re: New vape pen features DMT as main ingredient

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Roger, you can easily distill some crystals from plant matter, FYI. Not hard to find instructions.

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Drugs and the Meaning of Life

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Joe Rogan Experience #477 - Dennis McKenna & Josh Wickerham

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Dennis McKenna is an ethnopharmacologist, author, and brother to well-known psychedelics proponent Terence McKenna. Josh Wickerham is the chief advisor to the ESC, Ethnobotanical Stewardship Council.

LINK

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Terence Kemp McKenna (November 16, 1946 – April 3, 2000) was an American ethnobotanist, mystic, psychonaut, lecturer, author, and an advocate for the responsible use of naturally occurring psychedelic plants. He spoke and wrote about a variety of subjects, including psychedelic drugs, plant-based entheogens, shamanism, metaphysics, alchemy, language, philosophy, culture, technology, environmentalism, and the theoretical origins of human consciousness. He was called the "Timothy Leary of the '90s",[1][2] "one of the leading authorities on the ontological foundations of shamanism",[3] and the "intellectual voice of rave culture".[4]

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In his book Food of the Gods, McKenna proposed that the transformation from humans' early ancestors Homo erectus to the species Homo sapiens mainly had to do with the addition of the mushroom Psilocybe cubensis in its diet,[25][70][71] an event that according to his theory took place in about 100,000 BCE (this is when he believed that the species diverged from the Homo genus).[21][72] McKenna based his theory on the main effects, or alleged effects, produced by the mushroom[3] while citing studies by Roland Fischer et al. from the late 1960s to early 1970s.[73][74]

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Rick Strassman (born February 8, 1952 in Los Angeles, California) is a medical doctor specialized in psychiatry with a fellowship in clinical psychopharmacology research. He has held a fellowship in clinical psychopharmacology research at the University of California San Diego and was Professor of Psychiatry for eleven years at the University of New Mexico. [1] After twenty years of intermission, Strassman was the first person in the United States to undertake human research with psychedelic, hallucinogenic, or entheogenic substances with his research on N,N-dimethyltryptamine. He is also the author of the well known book "DMT: Spirit Molecule" which summarizes his academic research into DMT and includes his own reflections and conclusions based on this research.

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Psychedelic drug research[edit]
Strassman's studies, taking place between 1990 and 1995 in the General Clinical Research Center of the University of New Mexico Hospital, aimed to investigate the effects of N,N-dimethyltryptamine (DMT), a powerful psychedelic drug, that is found in hundreds of plants and every mammal that has been studied. DMT is made primarily in mammalian lung tissue, and is related to human neurotransmitter serotonin and the pineal hormone melatonin.

Strassman refers to DMT as the "spirit molecule" because its effects include many features of religious experience, such as visions, voices, disembodied consciousness, powerful emotions, novel insights, and feelings of overwhelming significance. During the project's five years, he administered approximately 400 doses of DMT to nearly five dozen human volunteers.[6][7] Strassman was the first to legally administer psychedelics to people in the United States in 20 years, and his research has widely been regarded as kicking off the "psychedelic renaissance", in which many psychedelic compounds have begun again to be scientifically studied since the early 70s.[8][9]

Strassman characterized biological and psychological effects in his first set of dose-response studies, effects consistent with activation of central and/or peripheral serotonin receptors.[10] His team published a companion article describing psychological effects and preliminary results of a new rating scale, the Hallucinogen Rating Scale, or HRS.[11] The HRS has seen wide acceptance throughout the international research community as a sensitive and specific instrument for measuring psychological effects of a wide variety of psychoactive substances, with over 45 articles documenting its use as of mid-2015. A follow-up DMT study demonstrated lack of tolerance to the psychological effects of repeated closely spaced doses of DMT, making DMT unique among classical psychedelics.[12]

More than half of Strassman’s volunteers reported profound encounters/interaction with non-human beings while in a dissociated state. Dr. Strassman has conjectured that when a person is approaching death or possibly when in a dream state, the body releases DMT in a relatively large amount, mediating some of the imagery reported by survivors of near-death experiences. However, there are no data correlating endogenous DMT activity to non-drug-related altered states of consciousness.[13] He also has theorized that the pineal gland may form DMT under certain conditions, and in 2013 researchers first reported DMT in the pineal gland microdialysate of rodents.[14]

He has detailed his research in his book DMT: The Spirit Molecule; and he co-produced a documentary film by the same name DMT: The Spirit Molecule, based on this book.[15] Dr. Strassman has also conducted similar research using psilocybin, a psychedelic alkaloid found in hallucinogenic mushrooms. In unpublished studies, he administered doses of up to 1.1 mg/kg, nearly three times the doses considered "psychedelic" in contemporary clinical research with this compound.[16] He also had permission to begin an LSD study, but he did not begin by the time he finished his DMT study.

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I would consider using them again them in order to expand the depth of my conquest for spirituality, not to get high.

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Has anyone here smoked salvia? That shite was wild

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So what is the difference between DMT and LSD?

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really made me appreciate the feeling of being back on earth and in the real world.

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Your brain hallucinates your conscious reality

| Anil Seth 5,049,168 views 103K 3.9K Share Save Report TED 13,570,072 subscribers SUBSCRIBE
Published on Jul 18, 2017

Right now, billions of neurons in your brain are working together to generate a conscious experience -- and not just any conscious experience, your experience of the world around you and of yourself within it. How does this happen? According to neuroscientist Anil Seth, we're all hallucinating all the time; when we agree about our hallucinations, we call it "reality." Join Seth for a delightfully disorienting talk that may leave you questioning the very nature of your existence.

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lmao. not even what it about

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