Anyone listen to Dr. Pradip on insulin resistance?

no because like most Indians(dot not feather) he is full of complete shite.

I didnt need Sanjeet to tell me fasting works great.

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I don't have time for the full video right now but what exactly would even be controversial about these claims?

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All of them?

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Fasting lets insulin levels drop so your body can access stored energy

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This one for starters. Aside from it being an obvious thing to state (not eating makes you burn fat), it doesn't matter over the long haul.

If you eat the same amount of calories/macros per day, your body would burn the same amount of energy regardless of meal timing: either you ate the right amount of food to burn fat or you did not.

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Eating constantly keeps insulin high, which stops your body from burning fat.

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Same exact response here. Eating "constantly" but staying within a set diet will result in the same amount of "fat burning" as fasting part of the day and then eating the same diet.

If fasting helps someone stay within their caloric goal for the day, more power to them, but its not a magical fat burning tool.

I don't follow this Doctor but its an established fact that insulin is the defacto 'fat storage' hormone.

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Although many factors affect fat cells, the hormone insulin exerts dominant anabolic control. Insulin decreases the circulating concentration of all major metabolic fuels by stimulating glucose uptake into tissues, suppressing release of fatty acids from adipose tissue, inhibiting production of ketones in the liver, and promoting fat and glycogen deposition.

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I tell people this when asked how to lose weight.

When you eat something, your breakfast, lunch, dinner, an apple, sandwich, cookies, cakes, chips...your pancreas cranks up and starts to release...insulin.

This is why snacking or grazing all through the day and late at night is so detrimental for health and weight gain.

Plus add in the garbage and crap that is our food supply, it makes it even worse.

And to compound it even worse, a lot of 'healthy' food is devoid of vital macros, vitamins, minerals, polyphenols that our bodies need.

There is a term out there called 'skinny-fat.' You see folks who are thin, they have little or no butt, skinny legs but a big old pot gut.

Intermittent fasting along with a good healthy diet that is low in carbs and sugars will go a long way in creating a metabolically healthy life.

This doctor, an endocrinologist, Gerald "Jerry" Reaven, MD, is the first person who coined the term 'Syndrome X' which we now refer to as insulin resistance.

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In the 1950s, when Reaven started out as a researcher, it was believed that there was only one type of diabetes and that it was caused by a lack of insulin.

"In the late '70s early '80s, there was a lot of controversy about insulin resistance, and Jerry was not shy about standing up and sharing his opinions," said Frederic Kraemer, MD, professor and chief of endocrinology, gerontology and metabolism at Stanford. "He was tenacious when it came to defending his scientific observations. He didn't like to accept opinions; he liked to accept facts - facts generated from well-controlled scientific investigations."

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Then we have the established metabolic process of autophagy:

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The term autophagy refers to cellular mechanisms associated with self-eating and diverse homeostatic phenomena. Activation of autophagy helps the host cells to eliminate misfolded, aggregated proteins and injured organelles [1]. Besides its role in cellular homeostasis, autophagy is actively involved in the development, differentiation, and regenerative potential of several embryonic and adult cells [2,3]. In eukaryotes, the autophagy machinery and proteasomes are the 2 main degradation systems for the elimination of digested molecular cargo.

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Medical science owes researchers like Drs Albert Claude, Christian de Duve and George E. Palade and Dr. Yoshinori Ohsumi for understanding of cellular functions and autophagy.

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