Baton Rouge Study on Time-Restricted Feeding (s/k/a "intermittent fasting")

No meals after 2 pm. Lol frick no. I do too much physical work for that.

IF is a tool to manage calorie intake. That’s it.

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IF is a tool to manage calorie intake. That’s it.

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In general I agree with you but if some afternoon fasting can supplement or outright replace medication in prediabetic patients, it's with a look

That's really well put together

My guess is it's designed to mimic what the average American diet looks like.

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It's real science regardless of what Twitter trolls like Layne Norton 

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I don't want to completely derail this thread but Layne's not typically one to ignore good science. I think he generalizes to provide info to gen pop but things like this point to helping those with conditions. For a reasonably healthy overweight person, the majority of benefits will come from caloric restriction and weight loss and they won't see much benefit from fasting unless it is used as a tool for caloric restriction and/or helps with adherence

I agree. And as 777 noted he had a Dom D chapter in his book. I had to stop following on Twitter though because he's so bombastic and chooses his criticism victims with all the precision of an A bomb.

I do want to see more evidence on the more precise benefits of fasting v mere caloric restriction. The studies are out there in rodents and as we've seen are building in human studies which are inherently difficult to design and implement.

I also what to see more studies re: feeding timing vis-a-vis chronotype and circadian rhythm. Unlike most lab rats and mice, for the most part, humans have differing cronotypes (which makes sense evolutionary). Also as noted it would be nice to see fasting studies combined with various macro compositions. Attia does the "nothing burger," for example. Multi-day fast sandwiched beteen keto days.

I'm a big fan of compiling n=1ers as pilot type studies. They are in many ways potentially more reliable than a lot of questionnaire epi.

But most people who faithfully n=1 and report it are "healthy subjects," so that's a big bias and flaw.

The double blinds are in the works though.

I think we're going to be overwhelmed with good evidence of the overall health benefits of not just caloric restriction or even just TRF and macros, but specific time windows per chronotype. Just an informed hunch.

I hate the calorie=calorie v. "metabolic health" debate. Both are very clearly true.



And more on

Thanks for sharing. I enjoy the mental sharpness that comes with a mild, 14-18 hr fast.