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re: Biology, Chemist and Biochemist OTers: Help me understand weight loss.

Posted on 4/3/17 at 9:12 am to
Posted by Hu_Flung_Pu
Central, LA
Member since Jan 2013
22237 posts
Posted on 4/3/17 at 9:12 am to
Watch this. It will show you how your body gets rid of fat. This is based on regular eating and not ketosis.

This video is on ketosis. It is not really a scientific approach but info is there to get a good grasp on what is happening.

This video is more scientific but has a really stupid background music.

Ketosis is just a different energy system. Fat has more potential energy in a gram than glucose does but does not provide the "instant" energy that glucose does. You have to deplete your glucose to get into ketosis. If you have ever tried out ketosis you will see that you will "level out" your energy levels and have a sustained release of energy throughout the day instead of peaks from glucose. There is no doubt that glucose is very beneficial for exercising but IMO a timed carb meal is better than eating carbs throughout the day. I believe the diet is called TKD where you would time your carbs right before or after the workout and be in ketosis the rest of the time.

I don't know about the overall "weight" loss of ketosis vs diets with carbs but I do hold on to more weight with carbs. I get bloated.

The way I approach my diet is to be in mindset of ketosis but not worrying about being in ketosis. I have my cheat meals throughout the week but I treat them as treats. I try to eat a fairly large carb/calorie meal before days where I deadlift or squat. The other days, I just consume a little bit of carbs. I am in maintenance right now but if I were to cut, I'd just reduce the carbs a little bit more and add in some cardio if the reduction of carbs slows down.

Basically, treat your food as fuel and use it how it was intended. Carbs are for energy. If you don't require the energy the carbs provide, don't eat them or eat them sparingly.
This post was edited on 4/3/17 at 9:14 am
Posted by Hu_Flung_Pu
Central, LA
Member since Jan 2013
22237 posts
Posted on 4/3/17 at 9:16 am to
quote:

A lot of this is actually related to cortisol production. Cortisol is a stress hormone that gets released with certain levels of exertion, and can lead to fat retention.


That zone is for the heart rate. Increased heart rate leads to more blood flow and excess breathing. Watch my first video in my other post on the science behind fat burning.
Posted by Capital Cajun
Over Yonder
Member since Aug 2007
5528 posts
Posted on 4/3/17 at 9:28 am to
quote:

Move more, eat less


This plus cut out or cut way down on the sugar and grains.
Posted by Bmath
LA
Member since Aug 2010
18692 posts
Posted on 4/3/17 at 9:29 am to
Again, it has to with stress on the body and cortisol production.

Our bodies are complex. It's why most things work until they don't.
This post was edited on 4/3/17 at 9:30 am
Posted by MBclass83
Member since Oct 2010
9444 posts
Posted on 4/3/17 at 9:30 am to
Don't do it for long periods of time. It can be hard on your kidneys.
Posted by MontyFranklyn
T-Town
Member since Jan 2012
23836 posts
Posted on 4/3/17 at 10:09 am to
quote:

Hu_Flung_Pu

The third video is the video I watched. It is the one referencing. Lol
Posted by MontyFranklyn
T-Town
Member since Jan 2012
23836 posts
Posted on 4/3/17 at 3:33 pm to
quote:

Calories in, calories out baw

True. You do realize that if you cut carbs(sugar included), you simultaneously cut your calories as well. Per gram, there are more calories in carbs than in proteins.
Posted by Sao
East Texas Piney Woods
Member since Jun 2009
66133 posts
Posted on 4/3/17 at 3:36 pm to

As others have said, it's all about caloric burn. a calorie is 1 unit of energy. If you eat 1000 calories and burn 1200, the reserve 200 comes from your fat cell stores. Weight loss is seriously as easy as that.
Posted by jakedel12
Dallas, Texas
Member since Nov 2006
1449 posts
Posted on 4/3/17 at 3:39 pm to
quote:

This plus cut out or cut way down on the sugar and grains.


Ketosis^^^^^^
Posted by tuptiger
Member since Jan 2008
4314 posts
Posted on 4/3/17 at 3:47 pm to
Basically, your body is constantly breaking down glucose. Glucose gets oxidized and goes through glycolysis, the Citric Acid Cycle and the Electron Transport Chain. Fatty Acid Oxidation can feed into these pathways.

At the Citric Acid Cycle, oxaloacetate combines with ACOA to form citrate. If you starve yourself, however, there will be a decrease in oxaloacetate production, which means it can't combine with acetyl COA to produce citrate and produce ATP this way.

Your body, to make up for the discrepancy, begins funneling in fat to burn as energy. Ketone bodies are important for brain and vital organ function if you're starving.

To make a long story short, if you're low on sugar, either glucose or glycogen, your body burns fat. This is ketosis. It keeps funneling in triglycerides from adipose tissue.

It's sound scientifically to lead to weight loss.

