re: Play calling will be the difference maker

it's actually an easy concept: if you're physically and athletically superior to your opponent, then do your thing and make them try to stop you.
If you're not physically and athletically superior, then it's stupid to just try to ram it down their throats. You need to keep them on their heels, and that means making them unsure what we're going to do. Misdirection, counters, screens, draws, throwing on 1st down, etc. Keep your opponent guessing. It's not that hard, but Stud/Les aren't catching on.
Run where the defense ain't.