precursor vitamins for proper neurotransmitter pathway functions that would take lots of $$$$$$ out of the system.
There’s money in folic acid supplements?
You guys need to be more circumspect about these wackos, whose theories do not hold up to any scrutiny at all.
quote:
I think the reason MTHFR isn’t taken seriously yet is because it doesn’t affect everyone exactly the same way… and because it wouldn’t turn a profit for pharma
Lol
Posted on 11/15/23 at 10:43 pm to domesticengineer
The saddest thing is that 1) single studies rarely supplant meta analysis, which was the link I referenced.
Second:
Please don’t hurt yourself trying to read primary literature, if your reading comprehension is that poor. I flat out said they existed. I flat out said they had major problems. And what you linked doesn’t contradict ANYTHING I said. What, you thought I wouldn’t read it? Or did you just skim it thinking it supported you.
I just attacked the low education, conspiracy theory buzz words. I attacked calling generalized MTHFR as a problem, which it isn’t.
Second:
quote:
Please do not dismiss MTHFR, or the other methylation gene mutations.
Please don’t hurt yourself trying to read primary literature, if your reading comprehension is that poor. I flat out said they existed. I flat out said they had major problems. And what you linked doesn’t contradict ANYTHING I said. What, you thought I wouldn’t read it? Or did you just skim it thinking it supported you.
I just attacked the low education, conspiracy theory buzz words. I attacked calling generalized MTHFR as a problem, which it isn’t.
This post was edited on 11/16/23 at 1:37 am
Posted on 11/15/23 at 10:52 pm to crazy4lsu
quote:
There’s money in folic acid supplements?
You guys need to be more circumspect about these wackos, whose theories do not hold up to any scrutiny at all.
The funny thing is that the toxic effects aren’t from folate at all. It’s 100% from being able to remove homocysteine, an intermediate toxic compound in the process of making cysteine, an essential amino acid.
The pathway.
Her fam is taking methylated precursors and b12 to bypass MTHFR rate limiting step, which is fine and scientifically backed, but then throws in voodoo for her conspiracy theory.
Posted on 11/16/23 at 5:36 am to Volvagia
Of course I didn’t read the whole thing. The link was pasted as a “gotcha” joke. You can find anything on the internet to support any side of any argument.
My post was only meant to reach the open minded folks who want to listen to first hand accounts instead of those just looking for an argument while browsing the internet cherry picking mud to sling.
My post was only meant to reach the open minded folks who want to listen to first hand accounts instead of those just looking for an argument while browsing the internet cherry picking mud to sling.
Posted on 11/16/23 at 6:07 am to domesticengineer
quote:
Gary Brecka explained methylation the best that I’ve heard so far. Methylation defects can lead to MANY issues that are currently fixed by pharmaceuticals. The inability to properly methylate B vitamins can also make it very difficult or somewhat difficult to carry a pregnancy to term depending on the type of mutation you have. To repair that issue, you take methylfolate (in a methylated b-complex) instead of folate and avoid folic acid. If you simply diagnose a genetic mutation and tell the patient to begin supplementing with methylated B vitamins and some other precursor vitamins for proper neurotransmitter pathway functions that would take lots of $$$$$$ out of the system. I think the reason MTHFR isn’t taken seriously yet is because it doesn’t affect everyone exactly the same way… and because it wouldn’t turn a profit for pharma.
Exactly. It’s more profitable for us to have the health problems than to fix the problems.
My daughter was tested in her doctor’s office with other bloodwork. She has one mutation. She’s on methylated vitamins and she tries not to eat enriched foods. She uses about 90% non-toxic products. We can see a difference in how she feels.
There’s a podcast called To Health with That and she did a whole series on MTHFR. I need to watch the one y’all are referencing. She said you don’t really have to test, especially if you have some of the symptoms and physical signs of having it. Just take the methylated vitamins, don’t eat enriched foods and try to have fewer toxins in your life.
I read that people of European descent are most affected.
This post was edited on 11/16/23 at 6:08 am
Posted on 11/16/23 at 6:41 am to BeepNode
I started this thread last month that is similar
LINK
Since then, we have found out my wife is pregnant. Because of her having the MTHFR gene mutation (which she had been tested for years ago) she had to get special prenatal vitamins without folic acid. I thought this was weird and caused me to go down the rabbit hole on folic acid. Meanwhile the Gary Brecka Rogan podcast comes out and then everything makes sense.
I’ve went out and bought non enriched folic acid free flour, which was sadly rather difficult, and bought a cuisine art pasta roller attachment for my kitchen aid and have been making pasta noodles from scratch, along with cooking vast majority of our other meals at home. She is doing tremendously better and I think this was the key.
Reading up on the implementation of folic acid into the food supply (which only started in the 90s), it seems that it was something done with good intentions to help with development of babies with mothers who don’t know any better or how to take care of themselves. However, at a minimum it seems to have been short sighted without regard for potential consequences, and of course these pharmaceutical companies who make the folic acid get rich in the process.
Hopefully a backlash of sort will begin to build around this.
LINK
Since then, we have found out my wife is pregnant. Because of her having the MTHFR gene mutation (which she had been tested for years ago) she had to get special prenatal vitamins without folic acid. I thought this was weird and caused me to go down the rabbit hole on folic acid. Meanwhile the Gary Brecka Rogan podcast comes out and then everything makes sense.
I’ve went out and bought non enriched folic acid free flour, which was sadly rather difficult, and bought a cuisine art pasta roller attachment for my kitchen aid and have been making pasta noodles from scratch, along with cooking vast majority of our other meals at home. She is doing tremendously better and I think this was the key.
Reading up on the implementation of folic acid into the food supply (which only started in the 90s), it seems that it was something done with good intentions to help with development of babies with mothers who don’t know any better or how to take care of themselves. However, at a minimum it seems to have been short sighted without regard for potential consequences, and of course these pharmaceutical companies who make the folic acid get rich in the process.
Hopefully a backlash of sort will begin to build around this.
This post was edited on 11/16/23 at 6:56 am
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