Sympathetic nervous system neurotransmitters also operate in this way. I think this is a way to lose weight.
This post was edited on 4/3/17 at 3:53 pm
Posted by Goldrush25
San Diego, CA
Member since Oct 2012
33794 posts
Posted on 4/3/17 at 4:03 pm to
quote:

I deduced that your body runs of a primary fuel and a back up fuel. Glucose is the primary fuel. Glucose is produced in your body from carbs and sugar. If the "tank" for glucose fuel fills, due to you not burning it, the excess glucose is then stored into fat cells. Your body will only burn these fat reserves when the glucose "tank" is empty.


Pretty good synopsis. However it is a little more complicated than that. It's not either/or when you're exercising, you're burning both fat and glucose.

The intensity of exercise can dictate in what ratio your body burns glucose and fat. During low intensity exercise your body will tend to burn less fat. High intensity interval training you'll burn more.
Posted by BiggerBear
Redbone Country
Member since Sep 2011
2933 posts
Posted on 4/3/17 at 4:42 pm to
quote:

Wanna lose wt?
I have a foolproof 2-step weight loss program.

Step #1 - Eat Less.

Step #2 - Move around more.



Almost. If you want to lose weight, eat less. You can't outrun your fork. Ultimately, you can sit on your arse and lose weight if you reduce your food intake enough.
Posted by iAmBatman
The Batcave
Member since Mar 2011
12382 posts
Posted on 4/3/17 at 8:01 pm to
quote:

Per gram, there are more calories in carbs than in proteins.


That is blatantly false. There are 4 calories per gram of carbohydrate or protein.
Posted by MiloDanglers
on a dock on a bay
Member since Apr 2012
6547 posts
Posted on 4/3/17 at 8:37 pm to
quote:

In all the other diets fat is typically the last thing to lose because it is the hardest thing to breakdown into glucose. Sugar is inflammatory for your whole body. Cancer runs on glucose. Literally almost everything bad healthwise comes from sugar and grains. If you aren't using the energy immediately it turns into fat because it takes no energy to breakdown sugar and grains.


Came for the bro science

Left satisfied
Posted by MontyFranklyn
T-Town
Member since Jan 2012
23836 posts
Posted on 4/4/17 at 9:40 am to




quote:

It theoretically may be impossible to get cancer while in ketosis since you will have no glucose for the cancer to use (this is a big leap of faith but it is known to help treat cancer). What I've read says no one can get approval to do an actual study with human subjects on whether a ketosis diet can treat cancer. In all the other diets fat is typically the last thing to lose because it is the hardest thing to breakdown into glucose. Sugar is inflammatory for your whole body. Cancer runs on glucose. Literally almost everything bad healthwise comes from sugar and grains. If you aren't using the energy immediately it turns into fat because it takes no energy to breakdown sugar and grains.


Not entirely true.

LINK

quote:

The MIT researchers found that glucose accounts for just 10–15% of the carbon found in cancer cells, whereas glutamine contributes about 10% of the carbon. Instead, the researchers found that as a group, amino acids (excluding glutamine) contribute the majority of the carbon atoms found in new cells and 20–40% of the total mass
Posted by MontyFranklyn
T-Town
Member since Jan 2012
23836 posts
Posted on 4/4/17 at 9:45 am to
quote:

That is blatantly false. There are 4 calories per gram of carbohydrate or protein.
Yeah, that was my bad. I didn't read the entire portion of the article.


quote:

Carbohydrates, proteins, and fats supply 90% of the dry weight of the diet and 100% of its energy. All three provide energy (measured in calories), but the amount of energy in 1 gram (1/28 ounce) differs: 4 calories in a gram of carbohydrate or protein. 9 calories in a gram of fat.
Posted by Hu_Flung_Pu
Central, LA
Member since Jan 2013
22237 posts
Posted on 4/4/17 at 9:50 am to
I think they actually narrowed it down that protein had 4.1 calories.
Posted by zatetic
Member since Nov 2015
5677 posts
Posted on 4/4/17 at 10:06 am to
quote:

Not entirely true.


Just for the record that doesn't refute anything I said. I may have exaggerated that cancer runs on glucose. My statement, "It theoretically may be impossible to get cancer while in ketosis since you will have no glucose for the cancer to use" was not refuted by that article, which was my point.

They won't allow ketosis studies to be done anyways.
Posted by MontyFranklyn
T-Town
Member since Jan 2012
23836 posts
Posted on 4/4/17 at 10:13 am to
quote:


Just for the record that doesn't refute anything I said. I may have exaggerated that cancer runs on glucose. My statement, "It theoretically may be impossible to get cancer while in ketosis since you will have no glucose for the cancer to use" was not refuted by that article, which was my point.

They won't allow ketosis studies to be done anyways.
I do think it would be harder for cancer cells to survive and grow without glucose, but it seems that amino acids may play a larger part of their existence.
Posted by Yellerhammer5
Member since Oct 2012
10854 posts
Posted on 4/4/17 at 10:24 am to
quote:


While there is truth to that, if you could optimize weight loss, then why wouldn't you?

Ketosis supercharges weight loss.


Because it doesn't train you to eat properly and maintain your weight loss. Losing and gaining large amounts of weight isn't healthy and most people will eventually gain all lost weigh back (and frequently more). People should aim for 1-2 pounds per week at most and learn to develop healthy, sustainable eating habits.
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