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Started By
Message
Scientists have developed an LSD-based anxiolytic.
Posted on 10/6/22 at 7:02 am
Posted on 10/6/22 at 7:02 am
NPR
Nature
Nature
quote:
Now, scientists report in the journal Nature that they have created drugs based on LSD that seem to relieve anxiety and depression – in mice – without inducing the usual hallucinations.
"We found our compounds had essentially the same antidepressant activity as psychedelic drugs," says Dr. Bryan Roth, an author of the study and a professor of pharmacology at UNC Chapel Hill School of Medicine. But, he says, "they had no psychedelic drug-like actions at all."
The discovery could eventually lead to medications for depression and anxiety that work better, work faster, have fewer side effects, and last longer.
14
Posted on 10/6/22 at 7:07 am to UndercoverBryologist
It will only take 20 years to get FDA approval.
Posted on 10/6/22 at 7:07 am to UndercoverBryologist
I’m a big fan of psychedelics for mental health. It’s crazy how many trials are going on right now
I heard a doctor on a podcast a while back predict that they will replace SSRIs for anxiety, PTSD and depression by 2030
I heard a doctor on a podcast a while back predict that they will replace SSRIs for anxiety, PTSD and depression by 2030
Posted on 10/6/22 at 7:08 am to jdd48
quote:
It will only take 20 years to get FDA approval.
MDMA is in phase 3 for PTSD. Most predict it will be approved in the next year
Posted on 10/6/22 at 7:08 am to jdd48
Call it a vaccine and the fda will approve it next week
Posted on 10/6/22 at 7:10 am to dallastiger55
quote:
MDMA is in phase 3 for PTSD. Most predict it will be approved in the next year
can't wait
Posted on 10/6/22 at 7:35 am to UndercoverBryologist
quote:
to relieve anxiety and depression – in mice
How the frick do they know if a mouse is depressed?
Posted on 10/6/22 at 7:41 am to UndercoverBryologist
quote:
that seem to relieve anxiety and depression – in mice
I’m all for modern medicine, I’ve been a benefactor in recent years.
But how can they can tell if a mouse has anxiety or depression.
Posted on 10/6/22 at 7:41 am to TheRouxGuru
Author Michael Pollan has a series on Netflix called How to Change Your Mind
He’s in his 70s and went around to learn more about psychedelics. They are doing trials with elderly nursing home patients in hospice and they were interviewed saying how their outlook on life has changed and they are no longer afraid of death.
It’s really fascinating. They all said they are able to go back to seeing themselves being born and reliving memories and being at peace. They all said when they came out of the trip it was like they were a new person and weren’t afraid. Pretty cool
He’s in his 70s and went around to learn more about psychedelics. They are doing trials with elderly nursing home patients in hospice and they were interviewed saying how their outlook on life has changed and they are no longer afraid of death.
It’s really fascinating. They all said they are able to go back to seeing themselves being born and reliving memories and being at peace. They all said when they came out of the trip it was like they were a new person and weren’t afraid. Pretty cool
This post was edited on 10/6/22 at 7:43 am
Posted on 10/6/22 at 8:04 am to Nicky Parrish
quote:
But how can they can tell if a mouse has anxiety or depression.
Starvation, heat the cage pan, place cage in room with a cat. Seriously.
Posted on 10/6/22 at 8:38 am to UndercoverBryologist
quote:
without inducing the usual hallucinations.
So they removed the best part
Posted on 10/6/22 at 8:47 am to TheRouxGuru
quote:
How the frick do they know if a mouse is depressed?
Posted on 10/6/22 at 9:02 am to UndercoverBryologist
One of the mice from the study. I’m a little leery about what they profess this new drug can do.
This post was edited on 10/6/22 at 9:25 am
Posted on 10/6/22 at 9:07 am to UndercoverBryologist
Psychedelics are the future of psychiatry.
Approval won't take as long as you might think.
Especially after that big review lampooning SSRIs. That Avenue of profit is being shut down.
They'll need another. It helps that it is incredibly lucrative. See: Ketamine clinics.
Approval won't take as long as you might think.
Especially after that big review lampooning SSRIs. That Avenue of profit is being shut down.
They'll need another. It helps that it is incredibly lucrative. See: Ketamine clinics.
Posted on 10/6/22 at 9:10 am to UndercoverBryologist
quote:
they had no psychedelic drug-like actions at all."
that sucks
Posted on 10/6/22 at 9:15 am to UndercoverBryologist
Just a matter of time.
Posted on 10/6/22 at 9:25 am to UndercoverBryologist
I didn’t know that mice got depressed.
I guess eating cheese off the floor can be depressing
Anxiety I can understand - Fearing for your life every time you see some cheese could induce anxiety
And then there the sad fact that they’re mice…
I guess dropping acid makes sense
I guess
I guess eating cheese off the floor can be depressing
Anxiety I can understand - Fearing for your life every time you see some cheese could induce anxiety
And then there the sad fact that they’re mice…
I guess dropping acid makes sense
I guess
Posted on 10/6/22 at 9:26 am to UndercoverBryologist
People will try to find any excuse they can to justify getting high.
Posted on 10/6/22 at 9:29 am to UndercoverBryologist
quote:
they had no psychedelic drug-like actions at all
A really hard trip where the ego dissolves into space-time is what helped me get over some things. Maybe not everyone needs to go that deep, but it sure did the trick for me.
Posted on 10/6/22 at 9:30 am to UndercoverBryologist
quote:
without inducing the usual hallucinations.
To me that's like drinking O'Doul's.
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