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I’ve started down the mRNA vaccine rabbit hole
Posted on 8/21/21 at 12:26 pm
Posted on 8/21/21 at 12:26 pm
Since I have a degree in molecular bio I decided to educate myself further on exactly how these vaccines work. The first question I had was obvious. How does the viral mRNA survive once inside the cell to be translated into a protein? For those unfamiliar, the cell has pathways to detect both foreign RNA and DNA, and upon detection the cell elicits responses to dispose of the invader. It is this response that creates the greatest challenge in developing an effective mRNA vaccines. So far several delivery methods have been developed, but their effectiveness can vary greatly.
This is where we are now and it quite possibly the reason talk of a third booster shot is now being mentioned and mask mandates are popping back up. There are so many factors that play a part in how effective these vaccines are. Purity of the mRNA, a person’s innate immunity, and delivery method are all factors. Hell it’s quite possible that people are being given the vaccine and in some cases it’s being destroyed in the cytoplasm before it’s even translated or it’s being translated on a much smaller scale than what they’d hoped. If that’s the case you’d still be at risk of Covid despite the fact that you’re fully vaccinated.
These challenges are all part of the reason why these vaccines are still considered experimental.
This is where we are now and it quite possibly the reason talk of a third booster shot is now being mentioned and mask mandates are popping back up. There are so many factors that play a part in how effective these vaccines are. Purity of the mRNA, a person’s innate immunity, and delivery method are all factors. Hell it’s quite possible that people are being given the vaccine and in some cases it’s being destroyed in the cytoplasm before it’s even translated or it’s being translated on a much smaller scale than what they’d hoped. If that’s the case you’d still be at risk of Covid despite the fact that you’re fully vaccinated.
These challenges are all part of the reason why these vaccines are still considered experimental.
20
Posted on 8/21/21 at 12:30 pm to Blizzard of Chizz
we only need to look at the difficulty our medical researchers have dealt with trying to find effective treatments for the common cold and flu to understand the difficulty of finding safe and effective treatments fro this genetically engineered virus. 
Posted on 8/21/21 at 12:31 pm to Blizzard of Chizz
Just get the vaccine don’t worry yourself about all that!
Posted on 8/21/21 at 12:31 pm to Blizzard of Chizz
In your research rabbit hole, did you get to the part where the PEG reactors in all mRNA vaccines are produced exclusively by a Chinese company called Sinopeg? If not, keep going down said RH till you get to that revelation. And I promise you, your research will then take you on a magic carpet ride of disbelief from that point on.
Posted on 8/21/21 at 12:31 pm to Blizzard of Chizz
Odds of a human engineered tech defeating millions of years of viral evolution on the first at-bat seems a bit…hubristic.
I’ll go with my immune system and it’s 100,000 years of evolution. Live to see the 7th inning stretch at least.
I’ll go with my immune system and it’s 100,000 years of evolution. Live to see the 7th inning stretch at least.
Posted on 8/21/21 at 12:31 pm to Blizzard of Chizz
quote:
These challenges are all part of the reason why these vaccines are still considered experimental.
Which is why vaccine passports and mandates are asinine.
As well as mask mandates.
Posted on 8/21/21 at 12:32 pm to Tomatocantender
quote:
In your research rabbit hole, did you get to the part where the PEG reactors in all mRNA vaccines are produced exclusively by a Chinese company called Sinopeg? If not, keep going down said RH till you get to that revelation. And I promise you, your research will then take you on a magic carpet ride of disbelief from that point on.
Sane America First patriots can't be shocked at this point....we expect nothing but madness going forward.
Posted on 8/21/21 at 12:36 pm to Blizzard of Chizz
quote:A ton of vaccines require 2 or 3 shots and regular boosters.
This is where we are now and it quite possibly the reason talk of a third booster shot is now being mentioned
Posted on 8/21/21 at 12:37 pm to Tomatocantender
I’ve only just begun reading. Mainly I was curious how the vaccine survived in the cell. The body recognizes self and what isn’t recognized is considered foreign thus an immune response occurs. So if you introduce viral mRNA into the cellular cytoplasm, how does it survive in order to be translated? The translated protein is what is being created to induce an immune response. Well, the studies I’ve read so far describe that as one of the biggest challenges to their effectiveness.
