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re: Lipitor side effects

Posted on 8/8/18 at 6:57 pm to
Posted by Browncoatrebel
Member since Nov 2017
1107 posts
Posted on 8/8/18 at 6:57 pm to
Better than a stroke or coronary artery disease
Posted by treyk89
Member since Oct 2003
2264 posts
Posted on 8/8/18 at 6:57 pm to
And for the record my Dr has waited several years before getting me on meds. We tried diet, niacin, fish oils and etc

My dad had quadruple bypass in his 50’s, my grand father had same thing in his 60’s

Posted by Roger Klarvin
DFW
Member since Nov 2012
46505 posts
Posted on 8/8/18 at 6:58 pm to
quote:


Yeah my total cholesterol is 292. Triglycerides 242. LDL 204


Statistically it is likely you simply have a predisposition to having lots of small, dense LDL particles. Like I said, it is very uncommon that a person (especially one who exercises and eats as least an ok diet) with an LDL > 190 has a predominance of the safer large LDL particles. At LDL levels as high as yours, the data is VERY clear: It is a strong independent risk factor for vascular disease later in life.

But going out of pocket for a LDL profile at a private lab might be worthwhile to further stratify your risk if you can afford it.
Posted by Roger Klarvin
DFW
Member since Nov 2012
46505 posts
Posted on 8/8/18 at 7:03 pm to
quote:

My dad had quadruple bypass in his 50’s, my grand father had same thing in his 60’s


That's a pretty strong family history. If they needed bypass surgery at that age, it is a virtual certainty they had at least moderate CAD in their 40s.

I'll be honest: If I was your doctor, with those cholesterol levels and that family history, I'd encourage frequent aerobic exercise with 2-3 days of resistance training a week, a vegan or nearly vegan diet and a moderate intensity statin. Niacin certainly won't hurt if you can tolerate it, though the mortality benefit is questionable at best thus far.

You're set up for early coronary disease without taking steps now to prevent it.
Posted by Rust Cohle
Baton rouge
Member since Mar 2014
1937 posts
Posted on 8/8/18 at 7:03 pm to
Thanks Roger! What is it about red meat that’s so bad?
Posted by treyk89
Member since Oct 2003
2264 posts
Posted on 8/8/18 at 7:05 pm to
quote:

But going out of pocket for a LDL profile at a private lab might be worthwhile to further stratify your risk if you can afford it.


I had one done at LabCorp

It was 2895
Posted by Roger Klarvin
DFW
Member since Nov 2012
46505 posts
Posted on 8/8/18 at 7:08 pm to
quote:

Yes I had he LDL-P done too. It was 2895


Not gonna lie, that's alarming. Levels that high generally indicate an underlying genetic predisposition as even the most unhealthy diabetic usually top out around 2500 or so.

Any physician worth their salt, cardiologist or otherwise, should have you on a statin. IMO your doctor is doing exactly what he should be doing.
Posted by treyk89
Member since Oct 2003
2264 posts
Posted on 8/8/18 at 7:11 pm to
Thank you.

My dad has diabetes as well. And so did my aunt.

My insulin resistance level was elevated but blood sugar was normal. All things considered that’s why he’s putting me on meds. 40mg Lipitor
Posted by Roger Klarvin
DFW
Member since Nov 2012
46505 posts
Posted on 8/8/18 at 7:19 pm to
quote:

What is it about red meat that’s so bad?


A big component is the treatments we given our livestock to prevent disease and improve yield. Cattle bred for meat specifically are drowned in chemical modifiers prior to slaughter.

Red meat tends to promote constipation and increase bile secretion which is a key component of the popular "leaky gut" hypothesis which states that bowel disease/damage and gut stasis leads to microbial translocation from the guy, immune response to that bacteria and subsequent chronic inflammation.

Saturated fats are inherently pro-inflammatory.

Red meat has the strongest correlation with elevated high-sensitivity CRP of any single genre of food

It leads to higher levels of arachidonic acid, another pro-inflammatory mediator.

It promotes insulin resistance (to the same degree brown rice does surprisingly)

It leads to a metabolite called trimethylamine-N-oxide which is an oxidizing agent

Etc.
Posted by shamrock
Baton Rouge
Member since Sep 2015
3620 posts
Posted on 8/8/18 at 8:49 pm to
Damn Roger, as a fellow doc, GI, that was some solid advice and excellent explanation.. board level stuff, good on ya, and I’m on Lipitor too
Posted by Junky
Louisiana
Member since Oct 2005
8357 posts
Posted on 8/8/18 at 8:56 pm to
quote:

Anyone >35-40 with diabetes should be on a statin regardless of cholesterol numbers


Good god man, you're a fricking pill pusher. Thank god you're not my fricking doctor. There is absolutely no reason to say shite like this. No fricking pill will solve life's issues.

