- My Forums
- Tiger Rant
- LSU Recruiting
- SEC Rant
- Saints Talk
- Pelicans Talk
- More Sports Board
- Fantasy Sports
- Golf Board
- Soccer Board
- O-T Lounge
- Tech Board
- Home/Garden Board
- Outdoor Board
- Health/Fitness Board
- Movie/TV Board
- Book Board
- Music Board
- Political Talk
- Money Talk
- Fark Board
- Gaming Board
- Travel Board
- Food/Drink Board
- Ticket Exchange
- TD Help Board
Customize My Forums- View All Forums
- Show Left Links
- Topic Sort Options
- Trending Topics
- Recent Topics
- Active Topics
Started By
Message
Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein
Posted on 2/2/23 at 3:03 am
Posted on 2/2/23 at 3:03 am
quote:
The SARS-CoV-2 virus is still spreading worldwide, and there is an urgent need to effectively prevent and control this pandemic. This study evaluated the potential efficacy of Egg Yolk Antibodies (IgY) as a neutralizing agent against the SARS-CoV-2. We investigated the neutralizing effect of anti-spike-S1 IgYs on the SARS-CoV-2 pseudovirus, as well as its inhibitory effect on the binding of the coronavirus spike protein mutants to human ACE2. Our results show that the anti-Spike-S1 IgYs showed significant neutralizing potency against SARS-CoV-2 pseudovirus, various spike protein mutants, and even SARS-CoV in vitro. It might be a feasible tool for the prevention and control of ongoing COVID-19.
LINK
You paying attention yet?
8
Posted on 2/2/23 at 3:34 am to GumboPot
The conspiracy on chicken feed not producing eggs was funny before. Now it’s scary.
I have chickens and they stopped laying eggs a few weeks ago. Probably cause of the cold weather, but still creepy.
I have chickens and they stopped laying eggs a few weeks ago. Probably cause of the cold weather, but still creepy.
Posted on 2/2/23 at 3:34 am to GumboPot
quote:
Egg Yolk Antibodies (IgY)
Do you get these from eating eggs or is this just something you can look at in the lab?
Posted on 2/2/23 at 3:53 am to GumboPot
Someone tell me if I'm wrong but it seems the IgY would have to be conjured up in a lab, then given to people like monoclonals, or maybe some other way like an aerosol. We're not going to get protection from simply eating eggs, correct?
From the manuscript:
Here, we purified anti-spike-S1 IgYs from hens that were immunized with the S1 domain of the SARS-CoV-2 spike protein and interrogated their ability to neutralize SARS-CoV-2 pseudovirus using Hela cells with overexpressed human ACE2.
In summary, the anti-Spike-S1 IgYs showed significant neutralizing potency against SARS-CoV-2 pseudovirus, various S mutants, and even SARS-CoV in vitro. However, the safety and efficacy of the IgYs still needs further interrogation in animal models.
At present, the SARS-CoV-2 virus is still spreading around the world, and there is much to be done to prevent and control the pandemic. The use of IgYs in aerosol or spray formulations on the respiratory tract, the oral cavity, and even the digestive tract may be a worthwhile strategy. It might prevent the invasion of the SARS-CoV-2 virus through the natural infection route. Long-term control of the SARS-CoV-2, however, will require a combination of active and passive immunization tools, drug therapy, and other preventive measures.
From the manuscript:
Here, we purified anti-spike-S1 IgYs from hens that were immunized with the S1 domain of the SARS-CoV-2 spike protein and interrogated their ability to neutralize SARS-CoV-2 pseudovirus using Hela cells with overexpressed human ACE2.
In summary, the anti-Spike-S1 IgYs showed significant neutralizing potency against SARS-CoV-2 pseudovirus, various S mutants, and even SARS-CoV in vitro. However, the safety and efficacy of the IgYs still needs further interrogation in animal models.
At present, the SARS-CoV-2 virus is still spreading around the world, and there is much to be done to prevent and control the pandemic. The use of IgYs in aerosol or spray formulations on the respiratory tract, the oral cavity, and even the digestive tract may be a worthwhile strategy. It might prevent the invasion of the SARS-CoV-2 virus through the natural infection route. Long-term control of the SARS-CoV-2, however, will require a combination of active and passive immunization tools, drug therapy, and other preventive measures.
Posted on 2/2/23 at 4:13 am to GumboPot
Wow
Posted on 2/2/23 at 5:07 am to POTUS2024
Yeah no thanks!!
Paaassss
Paaassss
Posted on 2/2/23 at 5:19 am to POTUS2024
quote:No.
Do you get these from eating eggs
Posted on 2/2/23 at 5:23 am to POTUS2024
quote:Correct.
We're not going to get protection from simply eating eggs, correct?
Plus there is an implied differential between effectiveness vs pseudoCV19 as opposed to CV19, and there is no claim of any effect vs CV19 in vivo.
Posted on 2/2/23 at 7:19 am to Big Gorilla
My chickens stopped laying about six months ago. I thought it was because they had just gotten too old but in the past month two of them have started laying again.
Yeah. That's weird.
Yeah. That's weird.
Posted on 2/2/23 at 7:21 am to GumboPot
eAt MoAR bUgS
Posted on 2/2/23 at 7:24 am to Captain Rumbeard
I think chickens are know to lay less during fall and winter due to cooler temps and shorter days. Totally normal
Posted on 2/2/23 at 7:27 am to SingleMalt1973
They do.
This is January.
When these chickens were laying regularly they'd slow down about now. These just started laying again after no eggs for the last six months. Stopped laying last summer.
This is January.
When these chickens were laying regularly they'd slow down about now. These just started laying again after no eggs for the last six months. Stopped laying last summer.
Posted on 2/2/23 at 7:35 am to GumboPot
This is as dumb as when people on social media think their brooms are standing up because the stars are in proper alignment.
Posted on 2/2/23 at 8:14 am to SingleMalt1973
quote:
I think chickens are know to lay less during fall and winter due to cooler temps and shorter days. Totally normal
This is why I am not too concerned, but its still weird. They were laying just fine and then boom...Nothing.
Posted on 2/2/23 at 8:35 am to GumboPot
q said sunlight kills
> sunlight
> eggs
> sunny side up
wrap it up boys
> sunlight
> eggs
> sunny side up
wrap it up boys
Posted on 2/2/23 at 9:15 am to GumboPot
That ties up another loose end nicely, now doesn't it?
Page 1 of 1
Popular
Back to top
Follow TigerDroppings for LSU Football News