Posted on 8/21/21 at 12:38 pm to SelaTiger
quote:
Just get the vaccine don’t worry yourself about all that!
I went ahead and took the difficult path and got Covid. The real unknown is how long is natural immunity effective. The docs I spoke with seem unvomfortable but somewhere from 3-6 mos and believe it would benefit to get the jab around 3 months after Covid exposure. Who fricking knows. The questions seems to be an uncomfortable one FWIW.
Posted on 8/21/21 at 12:38 pm to Blizzard of Chizz
The Novavax vaccine isn't mRNA. It's manufactured covid spike proteins that trigger our immune system and flag it as foreign threat.
One of the weaknesses of these vaccines may be that they are so precisely manufactured that they are all exactly alike. A normal infection would be apt to have some variety within the virus population which ought to create a wider spectrum of an immune response.
One of the weaknesses of these vaccines may be that they are so precisely manufactured that they are all exactly alike. A normal infection would be apt to have some variety within the virus population which ought to create a wider spectrum of an immune response.
Posted on 8/21/21 at 12:41 pm to Blizzard of Chizz
how many animal trials have been successful?
Posted on 8/21/21 at 12:42 pm to Blizzard of Chizz
Phizer vax was given to nursing home patients. 1 month after getting vax 84% had antibodies. 6 months after vax 30% had antibodies. The vax does not last.
Also how does your body kill the covid S1 and S2 proteins?
IT seems it kills the S2 proteins, but the S1 proteins remain. Ivermectin helps kill the S1 proteins. The sooner you get Ivermectin the fewer doses you will need.
Also how does your body kill the covid S1 and S2 proteins?
IT seems it kills the S2 proteins, but the S1 proteins remain. Ivermectin helps kill the S1 proteins. The sooner you get Ivermectin the fewer doses you will need.
Posted on 8/21/21 at 12:42 pm to Bass Tiger
quote:
we only need to look at the difficulty our medical researchers have dealt with trying to find effective treatments for the common cold and flu to understand the difficulty of finding safe and effective treatments fro this genetically engineered virus.
There is not a lot common in the common cold other than a category defining a wide collection of viruses. One of the common cold viruses is from the set of 5 coronaviruses that are part of the category. German studies identified it as the reason that so many people where asymptomatic or had very mild fleeting cases of covid.
Posted on 8/21/21 at 12:45 pm to Auburn1968
quote:
The Novavax vaccine isn't mRNA.
Absolutely correct, however there's one small problem. Novavax is not emergency approved yet, therefore it's not in circulation, not an option ATM. And despite what you might be hearing about October, November drop date etc., there's no guarantee that it gets that nod anytime soon.
Posted on 8/21/21 at 12:45 pm to mmcgrath
quote:
A ton
Can you be more specific what a ton is? Maybe a link to a list of the ton of boosters? Thanks, doing research on all of this for my family.
Posted on 8/21/21 at 12:48 pm to obdobd918
quote:
Phizer vax was given to nursing home patients. 1 month after getting vax 84% had antibodies. 6 months after vax 30% had antibodies. The vax does not last.
That's not how our immune system works. Our immune system doesn't keep producing antibodies after a threat is defeated and antibodies don't last forever. However, our T and B cells remember the threat and crank up antibody production if it sees it again.
To see if the immunity is fading over time recently vaccinated would have to be compared to early vaccinated cases and outcomes where all other things are equal.
Posted on 8/21/21 at 12:49 pm to Blizzard of Chizz
Since I have a degree in molecular bio
Ehhh …. Did you sleep at a holiday inn express last night?
Ehhh …. Did you sleep at a holiday inn express last night?
Posted on 8/21/21 at 12:51 pm to Tomatocantender
quote:
Absolutely correct, however there's one small problem. Novavax is not emergency approved yet, therefore it's not in circulation, not an option ATM. And despite what you might be hearing about October, November drop date etc., there's no guarantee that it gets that nod anytime soon.
All true. It does look much more promising than the mechanisms of action of the mRNA or chimp virus of J&J though.
Posted on 8/21/21 at 12:52 pm to mmcgrath
quote:
A ton of vaccines require 2 or 3 shots and regular boosters.
Which ones specifically?
I'm expecting you to list about 20
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