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Gilead remdesivir study published in NEJM: two third of severe ill patients improved

Posted on 4/10/20 at 7:01 pm
Posted by Northwestern tiger
Long Island NY
Member since Oct 2005
23485 posts
Posted on 4/10/20 at 7:01 pm
quote:

In this cohort of patients hospitalized for severe Covid-19 who were treated with compassionate-use remdesivir, clinical improvement was observed in 36 of 53 patients (68%). Measurement of efficacy will require ongoing randomized, placebo-controlled trials of remdesivir therapy.

LINK
Posted by upgrayedd
Lifting at Tobin's house
Member since Mar 2013
134965 posts
Posted on 4/10/20 at 7:05 pm to
The media will call this irresponsible kook science
Posted by oilattorney4lsu
Baton Rouge
Member since Jul 2009
2068 posts
Posted on 4/10/20 at 7:20 pm to
quote:

two third of severe ill patients improved


Where did you get the “severe” part? Are all hospitalized patients in the study considered severe? Or were some moderate but being monitored in the hospital?

I’m not trying to argue with you just trying to analyze this article. Were 2/3rds going to recover with no medical treatment anyway? I wish it was a higher percentage than 68%.

Posted by Fun Bunch
New Orleans
Member since May 2008
116328 posts
Posted on 4/10/20 at 7:28 pm to
Depending on the severity of the patients that’s good news.
Posted by Adam Banks
District 5
Member since Sep 2009
32071 posts
Posted on 4/10/20 at 8:55 pm to
Game changer.
Posted by Ace Midnight
Between sanity and madness
Member since Dec 2006
89641 posts
Posted on 4/10/20 at 9:02 pm to
quote:

remdesivir


This is the key late stage treatment.

The HCQ/Z-pak/Zinc cocktail needs to be earlier - when the case gets serious, but before desat levels get into ventilator areas.
Posted by Jimmy2shoes
The South
Member since Mar 2014
11004 posts
Posted on 4/10/20 at 9:37 pm to
gild
Posted by Jake88
Member since Apr 2005
68441 posts
Posted on 4/10/20 at 11:24 pm to
Hospitals in New Orleans have been using it in their COVID protocol since mid March.
Posted by Roger Klarvin
DFW
Member since Nov 2012
46590 posts
Posted on 4/11/20 at 12:12 am to
It’s a meaningless study without a control group. The only conclusions you can draw from this is some people got remdesivir and some of them got better while others didn’t.

In normal times a paper like this gets rejected in 12 seconds by a journal of such repute.
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