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Started By
Message
Losartan and HydroxyChloroquine
Posted on 3/19/20 at 1:16 pm
Posted on 3/19/20 at 1:16 pm
Losartan and HydroxyChloroquine are being checked for China-virus cure/treatment.
Most here have heard about Hydroxychrloroquine being used to fight China-Virus.
Some may not have heard that trials using the blood pressure medicine of Losartan is also being done.
LINK
Most here have heard about Hydroxychrloroquine being used to fight China-Virus.
Some may not have heard that trials using the blood pressure medicine of Losartan is also being done.
quote:
Quote:
Researchers say Losartan, an enzyme receptor, could prevent the virus from binding to host cells in the victim's body, possibly preventing further or future infections. Hydroxychloroquine, used to treat malaria in many countries, could possibly suppress the proteins that cause deadly inflammation in victims, according to Reuters.
A 1,500-patient trial began this week testing the use of hydroxychloroquine, according to the news service, while two trials testing the use of losartin are reportedly ongoing.
LINK
10
Posted on 3/19/20 at 1:19 pm to TurkeyBaconLeg
So...if we already take Losartan, we are good to go?
Posted on 3/19/20 at 1:21 pm to SSpaniel
quote:
So...if we already take Losartan, we are good to go?
Maybe. Did the trials test only Losartan, or also with the variant including HCTZ?
And a follow-up: if Losartan works, what about Valsartan? (I take the latter)
Posted on 3/19/20 at 1:22 pm to TurkeyBaconLeg
quote:
Losartan
Already on it.
Posted on 3/19/20 at 1:22 pm to TurkeyBaconLeg
nice. I already take it and its cheap.
Posted on 3/19/20 at 1:26 pm to TurkeyBaconLeg
Obligatory
Posted on 3/19/20 at 1:26 pm to Quidam65
quote:
if Losartan works, what about Valsartan? (I take the latter)
Kinda the same thing here... I actually take Telmisartan. They all do the exact same thing, though.
Posted on 3/19/20 at 1:27 pm to TurkeyBaconLeg
I take it there’s nothing OTC that has the effective components in it?
Posted on 3/19/20 at 1:28 pm to MeatCleaverWeaver
I thought they said ACEs and ARBs were bad to take with Corona?
Posted on 3/19/20 at 1:28 pm to TurkeyBaconLeg
Losartan is actually free if you have good insurance.
Bad news: There was a bunch contaminated last year because the Chinese thought it was smart to make rocket fuel in the same factory they make prescription medicine and it was one of those affected. There was actually a shortage for a while last year.
Bad timing...
(Plus - yet another thing they only/mainly make in China...)
Bad news: There was a bunch contaminated last year because the Chinese thought it was smart to make rocket fuel in the same factory they make prescription medicine and it was one of those affected. There was actually a shortage for a while last year.
Bad timing...
(Plus - yet another thing they only/mainly make in China...)
Posted on 3/19/20 at 1:29 pm to Cosmo
quote:
I thought they said ACEs and ARBs were bad to take with Corona?
There was concern about ACE inhibitors. I didn't see anything about ARBs, but I could have missed it.
(ETA: Extra irony, I can't take "Ace" inhibitors.)
This post was edited on 3/19/20 at 1:30 pm
Posted on 3/19/20 at 1:37 pm to SSpaniel
quote:
So...if we already take Losartan, we are good to go?
Just dug into that question as it is interesting. There are some researches suggesting the opposite.
Are patients taking ACEi and ARBS more likely to coctract virus?
quote:
We suggest that patients with cardiac diseases, hypertension, or diabetes, who are treated with ACE2-increasing drugs, are at higher risk for severe COVID-19 infection and, therefore, should be monitored for ACE2-modulating medications, such as ACE inhibitors or ARBs. Based on a PubMed search on Feb 28, 2020, we did not find any evidence to suggest that antihypertensive calcium channel blockers increased ACE2 expression or activity, therefore these could be a suitable alternative treatment in these patients.
The theory is: if you take these meds, your body responds by making more ACE2. This would create more sites for possible attachments. If you had not previously taken these meds you would have normal receptor population and they may work to reduce risk.
PLEASE BEAR IN MIND: This is all supposition and the authors are trying to spark research to validate or disprove. I did not share this to cause undue concern, but rather suggest a wait and see approach.
Posted on 3/19/20 at 1:43 pm to IslandBuckeye
Should I fill another 90 day supply just to be sure??
Posted on 3/19/20 at 1:52 pm to IslandBuckeye
That may occur for people who are chronically on it. But, in the short term in a person who has never taken it, it would block the receptors and the virus attachment.
Posted on 3/19/20 at 1:53 pm to Ace Midnight
quote:
Bad news: There was a bunch contaminated last year because the Chinese thought it was smart to make rocket fuel in the same factory they make prescription medicine and it was one of those affected. There was actually a shortage for a while last year.
A lot of the "sartans" went through that. Mine was OK though, apparently Aurobindo in Hyberabad (India) has good quality control. (Though this year my pharmacy switched suppliers to Mylan)
Posted on 3/19/20 at 1:54 pm to ugasickem
quote:
nice. I already take it and its cheap.
Not for long.
Gonna be runs on it like TP.
Posted on 3/19/20 at 1:55 pm to TurkeyBaconLeg
Losartan will go back to being on backorder again soon too..
we had been out of that for a few weeks last year bc of the recall
Hope they have their supplies shored up again before this
we had been out of that for a few weeks last year bc of the recall
Hope they have their supplies shored up again before this
Posted on 3/19/20 at 1:55 pm to Ace Midnight
quote:
There was a bunch contaminated last year because the Chinese
Ya don't say...
Actually, that's why my doc switched me from Losartan to Telmisartan.
Posted on 3/19/20 at 1:55 pm to DieSmilen
In MY opinion, yes. I would never suggest changing prescribed courses of medicine. It would also ensure you have them in case crazy people create a bogus shortage.
I am a clinical pharmacist working in a hospital. I find the topic fascinating. If you are on good terms with your doc, by all means discuss it with him/her. Again this is all theoretical at this point. The benefits of ARBs (ending in -sartan) have well documented benefits for high BP, heart failure, and kidney disease (diabetics).
I am a clinical pharmacist working in a hospital. I find the topic fascinating. If you are on good terms with your doc, by all means discuss it with him/her. Again this is all theoretical at this point. The benefits of ARBs (ending in -sartan) have well documented benefits for high BP, heart failure, and kidney disease (diabetics).
Posted on 3/19/20 at 1:58 pm to TurkeyBaconLeg
Why are so many on here on Losartan?
I know a few folks on it but they're either very old or fatties that have BP issues.
I know a few folks on it but they're either very old or fatties that have BP issues.
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