How about lifestyle/diet changes? those are just as effective to getting cholesterol numbers back in line AND it doesn't cost shite.
Posted by shamrock
Baton Rouge
Member since Sep 2015
3620 posts
Posted on 8/8/18 at 9:00 pm to
I can tell you aren’t a doctor. Please takeover my clinic tomorrow and discuss lifestyle changes for the tenth time with every overweight patient. Prescribing meds aren’t the first thing good docs do and docs aren’t getting kickbacks for prescribing meds.
Posted by LSUTiger1026
Member since Sep 2017
146 posts
Posted on 8/8/18 at 9:09 pm to
What strict diet did you try? Have you considered cutting grains and eating mostly fruits, vegetables, nuts, grass fed beef, organic poultry, pastures pork, and wild caught fatty fish? Look up Whole 30. Your triglyceride levels tell me that your processed and refined carbohydrates are high even if calories were restricted. Try eating only within an 8-12 hour window. When you do eat, make your plate primarily vegetables with a palm sized portion of meat on the side. If you decide to strength train, then you can increase protein intake. Try to get six to nine servings a day of veggies. Don’t worry about calorie counting. Eat only real whole food and shop around the perimeter of the grocery store. It may not be easy at first, but it becomes natural and in time, you will enjoy it more than junk food as it will make you feel great. Let me know if I can help or provide more information. Good luck.
Posted by Junky
Louisiana
Member since Oct 2005
8357 posts
Posted on 8/8/18 at 9:15 pm to
quote:

A big component is the treatments we given our livestock to prevent disease and improve yield. Cattle bred for meat specifically are drowned in chemical modifiers prior to slaughter.


There are cattle withdrawal times for different chemicals used put out by the companies that make them. Withdrawal times are different for corresponding drugs.
Posted by LSUTiger1026
Member since Sep 2017
146 posts
Posted on 8/8/18 at 9:17 pm to
First off, thanks for all the information in this thread, I enjoyed the back and forth between the two camps. But where are you sourcing the information from this post? Are you confident enough to say that grass fed organically raised beef is pro inflammatory? I assume you are sourcing these statements from various studies. Within those, did they feed the subjects saturated fats in combination with a high carbohydrate diet? Or were refined carbs and added sugar removed? I agree with you that conventionally raised beef is terrible, but that is not to say that all red meat is as well.
Posted by Junky
Louisiana
Member since Oct 2005
8357 posts
Posted on 8/8/18 at 9:18 pm to
quote:

I can tell you aren’t a doctor. Please takeover my clinic tomorrow and discuss lifestyle changes for the tenth time with every overweight patient. Prescribing meds aren’t the first thing good docs do and docs aren’t getting kickbacks for prescribing meds.


Did what he said sound like that? No. He said every diabetic should be on a satin even if their numbers are good.

Oh, and btw - I wouldn't be so pissed if the entirety of medical authorities would get off their ego trips and realize that America is 17% obese with 30% of children obese because of their collectively horrible advice over the past 6 decades. Only weathermen could do worse and keep their jobs. It is an indictment of medical advice. Maybe there is something wrong with the advice, and not America. And this statement is coming from someone who lost 20lbs and cured his depression by doing everything completely opposite of what they recommend.
This post was edited on 8/8/18 at 9:37 pm
Posted by LSUTiger1026
Member since Sep 2017
146 posts
Posted on 8/8/18 at 9:35 pm to
I would like to second the docs advice to start strength training. It is the best way to fully deplete glycogen stores and will decrease insulin resistance. If you decide to lift in circuit fashion or with super, tri, or giant sets it could give you a cardio component within strength training itself.
Posted by Roger Klarvin
DFW
Member since Nov 2012
46505 posts
Posted on 8/8/18 at 9:40 pm to
quote:

Good god man, you're a fricking pill pusher. Thank god you're not my fricking doctor. There is absolutely no reason to say shite like this. No fricking pill will solve life's issues.


It's the standard of care. Not only is it the right thing to do based on all available evidence, you're fair game for a lawsuit if you don't follow guidelines and a patient has a bad outcome.

For people with a constant highly inflammatory state such as diabetes, the evidence shows the lower the better. Any available LDL and VLDL will be deposited in such patients.

And I'm not getting kickbacks for fricking Lipitor
This post was edited on 8/8/18 at 9:40 pm
Posted by Roger Klarvin
DFW
Member since Nov 2012
46505 posts
Posted on 8/8/18 at 9:44 pm to
Docs certainly haven't always given the best dietary advice, but the subsidizing of unhealthy shite has more to do with the obesity epidemic than anything else. We have the most unhealthy, addictive foods the cheapest and easiest to obtain.
Posted by FatMan
Louisiana
Member since Oct 2016
1762 posts
Posted on 8/8/18 at 9:49 pm to
Where do you practice and when did you get finished with school? I want to stay the f**k away from you. You are the idiot that believes what they learned and has never researched that learning independently. You are probably cheap, so just download pubmed and research non-epidemiological studies on CV risk. You are what's wrong with medicine in this world...

To take from Billy Madison, Amongst your rambling I have failed to pick up on anything that seems coherent. I award you 0 points and may God have mercy on your soul.
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