Fantasy Impacts from changes with the Titans and Chargers

12 team league: QB, 2RB, 2WR, TE, Flex, DST, K
I have Pick 6. Snake draft order.

Last year I was able to get Keenan Allen in the middle of the draft. I took Allen as a potential high reward/relatively low risk given the draft position 7th round. Paid off for me big time as he was healthy really for the first full season of his career. My concern is Mike Williams being healthy and having a full camp and preseason. With the loss of Hunter Henry very possibly for the season, should I worry about Williams taking targets from Allen? I’m sure he won’t fall to the 7th round again, is Allen a round 2-3 receiver?

I’m high on the Titans in general this year. They’ve brought in Matt LeFleur from the Rams. With Mariota healthy I think this could really be a great combo and a much improved offense. I think LeFleur will create much better spacing for the Titans offense and Mariota has his best year, if he stays healthy. They also brought in Dion Lewis from the Pats in the off-season. I don’t feel confident in taking a WR from them, but I do like Mariota and Henry. My concern is Lewis’s impact in LeFleurs offense. Does his addition, presumably in the passing game and formation changes with LeFleur’s offense devalue Henry? I know I can’t get Mariota late in the draft, but where should I target Henry? Should I avoid Henry?

ETA: Scoring - 1 pt PPR, 6 pt QB TD, standard ESPN scoring otherwise